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Metabolic Brain Disease

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01.06.2015 | Review Article

Role of neurotrophin in the taste system following gustatory nerve injury

verfasst von: Lingbin Meng, Xin Jiang, Rui Ji

Erschienen in: Metabolic Brain Disease | Ausgabe 3/2015

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Abstract

Taste system is a perfect system to study degeneration and regeneration after nerve injury because the taste system is highly plastic and the regeneraton is robust. Besides, degeneration and regeneration can be easily measured since taste buds arise in discrete locations, and nerves that innervate them can be accurately quantified. Neurotrophins are a family of proteins that regulate neural surival, function, and plasticity after nerve injury. Recent studies have shown that neurotrophins play an important role in the developmental and mature taste system, indicating neurtrophin might also regulate taste system following gustatory nerve injury. This review will summarize how taste system degenerates and regenerates after gustatory nerve cut and conclude potential roles of neurotrophin in regulating the process.

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Titel: Role of neurotrophin in the taste system following gustatory nerve injury
verfasst von: Lingbin Meng
Xin Jiang
Rui Ji
Publikationsdatum: 01.06.2015
Verlag: Springer US
Erschienen in: Metabolic Brain Disease / Ausgabe 3/2015
Print ISSN: 0885-7490
Elektronische ISSN: 1573-7365
DOI: https://doi.org/10.1007/s11011-014-9626-0

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