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Erschienen in: European Radiology 7/2019

19.02.2019 | Chest

Potential of a machine-learning model for dose optimization in CT quality assurance

verfasst von: Axel Meineke, Christian Rubbert, Lino M. Sawicki, Christoph Thomas, Yan Klosterkemper, Elisabeth Appel, Julian Caspers, Oliver T. Bethge, Patric Kröpil, Gerald Antoch, Johannes Boos

Erschienen in: European Radiology | Ausgabe 7/2019

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Abstract

Objectives

To evaluate machine learning (ML) to detect chest CT examinations with dose optimization potential for quality assurance in a retrospective, cross-sectional study.

Methods

Three thousand one hundred ninety-nine CT chest examinations were used for training and testing of the feed-forward, single hidden layer neural network (January 2016–December 2017, 60% male, 62 ± 15 years, 80/20 split). The model was optimized and trained to predict the volumetric computed tomography dose index (CTDIvol) based on scan patient metrics (scanner, study description, protocol, patient age, sex, and water-equivalent diameter (DW)). The root mean-squared error (RMSE) was calculated as performance measurement. One hundred separate, consecutive chest CTs were used for validation (January 2018, 60% male, 63 ± 16 years), independently reviewed by two blinded radiologists with regard to dose optimization, and used to define an optimal cutoff for the model.

Results

RMSE was 1.71, 1.45, and 1.52 for the training, test, and validation dataset, respectively. The scanner and DW were the most important features. The radiologists found dose optimization potential in 7/100 of the validation cases. A percentage deviation of 18.3% between predicted and actual CTDIvol was found to be the optimal cutoff: 8/100 cases were flagged as suboptimal by the model (range 18.3–53.2%). All of the cases found by the radiologists were identified. One examination was flagged only by the model.

Conclusions

ML can comprehensively detect CT examinations with dose optimization potential. It may be a helpful tool to simplify CT quality assurance. CT scanner and DW were most important. Final human review remains necessary. A threshold of 18.3% between the predicted and actual CTDIvol seems adequate for CT quality assurance.

Key Points

• Machine learning can be integrated into CT quality assurance to improve retrospective analysis of CT dose data.
• Machine learning may help to comprehensively detect dose optimization potential in chest CT, but an individual review of the results by an experienced radiologist or radiation physicist is required to exclude false-positive findings.
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Metadaten
Titel
Potential of a machine-learning model for dose optimization in CT quality assurance
verfasst von
Axel Meineke
Christian Rubbert
Lino M. Sawicki
Christoph Thomas
Yan Klosterkemper
Elisabeth Appel
Julian Caspers
Oliver T. Bethge
Patric Kröpil
Gerald Antoch
Johannes Boos
Publikationsdatum
19.02.2019
Verlag
Springer Berlin Heidelberg
Erschienen in
European Radiology / Ausgabe 7/2019
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-019-6013-6

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