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European Archives of Oto-Rhino-Laryngology

Erschienen in:

16.02.2016 | Review Article

Pharmacological agents used for treatment and prevention in noise-induced hearing loss

verfasst von: Muhammed Sedat Sakat, Korhan Kilic, Sami Bercin

Erschienen in: European Archives of Oto-Rhino-Laryngology | Ausgabe 12/2016

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Abstract

Noise is a stress factor that causes auditory, psychological and physiological effects. The realization that sudden loud noises or chronic exposure to noise in social and working environments can cause hearing loss has led to increased interest in noise-induced hearing loss (NIHL). The best means of preventing primary damage is protection against noise. Since this protection is not always possible for various reasons, the use of pharmacological agents to prevent or treat NIHL should also be considered. The purpose of this study is to discuss current pharmacological protection and treatment options in the light of the literature, since no such extensive reviews have been performed to date, including agents used for protection against and treatment of NIHL. We reviewed both animal and clinical studies, and these are discussed separately for ease of comprehension. For each agent, first animal studies, then clinical studies, if available, are discussed. We also performed a two-step search of the literature. In the first step, we searched the terms “noise induced hearing loss”, “treatment” and “protection” in Pubmed. Based on the results obtained, we identified the agents used for the treatment of and protection against NIHL. In the second step, we searched the names of the agents identified in the first step, together with the term “noise induced hearing loss,” and reviewed the results.

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Titel: Pharmacological agents used for treatment and prevention in noise-induced hearing loss
verfasst von: Muhammed Sedat Sakat
Korhan Kilic
Sami Bercin
Publikationsdatum: 16.02.2016
Verlag: Springer Berlin Heidelberg
Erschienen in: European Archives of Oto-Rhino-Laryngology / Ausgabe 12/2016
Print ISSN: 0937-4477
Elektronische ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-016-3936-2

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Springer Medizin

Pharmacological agents used for treatment and prevention in noise-induced hearing loss

Abstract

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Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

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Intrakapsuläre Tonsillektomie gewinnt an Boden

Bilateraler Hörsturz hat eine schlechte Prognose

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