I1 Proceedings of the 5th Annual United States Army Institute of Surgical Research Summer Undergraduate Research Internship Program 2017
Ryan Leon1, Katie Jensen2, Claire Abijay3, Troy Dolmetsch4, Natalie Koons5, Daniel N. Darlington6, Andrew Cap6, Xiaowu Wu6, Christopher P. Delavan6, Maryanne C. Herzig6, Barbara A. Christy6, Kelley M. Kempski7,8, August N. Blackburn9, Robert A. De Lorenzo 7,10, Megan B. Blackburn7, Matthew C. Donald11, Harold G. Klemcke7, Brenna K. Harrington12, Celestine J. He12,21, Belinda I. Gómez12, Tony Chao12, Joshua S. Little12, Tiffany C. Heard12, Michael A. Dubick12, David M. Burmeister12, Amy Xu6,13, Kerfoot Walker III 6,14, Arezoo Mohammadipoor6,14, Luis Rodriguez 6,14, Teryn Roberts 6,15, Andriy Batchinsky 6,15, Leopoldo Cancio 6, Ben Antebi 6, Ryan A. Walford16,17, Colby S. McIntosh16, Grantham C. Peltier16, Umang Sharma16, Robbie K. Montgomery16, Michael A. Meledeo16, James A. Bynum16, Sarah Lovelace18, Larry Estlack6, Lexi Kazen19, Lee C. Mangum6, Gerardo R. Garcia6, Kevin S. Akers6,20, Whitney Greene6, Lauren Cornell6
1Univeristy of Pennsylvania, Philadelphia, PA 19104, USA; 2Rice University, Houston, TX 77005, USA; 3Georgetown University, Washington, DC 20057, USA; 4East Tennessee State University, Johnson City, TN 37614, USA; 5Mercyhurst University, Erie, PA 16504, USA; 6US Army Institute of Surgical Research, JBSA Fort Sam Houston, TX 78234, USA; 7Tactical Combat Casualty Care Research Task Area, US Army Institute of Surgical Research, JBSA Fort Sam Houston, TX 78234, USA; 8Department of Biomedical Engineering, University of Delaware, Newark, DE 19716, USA; 9South Texas Diabetes and Obesity Institute, University of Rio Grande Valley, Brownsville, TX 78520, USA; 10University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA; 11Mississippi State University, Mississippi State, MS 39762, USA; 12Damage Control Resuscitation Task Area, US Army Institute of Surgical Research, JBSA Fort Sam Houston, TX 78234, USA; 13Stanford University, Stanford, CA, USA; 14Oak Ridge Institute for Science and Education, Oak Ridge, TN, USA; 15The Geneva Foundation, Tacoma, WA, USA; 16Blood and Coagulation Task Area, US Army Institute of Surgical Research, JBSA Fort Sam Houston, TX 78234, USA; 17Dwight Look College of Engineering, Department of Biomedical Engineering, Texas A&M University, College Station, TX 77840, USA; 18Trinity University, San Antonio, TX 78212, USA; 19University of Wisconsin, Madison, WI, USA; 20Brooke Army Medical Center, JBSA Fort Sam Houston, TX, USA; 21Department of Biological Sciences, Northwestern University, Evanston, IL 60201, USA
Correspondence: Lauren Cornell (lauren.e.cornell.ctr@mail.mil)
P1 Simultaneous measurement of thrombin and plasmin activity: the thrombin / plasmin ratio
Ryan Leone1, Claire Abijay2, Troy Dolmetsch3, Natalie Koons4, Daniel N. Darlington5, Andrew Cap5, Xiaowu Wu5
1Univeristy of Pennsylvania, Philadelphia, PA 19104, USA; 2Georgetown University, Washington, DC 20057, USA; 3East Tennessee State University, Johnson City, TN 37614, USA; 4Mercyhurst University, Erie, PA 16504, USA; 5US Army Institute of Surgical Research, JBSA Fort Sam Houston, TX 78234, USA
Correspondence: Xiaowu Wu (Xiaowu.wu.civ@mail.mil)
P2 PGI2 modulates cAMP levels during aggregation in platelets
Natalie Koons1, Ryan Leone2, Claire Abijay3, Troy Dolmetsch4, Xiaowu Wu5, Andrew P. Cap5, Daniel N. Darlington5
1Mercyhurst University, Erie, PA 16504, USA; 2Univeristy of Pennsylvania, Philadelphia, PA 19104, USA; 3Georgetown University, Washington, DC 20057, USA; 4East Tennessee State University, Johnson City, TN 37614, USA; 5US Army Institute of Surgical Research, JBSA Fort Sam Houston, TX 78234, USA
Correspondence: Daniel N. Darlington (Daniel.n.darlington.civ@mail.mil)
P3 Determination of a safe dose of mesenchymal stem cells for systemic administration
Claire Abijay1, Ryan Leone2, Natalie Koons3, Troy Dolmetsch4, Daniel N. Darlington5, Andrew P. Cap5, Xiaowu Wu5
1Georgetown University, Washington, DC 20057, USA; 2Univeristy of Pennsylvania, Philadelphia, PA 19104, USA; 3Mercyhurst University, Erie, PA 16504, USA; 4East Tennessee State University, Johnson City, TN 37614, USA; 5US Army Institute of Surgical Research, JBSA Fort Sam Houston, TX 78234, USA
Correspondence: Xiaowu Wu (Xiaowu.wu.civ@mail.mil)
P4 Severe trauma leads to a fall in triphosphates and rise in cAMP in platelets
Troy Dolmetsch1, Natalie Koons2, Ryan Leone3, Claire Abijay4, Andrew P. Cap5, Xiaowu Wu5, Daniel N. Darlington5
1East Tennessee State University, Johnson City, TN 37614, USA; 2Mercyhurst University, Erie, PA 16504, USA; 3Univeristy of Pennsylvania, Philadelphia, PA 19104, USA; 4Georgetown University, Washington, DC 20057, USA; 5US Army Institute of Surgical Research, JBSA Fort Sam Houston, TX 78234, USA
Correspondence: Xiaowu Wu (Xiaowu.wu.civ@mail.mil) and Daniel N. Darlington (Daniel.n.darlington.civ@mail.mil)
P5 Evaluation of an antimitogenic treatment on the immunomodulatory activity of human mesenchymal stem cells
Katie J. Jensen1, Christopher P. Delavan2, Maryanne C. Herzig2, Barbara A. Christy2, Andrew P. Cap2
1Rice University, Houston, Houston, TX 77005, USA; 2US Army Institute of Surgical Research, JBSA Fort Sam Houston, TX 78234, USA
Correspondence: Maryanne C. Herzig (maryanne.c.herzig.ctr@mail.mil) and Andrew P. Cap
P6 Static dimensional comparison of low-fidelity airway trainers to Human Morphometrics
Kelley M. Kempski1,2, August N. Blackburn3, Robert A. De Lorenzo1,4, Megan B. Blackburn1
1Tactical Combat Casualty Care Research Task Area, US Army Institute of Surgical Research, JBSA Fort Sam Houston, TX 78234, USA; 2Department of Biomedical Engineering, University of Delaware, Newark, DE 19716, USA; 3South Texas Diabetes and Obesity Institute, University of Rio Grande Valley, Brownsville, TX 78520, USA; 4University of Texas Health Science Center at San Antonio, TX 78229, USA
Correspondence: Megan B. Blackburn (megan.b.blackbrun2.civ@mail.mil)
Human | SynDaver* | SynDaver CT | Laerdal* | Laerdal CT | SimAir* | SimAir CT | |
---|---|---|---|---|---|---|---|
Height mouth opens (cm) | 4.78±0.83 | 5.98 (0.93) | – | 4.52 (0.38) | – | 8.10 (0.99) | – |
Neck circumference (cm) | 36.6±3.5 | 33.4 (0.18) | 36.02 (0.43) | 43.55 (0.98) | 42.84 (0.96) | 41.23 (0.91) | 40.15 (0.85) |
Tracheal length (cm) | 8.6±1.1 | 9.54 (0.8) | 9.04 (0.66) | 3.27 (0.0) | 3.30 (0.0) | 7.83 (0.24) | 8.01 (0.30) |
Epiglottis tip—posterior pharyngeal wall (cm) | 0.9±0.4 | 1.67 (0.97) | 1.54 (0.95) | 3.54 (0.99) | 2.35 (0.99) | 1.48 (0.93) | 1.10 (0.69) |
Angle right main stem bronchus (°) | 25 | 49.57 | 53.80 | 29.15 | 32.37 | 19.67 | – |
Total airway volume (cm3) | 22.5±9.0 | – | 106.72 (0.99) | – | 170.18 (0.99) | – | 104.84 (0.99) |
Oral pharynx volume (cm3) | 3.6±2.6 | – | 20.06 (0.99) | – | 27.37 (0.99) | – | 7.99 (0.95) |