Erschienen in:
Open Access
01.06.2014 | Letter
Platelet membrane potential: unable to pull the plug on sepsis
verfasst von:
Daniel A Schaer, James Penn, Sugeet Jagpal, Amay Parikh
Erschienen in:
Critical Care
|
Ausgabe 3/2014
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Excerpt
In a recent issue of
Critical Care, we read with interest the work of Gründler and colleagues [
1] regarding platelet mitochondrial depolarization reflecting disease severity in patients with sepsis. It has been established that, regardless of the source of sepsis, microcirculatory dysfunction with increased permeability and increased reactive oxygen species is similar among pathogens and leads to multi-organ dysfunction [
2]. …