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Erschienen in: Inflammation 5/2011

01.10.2011

Pentraxin 3 Increase is Much Less Pronounced Than C-Reactive Protein Increase After Surgical Procedures

verfasst von: Torbjörn Åkerfeldt, Anders Larsson

Erschienen in: Inflammation | Ausgabe 5/2011

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Abstract

Pentraxin 3 is an acute phase marker that belongs to the same protein family as C-reactive protein (CRP). The aim of this study was to compare the acute phase reactions of pentraxin 3 and CRP in humans. High sensitivity CRP and pentraxin 3 were analyzed in blood samples from orthopedic surgery (n = 29) and coronary bypass patients (n = 21). The samples were collected prior to surgery and 4 and 30 days after surgery, respectively. Both CRP and pentraxin 3 were significantly increased at day 4. Median pentraxin 3 values increased from 4,021 to 7,459 pg/mL in the orthopedic group and from 4,637 pg/mL to 10,419 pg/mL in the coronary bypass group while CRP increased from 6.3 mg/L to 151.6 mg/L and from 5.7 mg/L to 176.3 mg/L in the same groups. Pentraxin 3 shows a much smaller increment in humans in comparison with CRP.
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Metadaten
Titel
Pentraxin 3 Increase is Much Less Pronounced Than C-Reactive Protein Increase After Surgical Procedures
verfasst von
Torbjörn Åkerfeldt
Anders Larsson
Publikationsdatum
01.10.2011
Verlag
Springer US
Erschienen in
Inflammation / Ausgabe 5/2011
Print ISSN: 0360-3997
Elektronische ISSN: 1573-2576
DOI
https://doi.org/10.1007/s10753-010-9243-y

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