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Breast Cancer Research

Erschienen in:

01.10.2010 | Review

Role of miR-10b in breast cancer metastasis

verfasst von: Li Ma

Erschienen in: Breast Cancer Research | Ausgabe 5/2010

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Abstract

Ninety percent of cancer-related mortality is caused by metastasis. Current cancer treatments can control many primary tumors but rarely stop the metastatic spread. Accumulating evidence demonstrates that miRNAs are involved in cancer initiation and progression. Furthermore, several miRNAs have been found to regulate metastasis. In particular, recent studies provide the first functional evidence that overexpression of a specific miRNA, miR-10b, can contribute to the development of metastasis, which can be exploited therapeutically in treating breast cancer metastasis in mice. Further in-depth analysis should provide more precise evaluation of the roles, mechanisms, and therapeutic utility of this miRNA in breast cancer.

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Titel: Role of miR-10b in breast cancer metastasis
verfasst von: Li Ma
Publikationsdatum: 01.10.2010
Verlag: BioMed Central
Erschienen in: Breast Cancer Research / Ausgabe 5/2010
Elektronische ISSN: 1465-542X
DOI: https://doi.org/10.1186/bcr2720

Springer Medizin

Role of miR-10b in breast cancer metastasis

Abstract

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Springer Medizin

Abstract

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