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22.11.2021 | Original Research

Social Support is Associated with Survival in Patients Diagnosed with Gastrointestinal Cancer

verfasst von: Patrick Bou-Samra, Paul Scott, Hannah Cheng, Cramer Kallem, Ritambhara Pathak, David A. Geller, Wallis Marsh, Yisi Wang, Michael Antoni, Frank Penedo, Allan Tsung, Jennifer L. Steel

Erschienen in: Journal of Gastrointestinal Cancer | Ausgabe 4/2022

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Abstract

Purpose

The aim of this study was to examine the link between psychological, behavioral, and social factors and survival in patients diagnosed with gastrointestinal cancer.

Methods

A cohort of gastrointestinal cancer patients were administered a battery of questionnaires that assessed trauma, depression, social support, sleep, diet, exercise, quality of life, tobacco and alcohol use, pain, and fatigue. Analyses included Pearson’s correlations, analyses of variance, Kaplan Meier survival, and Cox regression analyses.

Results

Of the 568 patients, the majority were male (57.9%) and Caucasian (91.9%), with a mean age of 61 (S.D. = 10.7). The level of perceived social support was comparable to patients with other medical conditions. Sociodemographic predictors of social support included the number of years of education (r = 0.109, p = 0.05), marital status (F(6,387) = 5.465, p ≤ 0.001), and whether the patients’ income met the family’s basic needs (F(1,377) = 25.531, p < 0.001). Univariate analyses revealed that older age (p < 0.001), male gender (p = 0.007), being black (p = 0.005), diagnosis of hepatocellular carcinoma (p = 0.046), higher body mass index (p = 0.022), larger tumor size (p = 0.032), initial treatment including chemotherapy rather than surgery (p < 0.001), and lower level of perceived social support (p = 0.037) were associated with poorer survival. Using multivariate Cox regression and adjusting for all factors found to be significant in univariate survival analyses, older age (p = 0.024) and lower perceived social support (HR = 0.441, 95% CI = 0.233, 0.833; p = 0.012) were the factors that remained significantly associated with poorer survival.

Conclusion

There are several biological and psychosocial factors that predict cancer mortality. Social support appears to be a robust factor affecting mortality in gastrointestinal cancer patients.

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Titel: Social Support is Associated with Survival in Patients Diagnosed with Gastrointestinal Cancer
verfasst von: Patrick Bou-Samra
Paul Scott
Hannah Cheng
Cramer Kallem
Ritambhara Pathak
David A. Geller
Wallis Marsh
Yisi Wang
Michael Antoni
Frank Penedo
Allan Tsung
Jennifer L. Steel
Publikationsdatum: 22.11.2021
Verlag: Springer US
Erschienen in: Journal of Gastrointestinal Cancer / Ausgabe 4/2022
Print ISSN: 1941-6628
Elektronische ISSN: 1941-6636
DOI: https://doi.org/10.1007/s12029-021-00741-8

Springer Medizin

Social Support is Associated with Survival in Patients Diagnosed with Gastrointestinal Cancer