Erschienen in:
01.06.2007
Sjögren’s Syndrome or Autoimmune Epithelitis?
verfasst von:
H. M. Moutsopoulos
Erschienen in:
Clinical Reviews in Allergy & Immunology
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Ausgabe 3/2007
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Excerpt
Over 30 years ago, I had the opportunity to be Norman Talal’s fellow in the San Francisco University Hospital’s training program. My exposure to patients with Sjögren’s syndrome, among all other patients with systemic autoimmune rheumatic disorders, was unique. Since then, I became a devoted student for understanding the clinical expression and pathogenesis of, and establishing therapeutic intervention for the disorder. The lessons we learned from studying this disease also helped us to understand the pathogenesis of other autoimmune disorders, as well as, why the hyperactive immune system evolves in some patients to B lymphocyte malignancy. The pathogenesis of this disorder in contrast to other autoimmune diseases can be easily evaluated as the affected exocrine glands, the minor labial salivary glands, can be avidly obtained without any major morbidity. …