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01.07.2007 | Letter to the Editor

Response from authors of “Extracellular matrix alterations in conventional renal cell carcinomas by tissue microarray profiling influenced by the persistent, long-term, low-dose ionizing radiation exposure in humans”

verfasst von: Alina Romanenko, Luisa Morell-Quadreny, David Ramos, Valentin Nepomnyaschiy, Alexander Vozianov, Antonio Llombart-Bosch

Erschienen in: Virchows Archiv | Ausgabe 1/2007

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Excerpt

The Chernobyl accident introduced for the first time the problem of chronic, persistent, long-term, low-dose exposure to ionizing radiation (IR) in humans. Currently, 21 years after the accident at the Chernobyl Power Plant in Ukraine (70 Km from Kiev), approximately 17 million people live in the radiocontaminated area and have been exposed to low-dose IR. Information regarding irradiation of the Ukrainian population is based on the official reports provided by the Ukrainian Government and the Ukrainian Academy of Medical Sciences. Morbidity of malignant renal tumors in adults during the period 1986–2006 increased from 4.7 to 9.9 per 100,000 of total population (from 6.0 to 12.6 per 100,000 of the male population and from 3.6 to 7.5 per 100,000 of the female population in Ukraine) [4]. …

Little JB (2000) Radiation carcinogenesis. Carcinogenesis 21:397–404PubMedCrossRef

Romanenko A, Morell-Quadreny L, Nepomnyaschy V, Vozianov A, Llombart-Bosch A (2000) Pathology and proliferative activity of renal-cell carcinomas and renal oncocytomas in patients with different radiation exposure after the Chernobyl accident in Ukraine. Int J Cancer 87:880–883PubMedCrossRef

Romanenko A, Morell-Quadreny L, Nepomnyaschy V, Vozianov A, Llombart-Bosch A (2000) Radiation sclerosing proliferative atypical nephropathy of peritumoral tissue of renal-cell carcinomas after the Chernobyl accident in Ukraine. Virchows Arch 438:146–158CrossRef

Saydackova N, Startzeva L (2006) State of urologic assistance for the population of Ukraine and the ways to improve it. Annual Reports of the Health Care in Ukraine, Ukrainian Ministry of Health, Kiev, pp 214–243

Wu LJ, Randers-Pehrson G, Xu A, Waldren CA, Geard CR, Yu ZL, Hei TK (1999) Targeted cytoplasmic irradiation with alpha particles induces mutations in mammalian cells. Proc Natl Acad Sci USA 96:4959–4964PubMedCrossRef

Titel: Response from authors of “Extracellular matrix alterations in conventional renal cell carcinomas by tissue microarray profiling influenced by the persistent, long-term, low-dose ionizing radiation exposure in humans”
verfasst von: Alina Romanenko
Luisa Morell-Quadreny
David Ramos
Valentin Nepomnyaschiy
Alexander Vozianov
Antonio Llombart-Bosch
Publikationsdatum: 01.07.2007
Verlag: Springer-Verlag
Erschienen in: Virchows Archiv / Ausgabe 1/2007
Print ISSN: 0945-6317
Elektronische ISSN: 1432-2307
DOI: https://doi.org/10.1007/s00428-007-0442-3

Springer Medizin

Response from authors of “Extracellular matrix alterations in conventional renal cell carcinomas by tissue microarray profiling influenced by the persistent, long-term, low-dose ionizing radiation exposure in humans”

Excerpt

Neu im Fachgebiet Pathologie

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie

Springer Medizin

Excerpt

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Vergleichende Pathologie in der onkologischen Forschung

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