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European Archives of Oto-Rhino-Laryngology

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22.09.2017 | Head and Neck

Predictors of health-related quality of life in patients treated with neck dissection for head and neck cancer

verfasst von: Elise M. Gane, Steven M. McPhail, Anna L. Hatton, Benedict J. Panizza, Shaun P. O’Leary

Erschienen in: European Archives of Oto-Rhino-Laryngology | Ausgabe 12/2017

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Abstract

Patients with head and neck cancer can report reduced health-related quality of life several years after treatment. The aim of this study was to identify risk factors for reduced quality of life in patients up to 5 years following neck dissection. This cross-sectional study was conducted at two hospitals in Brisbane, Australia. Patients completed two measures of quality of life: the Neck Dissection Impairment Index (NDII), a region- and disease-specific tool, and the Assessment of Quality of Life-4 Domains, a general tool. Generalised linear modelling was used to determine which demographic and clinical variables were associated with quality of life. The cohort included n = 129 patients (71% male, median age 61, median 3 years since surgery). Positive nodal disease was associated with better quality of life on the NDII [e.g. N2 vs N0 coeff (95% CI) = 22.84 (7.33, 38.37)]. Worse quality of life was associated with adjuvant treatment [e.g. Independent Living domain model: surgery with chemoradiation vs surgery only coeff (95% CI) = −0.11 (−0.22, −0.01)]. Positive nodal disease was associated with better quality of life, which may be a reflection of response shift. Multimodality treatment leads to worse quality of life compared with surgery only.

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Titel: Predictors of health-related quality of life in patients treated with neck dissection for head and neck cancer
verfasst von: Elise M. Gane
Steven M. McPhail
Anna L. Hatton
Benedict J. Panizza
Shaun P. O’Leary
Publikationsdatum: 22.09.2017
Verlag: Springer Berlin Heidelberg
Erschienen in: European Archives of Oto-Rhino-Laryngology / Ausgabe 12/2017
Print ISSN: 0937-4477
Elektronische ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-017-4754-x

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Predictors of health-related quality of life in patients treated with neck dissection for head and neck cancer

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