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Pediatric Radiology
Erschienen in: Pediatric Radiology 11/2008

01.11.2008 | Review

Receptor imaging of pediatric tumors: clinical practice and new developments

verfasst von: Heike E. Daldrup-Link, Randall A. Hawkins, Reinhard Meier, Robert E. Goldsby, Dmitri Artemov

Erschienen in: Pediatric Radiology | Ausgabe 11/2008

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Abstract

Pediatric cancers often have specific molecular fingerprints making them primary candidates for the development of targeted imaging techniques. Tumor-targeted tracers have the potential to substantially advance the sensitivity and specificity of imaging techniques by improving tumor detection and characterization. This article reviews various approaches to target tumors via specific tumor antigens, tumor cell surface receptors and specific surface receptors of the endothelial cells of the tumor vessels. These new applied molecular imaging techniques are expected to improve our knowledge of the biology of pediatric cancers and, ultimately, to help in the development of tailored diagnoses and therapies, which may ultimately lead to better individual long-term outcomes.
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Metadaten
Titel
Receptor imaging of pediatric tumors: clinical practice and new developments
verfasst von
Heike E. Daldrup-Link
Randall A. Hawkins
Reinhard Meier
Robert E. Goldsby
Dmitri Artemov
Publikationsdatum
01.11.2008
Verlag
Springer-Verlag
Erschienen in
Pediatric Radiology / Ausgabe 11/2008
Print ISSN: 0301-0449
Elektronische ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-008-0878-x

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