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19.02.2020 | Original Contribution

Risk factors for obsessive–compulsive symptoms. Follow-up of a community-based youth cohort

verfasst von: Pedro Macul Ferreira de Barros, Maria Conceição do Rosário, Natalia Szejko, Natália Polga, Guaraci de Lima Requena, Beatriz Ravagnani, Daniel Fatori, Marcelo Camargo Batistuzzo, Marcelo Queiroz Hoexter, Luis Augusto Rohde, Guilherme Vanoni Polanczyk, James Frederick Leckman, Eurípedes Constantino Miguel, Pedro Gomes de Alvarenga

Erschienen in: European Child & Adolescent Psychiatry | Ausgabe 1/2021

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Abstract

Environmental factors are at least as important as genetic factors for the development of obsessive–compulsive symptoms (OCS), but the identification of such factors remain a research priority. Our study aimed to investigate the association between a broad scope of potential risk factors and OCS in a large community cohort of children and adolescents. We evaluated 1877 participants and their caregivers at baseline and after 3 years to assess various demographic, prenatal, perinatal, childhood adversity, and psychopathological factors. Mean age at baseline was 10.2 years (SD 1.9) and mean age at follow-up was 13.4 years (SD 1.9). Reports of OCS at baseline and follow-up were analyzed using latent variable models. At preliminary regression analysis, 15 parameters were significantly associated with higher OCS scores at follow-up. At subsequent regression analysis, we found that eight of these parameters remained significantly associated with higher follow-up OCS scores while being controlled by each other and by baseline OCS scores. The significant predictors of follow-up OCS were: lower socioeconomic status (p = 0.033); lower intelligence quotient (p = 0.013); lower age (p < 0.001); higher maternal stress level during pregnancy (p = 0.028); absence of breastfeeding (p = 0.017); parental baseline OCS (p = 0.038); youth baseline anxiety disorder (p = 0.023); and youth baseline OCS scores (p < 0.001). These findings may better inform clinicians and policymakers engaged in the mental health assessment and prevention in children and adolescents.

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Titel: Risk factors for obsessive–compulsive symptoms. Follow-up of a community-based youth cohort
verfasst von: Pedro Macul Ferreira de Barros
Maria Conceição do Rosário
Natalia Szejko
Natália Polga
Guaraci de Lima Requena
Beatriz Ravagnani
Daniel Fatori
Marcelo Camargo Batistuzzo
Marcelo Queiroz Hoexter
Luis Augusto Rohde
Guilherme Vanoni Polanczyk
James Frederick Leckman
Eurípedes Constantino Miguel
Pedro Gomes de Alvarenga
Publikationsdatum: 19.02.2020
Verlag: Springer Berlin Heidelberg
Erschienen in: European Child & Adolescent Psychiatry / Ausgabe 1/2021
Print ISSN: 1018-8827
Elektronische ISSN: 1435-165X
DOI: https://doi.org/10.1007/s00787-020-01495-7

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