Anzeige
Erschienen in:
22.11.2016 | Original Scientific Report
Perioperative Risks of Dietary and Herbal Supplements
Erschienen in: World Journal of Surgery | Ausgabe 4/2017
Einloggen, um Zugang zu erhaltenAbstract
Background
Patients undergoing surgery often use Dietary and Herbal Supplements (DHS). We explored the risk of DHS–drug interactions in the perioperative setting.
Methods
In this cross-sectional prospective study, participants hospitalized for surgery completed a questionnaire regarding DHS use. We used pharmacological databases to assess DHS–drug interactions. We then applied univariate and multivariate logistic regression analyses to characterize patients at risk for DHS–drug interactions.
Results
Of 526 interviewees, 230 (44%) patients reported DHS use, with 16.5% reporting using DHS that could potentially interact with anesthesia. Twenty-four (10%) patients used DHS that could potentially interact with antithrombotic drugs taken perioperatively. The medical files of three patients included reports of intraoperative bleeding. The patient files of only 11% of DHS users documented DHS use.
Conclusions
DHS use poses a significant health risk due to potential interactions. Guidelines should emphasize perioperative management of DHS use.