Erschienen in:
01.05.2007 | Letter to the Editors
Severe anemia caused by the angiotensin receptor blocker irbesartan after renal transplantation
verfasst von:
Giacomo D. Simonetti, Mario G. Bianchetti, Martin Konrad, Rodo O. von Vigier
Erschienen in:
Pediatric Nephrology
|
Ausgabe 5/2007
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Excerpt
Renal transplant recipients are often anemic in the early post-engraftment period because of preexisting anemia exacerbated by perioperative blood loss [
1]. Six or more months after transplantation, anemia is slightly less common, and mostly occurs in the setting of chronic allograft nephropathy associated with reduced glomerular filtration rate [
1]. We report the first pediatric case of anemia after renal transplantation caused by the use of irbesartan, a drug that inhibits the renin-angiotensin II-aldosterone system by blocking the type 1 of angiotensin II receptors [
2‐
5]. …