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Erschienen in: Journal of Hematopathology 3/2019

27.07.2019 | Case Report

Post-transplant lymphoproliferative disorder manifesting as lymphomatoid granulomatosis: report of two cases and review of the literature highlighting current challenges in pathologic classification

verfasst von: Jonathan J. Douds, Joyce E. Johnson, Ty W. Abel, John P. Greer, Mary Ann Thompson, Alexandra E. Kovach

Erschienen in: Journal of Hematopathology | Ausgabe 3/2019

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Abstract

Classification of viral- and immunodeficiency-associated lymphoproliferative disorders continues to evolve. Entities in these categories recognized in the 2016 revision of the World Health Organization Classification of Lymphoid Neoplasms show considerable morphologic overlap, and it is unclear whether the current classification conceptualizes the scenarios in which these lesions arise and how they might be best managed. Here, we report two cases of lymphoproliferative disorders meeting histologic criteria for lymphomatoid granulomatosis that arose following solid organ transplant. In reviewing the clinicopathologic features of these examples and those of similar cases in the literature, we highlight challenges in current classification and opportunities for their refinement.
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Metadaten
Titel
Post-transplant lymphoproliferative disorder manifesting as lymphomatoid granulomatosis: report of two cases and review of the literature highlighting current challenges in pathologic classification
verfasst von
Jonathan J. Douds
Joyce E. Johnson
Ty W. Abel
John P. Greer
Mary Ann Thompson
Alexandra E. Kovach
Publikationsdatum
27.07.2019
Verlag
Springer Berlin Heidelberg
Erschienen in
Journal of Hematopathology / Ausgabe 3/2019
Print ISSN: 1868-9256
Elektronische ISSN: 1865-5785
DOI
https://doi.org/10.1007/s12308-019-00364-w

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