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Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology 3/2020

Open Access 11.12.2019 | Review Article

Scleral buckling—a brief historical overview and current indications

verfasst von: Aijing Wang, Martin P. Snead

Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology | Ausgabe 3/2020

Abstract

The key to successful management of rhegmatogenous retinal detachment (RRD) is to find and seal all of the retinal breaks, and the two main surgical techniques used to achieve this are scleral bucking (SB) or pars plana vitrectomy (PPV). Techniques for SB have remained mostly unchanged for the last 60 years, whilst PPV techniques and instruments have developed substantially over that time and have greatly contributed to increased success rate for types and configurations of retinal detachments unsuitable or difficult to manage with buckling alone. However, there is a growing dependency to rely on PPV as the sole and only approach for repair of all types of retinal detachment, such that some centres are no longer offering training in scleral buckling. There are also many studies comparing SB with PPV, but many of these lack information on the type, technique or rationale for deployment of the buckle. Many studies deploy the same scleral buckle technique without customising it to the type, position or number of tears being treated. Scleral buckling is not a one-size-fits-all technique. It requires careful patient selection and careful buckle selection and orientation tailored to the tear(s) to ensure success. When used appropriately, it is a simple and highly effective technique, particularly for retinal dialyses, round retinal hole detachments and selected cases of retinal detachment associated with horseshoe retinal tears. There is no doubt that for some more complex cases, such as multiple large breaks, giant retinal tears, bullous detachments and cases complicated by proliferative retinopathy, PPV offers a safer and more effective management. However, SB remains an important and relevant surgical technique, and for the right cases, the results can be superior to PPV with reduced comorbidity.
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Introduction

Scleral buckling (SB) has been used either as the primary or as an adjunctive treatment for rhegmatogenous retinal detachment (RRD) repair for over 60 years. However, certain types or configurations of retinal detachment are difficult or impossible to manage with scleral buckling alone, and the advent and development of pars plana vitrectomy (PPV) for retinal detachment repair has greatly enhanced the outcomes in such cases. Internal approaches are now so widespread for all types of retinal detachment repair that some surgeons are no longer being exposed to training in scleral buckling. This paper reviews the literature and highlights the important role that buckling continues to offer for successful retinal detachment repair and describes some of the key surgical elements.

A brief history of scleral buckling

Any attempt to summarise the history of retinal detachment repair must begin with Jules Gonin’s pioneering observation that accurate localisation and sealing of the retinal break(s) was the key to successful re-attachment. A common belief in his era was that retinal breaks were either not present or were otherwise secondary to retinal detachment [13]. Since then, many different techniques have been developed to treat retinal breaks, but this article focuses particularly on the roles of scleral buckling.
Scleral buckling surgical techniques originally evolved from scleral resection [4] which was initially developed to reduce the size of the eyeball [5] or as an attempt to strengthen the sclera and prevent stretching. It was subsequently realised that as a result, this actually brought the retinal pigment epithelium and neurosensory retina together, assisting retinal re-attachment [6]. Full thickness scleral resection was then refined to lamellar scleral resection in 1949 by Shapland [7] to decrease the ocular complications from scleromalacia—a common association with rhegmatogenous retinal detachment. The area of the resection often resulted in a buckling effect, and attempts were made to localise the resection site over the break, in order to aid retinal re-attachment.
However, even lamellar resection carried a high risk of comorbidity and attempts to achieve the same buckling effect without risking tissue resection were therefore developed. These techniques included Weve’s ‘reefing’ procedures [8], scleral out-folding procedures [911], scleral in-folding procedures [1217] and scleral shortening by shrinkage with diathermy [18]. With all of these techniques, the main objective was the ‘buckling’ effect that was produced, which became a key factor in successful retinal re-attachment.
Whilst the scleral shortening techniques were being elaborated, in 1949, Ernst Custodis developed an explant specifically to produce a buckling effect for retinal detachment repair whilst circumventing the risks associated with scleral shortening and resection (Fig. 1) [19]. Custodis introduced a polyviol explant to buckle the sclera, breaks were treated with diathermy and a non-drainage procedure was used. He reported his technique with a consecutives series of 515 patients with an 83.3% rate of success—a figure that compares favourably with many series being published 50 years later [19].
In the USA, scleral buckling was also being developed by Charles Schepens, who deployed a polyethylene encircling tube and drained subretinal fluid along with diathermy [2024]. Schepens also contributed hugely by developing and popularising the use of the binocular indirect ophthalmoscope which greatly enhanced the wide-field fundus visualisation vital for break identification and retinal detachment repair [25, 26]. In New York, Harvey Lincoff, perhaps above all others, made many important and varied contributions to the development of scleral buckling. He introduced silicone sponges as explants; developed new needles for scleral sutures; published extensively on the advantages of cryotherapy over diathermy, the importance of finding the retinal break (now universally known as ‘Lincoff’s rules’ [27]) and the importance of buckle orientation for different configurations and types of retinal break; and highlighted the lower comorbidity of non-drainage of subretinal fluid [2835]. The techniques he developed 50 years ago have withstood the test of time and remain as relevant in retinal detachment repair today.

Changes in retinal detachment surgery

Scleral buckling became an established technique for retinal detachment repair, with long-term studies reporting a 95% final success rate at 20-year follow-up [36], only 13–23% re-operation rate [3638] and a median visual acuity at 6/12 at long-term follow-up [36, 38]. Other large studies have shown with careful case selection a 99% single operation success, a figure never achieved in any vitrectomy series [39]. However, since the development of pars plana vitrectomy by Machemer [40, 41], there has been a great shift towards PPV over SB in the surgical management of RRD [4251], and whilst both have a role to play, there have been major debates [52] about which type of surgery is better suited for which type of patients. Unfortunately, there is a paucity of robust evidence to definitively confirm either being superior to the other, or which is indicated in which patients, largely because of failure to sub-classify different retinal break types in the comparison analysis (Table 1) [53].
Table 1
Cambridge guide to characteristic retinal break types in rhegmatogenous retinal detachment [RRD]
Break type
Sex
PHM
Refractive error
Fellow eye pathology
Horseshoe tear
M=F
OFF
Myopic
15%
Round hole
F>M
ON
Myopic
50%
Dialysis
M>F
ON
Hypermetropic
15%
Giant retinal tear
M=F
OFF
Myopic
Up to 80%
Macular hole
M=F
OFF
Highly myopic
Rare
Retinoschisis RRD
M
ON
Hyperopic
80%
PHM = posterior hyaloid membrane
One of the largest trials comparing SB and PPV was conducted by the SPR (scleral buckling versus primary vitrectomy in rhegmatogenous retinal detachment) study group. It concluded that SB was superior for phakic patients, as improvement in best corrected visual acuity (BCVA) was significantly better (p = 0.0005) in the SB group compared to the PPV group, but PPV was better for aphakic/pseudophakic patients in terms of anatomical success [54]. There was no significant difference in improvement of BCVA between the SB and PPV groups in aphakic/pseudophakic patients (p = 0.1033), which was the primary outcome of the study. The study argued that PPV was better for aphakic/pseudophakic patients due to better primary anatomical success rates (SB 53.4%, PPV 72%, p = 0.0020) and fewer retina-affecting operations in the PPV group. However, the final anatomical success rates were not significantly different. Therefore, the evidence to support PPV for aphakic/pseudophakic patients was not as convincing as the evidence to support SB for phakic patients. It is also important to note that the primary anatomical success rates in the SPR trial were much lower than those in other trials [55, 56]. The study did not directly analyse PPV alone in comparison with PPV combined with SB, but found that anatomical results were superior in aphakic/pseudophakic patients that incorporated an additional buckle. With combined PPV and buckle, there was an 11.4% failure rate, whereas with PPV alone, 40.9% of patients re-detached. This was a very significant difference and other studies have also shown higher rates of success in PPV combined with SB over PPV alone, lending support to the role of scleral buckling as an adjunct to vitrectomy in certain circumstances, in addition to those that can be managed successfully by buckling alone [57]. Unfortunately, no details were reported in the comparison study on SB techniques, merely that radial sponges or encircling elements were used.
Many other studies, similar to the SPR study group, support the use of PPV for pseudophakic eyes [54, 55, 58], whereas other studies have shown no difference between SB versus PPV in pseudophakic eyes [5961]. There is little evidence or logic to suggest one size or technique fits all scenarios. The surgical objective must be to identify and close all retinal breaks with a single (first) procedure. Patients may therefore require either PPV or SB or a combination of the two to achieve this objective and surgeons should not be restricted in their approach to one or the other.
The general consensus is that an ‘uncomplicated RRD’ can be managed with scleral buckling alone and tends to give higher rates of success [54, 59, 6266]. However, the development and increasing use of PPV for a wide variety of vitreoretinal disorders has perhaps led to an incremental decline in the training and therefore deployment of SB, even for cases of ‘simple’ RRD [67].
The use of SB combined with PPV for treating inferior tears [68] versus PPV alone also remains open to debate. Some groups argue that PPV with tamponade alone is sufficient as a primary approach [6971], whilst others make the case that scleral buckles can provide an important adjunct to the internal tamponade to achieve successful closure of all breaks [72, 73]. Many studies have shown that eyes with inferior breaks generally have worse prognosis than eyes with superior breaks [46, 68, 74]. Studies reporting PPV alone for RRD with inferior tears give primary success of around 81% with no significant improvement when an additional buckle was used [69, 70]. In contrast, other studies in which a combined approach was deployed reported a single operation success rate of 95% [72].
A weakness common to many of the studies comparing SB and PPV for RRD is a paucity of data on the type, technique or rationale for deployment of the buckle, in contrast to the more uniform approach of three-port PPV. Many studies deploy the same scleral buckle technique without customising it to the type, position or number of tears being treated [44, 55, 56]. The importance of pinpoint accuracy in buckle localisation highlighted by Lincoff, Scott and others [27, 65, 7577] remains the key factor in successful buckle deployment. It is perhaps not surprising that in comparative studies of SB versus PPV, failures in the former were all caused by malposition of the buckle [44, 55]. When buckles are not appropriately selected or localised to achieve break closure according to the exact size and position of the retinal tear, breaks will not close and re-attachment will not be achieved. Most studies that analyse SB versus PPV report the use of circumferential buckles or 360° encircling buckle. However, ‘fish-mouthing’ is a risk if horseshoe tears are managed in this way [78], unless combined with an internal tamponade. Circumferential buckles are better suited and highly effective for the repair of dialyses and round retinal holes in which the vitreous and posterior hyaloid membrane are characteristically attached, and radial sponges are better suited for horseshoe tears [75].
In another study, the technique of SB was the universal use of a silicone tyre and band irrespective of size, position, number and position of tears [56]. As patient selection is a key component to the success of scleral buckling surgery, results from these studies need to be interpreted with caution. When scleral buckling is carefully selected according to operative findings, complete single operation success can be achieved in as high as 93.6% [60] and 99% [39].
The United Kingdom National Ophthalmology Database Study showed that the re-operation rate was lower for patients who underwent SB (12.3%) versus PPV (13.0%) or PPV+SB (14.5%), although the figures did not reach statistical significance. Also, the rates of visual success were higher for SB (71.6%), although this was not significantly higher than PPV (69.7%) or PPB+SB (65.6%) [79]. This set of results is echoed in the Medicare data from the USA, where the rates for second operation were higher for PPV (21.2%) when compared with SB (19.2%) [80]. The Medicare data also reported that patients undergoing PPV were two times more likely to experience adverse outcomes compared to the scleral buckling group (OR 2.019; 95% CI 1.412, 2.889). Another smaller study also shows patients treated with SB required lower number of re-operations compared to PPV [81]. Interestingly, a retrospective study of 1530 eyes conducted in Singapore showed that scleral buckling had the highest primary anatomical success (88.8 vs 78.6%) and the best functional outcome compared to PPV (86.1 vs 72.5%), and the SB group also had less complications [82]. This study unfortunately did not specify the type of tears that were being treated, but it is likely that round hole retinal detachments which respond well to buckling were a significant proportion of that population [83]. If so, this would echo the UK study of the largest reported series of RRD secondary to atrophic round retinal holes in which 99% single op success was achieved [39] emphasising the importance of careful case selection and break type being tailored to the surgical approach.
In summary, rhegmatogenous retinal detachment is a highly heterogeneous disease and its management equally so. Scleral buckling retains a very important role in the management of certain types of RRD, either as a primary approach with very high single operation success rate and low comorbidity, or as an adjunct to enhance a combined internal approach with PPV. The definition of anatomical and visual success varies between studies, but the primary goal for surgeons must be an approach tailored to the individual patient’s needs that will result in permanent re-attachment with a single procedure whilst minimising comorbidity.

How does scleral buckling work?

Primary scleral buckling

Whether an internal, external or combined approach is chosen, the principal objective is to close all retinal breaks and maintain closure by preventing any further recruitment of subretinal fluid for long enough for a retinopexy adhesion to mature to full strength.
In primary RRD, once this has been achieved, the tamponade (either internal or external) serves no further purpose in maintaining retinal re-attachment as evidenced by the temporary nature of gas tamponades. There is, however, usually no need to remove a scleral buckle once primary repair has been achieved, but in the same way that a gas tamponade is temporary, it is quite safe to do so should the need arise.

Secondary scleral buckling

Scleral buckling can also play an important adjunctive role to PPV in the management of more complex RRD associated with multiple or large retinal breaks, proliferative vitreoretinopathy (PVR), schisis and patients in whom postoperative posturing with PPV alone may be problematic [84].

Surgical technique

The specific surgical techniques for scleral buckling are many and varied, but there are three main fundamental principles which are key to primary success:
1.
A thorough preoperative and intraoperative examination is essential to identify and localise all retinal breaks [85] and the pioneering ‘rules’ introduced by Harvey Lincoff and Dick Gieser [27] remain as an important foundation on which to base the examination.
 
2.
Accurate retinopexy.
 
3.
Correct buckle selection and pinpoint accurate localisation to occlude the break and maintain apposition of RPE and neurosensory retina whilst the retinopexy matures to full strength.
 
Most failures of scleral buckling arise from either missed primary breaks or inaccurate localisation of the buckle and thereby failure of break closure.

Examination of the sclera and retina

A full peritomy should be performed to ensure all parts of the sclera and retina (both attached and detached) can be fully examined with scleral depression (Fig. 2a, b). Opening the conjunctiva 2–3 mm posterior to the limbus provides good scleral access without any disturbance to the Tenon’s capsule/conjunctival complex which reduces scarring as well as avoiding disruption to the limbal stem cell array.
The four rectus muscles are isolated on bridle sutures with great care taken at this step to avoid splitting a muscle, slinging an oblique or stripping the muscle capsule all of which increase the risks of restrictive diplopia postsurgery. The peripheral retina can then be meticulously examined to identify all breaks and the sclera for any associated scleromalacia which might compromise or preclude safe buckle suture placement (Fig. 3).
Following examination, each retinal break must be localised and marked (see Figs. 2b, 4 and 5). For small tears, one indentation may be sufficient to help decide the size of buckling material. For larger tears, three indentation marks may be needed to mark the anterior horns and the posterior limit.

Sealing the break

After localising the breaks, retinopexy is applied accurately to each break, ensuring no gaps are left with large tears and no area retreated which might compromise the RPE/Muller cell adhesion. If the detachment is bullous or too elevated to deploy retinopexy accurately to both RPE and neurosensory retina, then the subretinal fluid may be released with an air injection to restore the volume and IOP in the D-ACE surgical sequence [86]. Accurate localisation and retinopexy is a most important element of the operation. If any tears are missed, the primary surgery will fail. Cryotherapy is most commonly used and often better at highlighting small tears in the periphery compared to laser and has better outcomes than laser [87] in the context of scleral buckling for retinal detachment (Fig. 6).

Choice of buckle

There are three main different categories of buckle deployment: radial buckle, segmental circumferential or encircling. The types, number and magnitude of the retinal tears will influence the selection.
In general, a single horseshoe tear is most effectively closed with a radial sponge (Fig. 7). The figures provided show an illustrative guide for applying a radial sponge, from EUA to retinopexy, localisation and then buckle placement (Figs. 3, 4, 5, 6, 7, 8, 9, 10, 11 and 12). Retinal dialyses and atrophic retinal hole are managed very effectively with a circumferential explant. Multiple and/or very large tears are usually more safely and effectively managed with an internal approach.
After the correct type of buckle is selected, accurate suture placement (Fig. 8) is the next key step as this will determine not only the localisation of the buckle over the break but also importantly the buckle height. Suturing the buckle to the sclera is a skill that requires training and practice. The sutures should be deep enough to be secure but not so deep to lead to premature loss of subretinal fluid which could compromise intraocular pressure or result in choroidal haemorrhage. The scleral passage should be uniform in depth and as long as feasible (Figs. 9, 10 and 11b). A spatulate needle with two cutting edges attached to a 5-0 non-absorbable suture is generally the material of choice.
The mattress suture width will be determined by the size of the buckling material, which is in turn determined by the size of the tear. The diameter of the buckle must be big enough to cover both apices of the horseshoe tear, and the width of the suture (the extra-scleral portion) must be wider than the diameter of the explant in order to achieve an adequate buckling effect to drape and close the break effectively. No amount of suture tightening will achieve an adequate buckle height if the sutures are too close to the explant—the sutures will simply cut out of their scleral passage. Too far apart and the explant may shift position allowing one or another horn of a horseshoe tear to leak.
The length of the buckle must close both the posterior edge of the break and the limit of separation of the posterior hyaloid membrane at the anterior horns of a horseshoe tear. Circumferential buckles are placed in a similar way, with sutures on either side of rectus muscles when required for extensive circumferential breaks.
When tying the surgical knot, the first throws determine the tension and hence the buckle height—generally a triple throw being sufficient for a for 3, 4 or 5 mm diameter sponge (Fig. 11b). A quadruple throw may be required for 7.5 mm sponges, although these are rarely used now with internal approaches being preferred for such very large single horseshoe tears. The knot must be balanced, so that equal tension is produced on both sides of the knot when complete (Fig. 12). Whilst the knots are tied, it is important to monitor the intraocular pressure. The risk of increased intraocular pressure is increased with the size of the buckling material being used.

Scleral buckling for different types of detachments

Retinal detachment secondary to horseshoe tears

Much of the literature refers to uncomplicated retinal tears being most suitable for scleral buckling. The simplest case of a retinal detachment could possibly be defined as a single horseshoe tear with detachment extending up to two quadrants. By following the main principles of scleral buckling, the tear is first localised and treated with retinopexy and then a buckle is applied. Subretinal fluid may or may not need to be released either to restore the intraocular pressure to a normal level or to ensure the break is draped appropriately and accurately over the buckle. If the tear is small and undistorted, a radial buckle is likely to be all that is required (Fig. 13). Multiple tears, tears with rolled edges and big tears are generally not suitable for buckling and are safer managed internally. Circumferential buckles should generally be avoided for horseshoe tears unless the tears are very small (Fig. 14) as they can cause ‘fish-mouthing’ over the buckle [78, 88] resulting in inadequate break closure (Fig. 15). Fish-mouthing occurs due to coronal rather than sagittal scleral shorting. In cases where there is associated scleromalacia at the site of the proposed buckle, the explant may be supported by an encircling band or the case may be managed with PPV.

Detachment secondary to retinal dialysis

Retinal detachment secondary to retinal dialysis presents as a retraction/disinsertion of the retina from the ora serrata. The dialyses often extend over several clock hours and frequently involve over 90° of retina, leading to some being erroneously classified as giant retinal tears (GRT). In contrast to GRTs, the vitreous and posterior hyaloid membrane (PHM) are typically attached in cases of retinal dialysis (Table 1). Traditionally often considered ‘simple’ cases for the vitreoretinal trainee, accurate localisation of the buckle can be more difficult to judge than might be anticipated due to parallax leading to an apparently greater retraction of the break than is actually the case. This can lead the unwary to position the buckle too posteriorly than is required. It can be helpful therefore to localise and mark the apices of the tear (which will be at the ora serrata), and then localise the mid-point as the posterior limit and most can be successfully closed with nothing larger than a 3-mm circumferential sponge. It is also important to ensure the other eye is inspected as there is a 15% incidence of bilateral involvement in non-traumatic dialysis [89].
In a retrospective study done by Kennedy et al., the primary anatomical success rate was 98% surgically [90], and 97% of these patients had scleral buckling procedures. The other 3% of patients had vitrectomy and gas tamponade. Other studies have also shown high success rates of re-attachment from surgical intervention, varying between 96 and 100%, though the actual surgical technique used is not always specified [9193]. In a more recent study, 87% anatomical success rate was achieved in patients after one procedure, and the success rate rose to 97% after two procedures. All of the patients in this study had retinal detachments caused by dialysis and were all treated with circumferential buckles [94].

Retinal detachment secondary to atrophic round holes

Scleral buckling is the approach of choice for retinal detachment secondary to atrophic round retinal holes. Not only does it offer a far higher primary success rate than PPV (which may be challenging as the vitreous and PHM are typically attached), an external approach reduces the risk of secondary nuclear sclerotic cataract. In the largest ever study conducted of retinal detachment secondary to round holes [39], successful re-attachment was achieved in 99% with a single procedure. Multiple round holes were repaired with encircling or circumferential explants, and solitary round holes were repaired with radial buckles. Other papers have also reported similar re-attachment rates after scleral buckling for round holes. In a study conducted by Tillery and Lucier in 1978, the re-attachment rate was 98% [64] and in another study by Greven et al., the initial re-attachment rate was 100% with scleral buckling and cryopexy [95].
In cases with multiple retinal holes in all four quadrants, an encircling band localised over each hole is often the most straightforward approach. The band can be secured with sutures in each quadrant and joined by a Watzke sleeve using a Scott threader allowing correct adjustment of the tension of the band. Where breaks are anterior to the equator of the globe, an important point is to ensure the encirclement lies along a ‘great circle’ of the globe for stability and to avoid postoperative slippage (Fig. 16).

Superior bullous detachments

Conventional scleral buckling may be suitable in selected superior bullous detachments if the tear can be accurately localised, either because the break itself lies in a non-bullous area, or more usually by deploying the D-ACE surgical sequence [86], but usually these cases are more safely managed by an internal approach with vitrectomy and gas tamponade.

Scleral buckles as an adjunct to vitrectomy

For inferior breaks in particular, when a scleral buckle is used in addition to PPV, the success rates are higher than PPV alone [6973]. As with all types of tears, in order to achieve successful re-attachment, break localisation is just as important with PPV as it is with scleral buckling. In the comparative studies comparing PPV alone and PPV combined with SB, an encircling band at the equator is almost always used for buckling [69, 70]. The choice of an encircling buckle arbitrarily deployed at the equator would not be expected to provide any addition benefit unless the tears are also coincidentally located at the equator and so comparative studies do not show higher rates of success when an additional buckle is deployed in this way. The same rules of buckling apply (localisation of break and selecting the correct size and localisation of buckle) even when a buckle is used as an adjunct to vitrectomy.
Another effective use of scleral buckle can be as an adjunct with internal approaches for cases of RRD complicated by PVR. Management of complex PVR is outside the scope of this article, but in such cases, complete dissection and removal of the vitreous and membranes may not always be possible, and circumferential shortening often persists. In such cases, a scleral buckle can be deployed to facilitate apposition of the RPE to neurosensory retina [84, 96100].

Complications of scleral buckling

Although some have argued against scleral buckling due to side effects such as diplopia, strabismus and refractive changes, these are not common complications. Reports of diplopia postsurgery are as low as 2.5% [101] and infection is rare (0.8% [36] to 2% [102]) with careful ‘no touch’ handling of the buckle during surgery and meticulous and accurate closure of the conjunctival/Tenon’s complex.

Conclusion

There is no doubt that PPV has revolutionised and enhanced the successful management of retinal detachment particularly for complex cases, which previously responded poorly to external approaches, particular examples of which include multiple large breaks, giant retinal tears, bullous detachments and cases complicated by PVR. There is danger, however, that increasing dependency on PPV as the sole and only approach for repair of all types of retinal detachment will result in vitreoretinal surgeons and trainees losing (or never acquiring) the skills required for accurate scleral buckling. It remains a simple and highly effective technique for retinal detachment repair, particularly retinal dialyses, round retinal hole detachments and selected cases of retinal detachment associated with horseshoe retinal tears and as an adjunct to vitrectomy. With careful case selection and correct technique, the results can be superior to PPV with reduced comorbidity. Likewise, PPV offers superior results for cases unsuitable for an external approach and careful case selection is key.

Acknowledgements

We thank Mr. Philip Ball (University of Cambridge) for providing us with the schematic drawings that are used in this paper. Also, thanks to the photography department at Addenbrooke’s Hospital for taking and processing the photos taken intraoperatively.

Compliance with ethical standards

This article does not contain any studies with human participants or animals performed by any of the authors.

Conflict of interest

The authors declare that they have no conflict of interest.
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Metadaten
Titel
Scleral buckling—a brief historical overview and current indications
verfasst von
Aijing Wang
Martin P. Snead
Publikationsdatum
11.12.2019
Verlag
Springer Berlin Heidelberg
Erschienen in
Graefe's Archive for Clinical and Experimental Ophthalmology / Ausgabe 3/2020
Print ISSN: 0721-832X
Elektronische ISSN: 1435-702X
DOI
https://doi.org/10.1007/s00417-019-04562-1

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