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Erschienen in: International Journal of Legal Medicine 1/2019

17.02.2018 | Population Data

Population genetic data of Investigator HDplex markers in Han population from Southern China

verfasst von: Qiuling Liu, Hailun Nan, Xin He, Weiwei Wu, Dejian Lu

Erschienen in: International Journal of Legal Medicine | Ausgabe 1/2019

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Abstract

Allele frequencies and forensic statistical parameters for 12 STRs contained in the Investigator HDplex Kit (D2S1360, D3S1744, D4S2366, D5S2500, SE33, D6S474, D7S1517, D8S1132, D10S2325, D12S391, D18S51, and D21S2055) were estimated from a sample of 503 unrelated individuals from the Guangdong Han population of South China. No significant departure from the Hardy-Weinberg equilibrium or genetic linkage disequilibrium was observed (after Bonferroni correction). The expected heterozygosity ranged from 0.6411 to 0.9414. The allele frequencies in Guangdong Han significantly differed from that in Shanghai Han, Korea, Northern Italian, Swedish, Dutch, Somalia, and Argentinean populations at 2 to 12 loci. The markers included in the kit have highly polymorphic information that could be used for forensic DNA analysis as potential tools for differentiating Han population from other populations in the world.
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Literatur
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Zurück zum Zitat Zaykin D, Zhivotovsky L, Weir BS (1995) Exact tests for association between alleles at arbitrary numbers of loci. Genetica 96(1–2):169–178CrossRefPubMed Zaykin D, Zhivotovsky L, Weir BS (1995) Exact tests for association between alleles at arbitrary numbers of loci. Genetica 96(1–2):169–178CrossRefPubMed
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Zurück zum Zitat Buckleton JS, Triggs CM, Walsh SJ (2005) Forensic DNA evidence interpretation. CRC Press, Boca Raton Buckleton JS, Triggs CM, Walsh SJ (2005) Forensic DNA evidence interpretation. CRC Press, Boca Raton
Metadaten
Titel
Population genetic data of Investigator HDplex markers in Han population from Southern China
verfasst von
Qiuling Liu
Hailun Nan
Xin He
Weiwei Wu
Dejian Lu
Publikationsdatum
17.02.2018
Verlag
Springer Berlin Heidelberg
Erschienen in
International Journal of Legal Medicine / Ausgabe 1/2019
Print ISSN: 0937-9827
Elektronische ISSN: 1437-1596
DOI
https://doi.org/10.1007/s00414-018-1796-6

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