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European Journal of Nutrition

Erschienen in:

01.04.2010 | Original Contribution

Soybean whey enhance mineral balance and caecal fermentation in rats

verfasst von: María Dolores Tenorio, Irene Espinosa-Martos, Guadalupe Préstamo, Pilar Rupérez

Erschienen in: European Journal of Nutrition | Ausgabe 3/2010

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Abstract

Background

Soybean whey, a by-product of tofu manufacturing, is currently discarded by the food industry. However, it contains valuable compounds such as non-digestible oligosaccharides (NDO), which promote the growth of beneficial lactic acid bacteria in the colon, and are therefore recognized as prebiotics. Acidic fermentation of NDO in the caecum appears to be related with an increase in mineral absorption.

Aim of the study

To evaluate the effect of consuming soybean whey containing galacto-oligosaccharides (GOS) on mineral absorption and caecal fermentation in rats.

Methods

An in vivo assay was carried out in rats over a period of 4 weeks; previously, the nutritional composition of soybean whey was determined and NDO were measured by high-performance liquid chromatography (HPLC). Faeces and urine were collected weekly throughout the experiment for mineral balance analyses. Animals were killed under anaesthesia, organs were removed and weighed, and short-chain fatty acids in the caecal contents were determined by gas chromatography.

Results and conclusions

Non-digestible carbohydrates such as GOS stachyose (318 ± 3 mg/100 mL) and traces of inulin were identified by HPLC. When soybean whey was used as a source of GOS in rats, the consumption of diluted soybean whey (75 mL/day per rat) containing GOS (120 mg/day per rat) exhibited a prebiotic effect and led to an improved mineral balance, especially for calcium and magnesium. In view of its composition and potential health-promoting properties, soybean whey could be used as a valuable ingredient in new functional foods.

Asvarujanon P, Ishizuka S, Hara H (2005) Promotive effects of non-digestible disaccharides on rat mineral absorption depends on the type of saccharide. Nutrition 21:1025–1035CrossRef

Chonan O, Takahashi R, Watanuki M (2001) Role of activity of gastrointestinal microflora in absorption of calcium and magnesium in rats fed β1-4-linked galacto-oligosaccharides. Biosci Biotechnol Biochem 65:1872–1875CrossRef

Coudray C, Demigné C, Raissiguier Y (2003) Effects of dietary fibers on magnesium absorption in animals and humans. J Nutr 133:1–4

Coudray C, Tressol JC, Gueux E, Thien S, Jaffrelo L, Mazur A, Rayssiguier Y (2005) Stimulatory effect of inulin on intestinal absorption of calcium and magnesium in rats is modulated by dietary calcium intakes. Short- and long-term balance studies. Eur J Nutr 44:293–302CrossRef

Delzenne N, Aertssens J, Verplaetse H, Roccaro M, Roberfroid M (1995) Effect of fermentable fructo-oligosaccharides on mineral nitrogen and energy digestive balance in the rat. Life Sci 57:1579–1587CrossRef

Espinosa-Martos I, Préstamo G, Rupérez P (2006) Composición y propiedades del suero de soja, un subproducto de la elaboración del tofu. Alimentaria 371:72–73

Fuller R, Gibson GR (1997) Modification of the intestinal microflora using probiotics and prebiotics. Scand J Gastroenterol Suppl 222:28–31

García-Domingo C, Rupérez P, Saura-Calixto F (1997) Indigestible fraction and starch availability in peas measured in vitro. Z Lebens Unters Forsch 205:43–47CrossRef

Gibson GR, Roberfroid MB (1995) Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J Nutr 125:1401–1412

10.

Grieshop CM, Kadzere CT, Clapper GM, Flickinger EA, Bauer LL, Frazier RL, Fahey GC Jr (2003) Chemical and nutritional characteristics of United States soybeans and soybean meals. J Agric Food Chem 51:7684–7691CrossRef

11.

Hardwick LL, Jones MR, Brautbar N, Lee DB (1991) Magnesium absorption: mechanisms and the influence of vitamin D, calcium and phosphate. J Nutr 121:13–23

12.

Jiménez-Escrig A, Tenorio MD, Espinosa-Martos I, Rupérez P (2008) Health-promoting effects of a dietary fiber concentrate from the soybean byproduct okara in rats. J Agric Food Chem 56:7495–7501CrossRef

13.

Kashimura J, Kimura M, Itokawa Y (1996) The effects of isomaltulose, isomalt, and isomaltulose-based oligomers on mineral absorption and retention. Biol Trace Elem Res 54:239–250CrossRef

14.

Koga Y, Shibuta T, O’Brien R (1993) Soybean oligosaccharides. In: Nakakuki T (ed) Oligosaccharides. Production, properties and applications. Japan Technology Review Section E: Biotechnology vol 3, no 2. Gordon and Breach Science Publishers, Switzerland, pp 175–203

15.

Levrat MA, Behr SR, Rèmèsy C, Demigné C (1991) Effects of soybean fiber on caecal digestion in rats previously adapted to a fiber-free diet. J Nutr 121:672–678

16.

Liu KS (1999) Chemistry and nutritional value of soybean components. In: Soybeans: chemistry, technology and utilization. Aspen, Gaithersburg, pp 25–113

17.

Liu KS (1999) Nonfermented oriental soyfoods. In Soybeans: chemistry, technology and utilization. Aspen, Gaithersburg, pp 137–217

18.

Loewus FA (1952) Improvement in the anthrone method for determination of carbohydrates. Anal Chem 24:219CrossRef

19.

López HW, Coudray C, Levrat-Verny MA, Feillet-Coudray C, Demigné C, Rèmèsy C (2000) Fructo-oligosaccharides enhance mineral apparent absorption and counteract the deleterious effects of phytic acid on mineral homeostasis in rats. J Nutr Biochem 11:500–508CrossRef

20.

Lupton JR, Kurtz PP (1993) Relationship of colonic luminal short-chain fatty acids and pH to in vivo cell proliferation in rats. J Nutr 123:1522–1530

21.

Mañas E, Saura-Calixto F (1993) Ethanolic precipitation: a source of error in dietary fibre determination. Food Chem 47:351–355CrossRef

22.

Marcfalane GT, Steed H, Marcfalane S (2008) Bacterial metabolism and health-related effects of galacto-oligosaccharides and other prebiotics. J Appl Microbiol 104:305–344

23.

Mitamura R, Hara H, Aoyama Y (2004) Ingestion of raffinose promotes calcium absorption in the large intestine of rats. Biosci Biotechnol Biochem 68:384–389CrossRef

24.

Ohta A, Ohtsuki M, Baba S, Hirayama M, Adachi T (1998) Comparison of the nutritional effects of fructo-oligosaccharides of different sugar chain length in rats. Nutr Res 18:109–120CrossRef

25.

Ohta A, Ohtsuki M, Takizawa T, Inaba H, Adachi T, Kimura S (1994) Effects of fructo-oligosaccharides on the absorption of magnesium and calcium in cecectomized rats. Int J Vitam Nutr Res 64:316–324

26.

Préstamo G, Rupérez P, Espinosa-Martos I, Villanueva MJ, Lasunción MA (2007) The effects of okara on rat growth, caecal fermentation, and serum lipids. Eur Food Res Technol 225:925–928CrossRef

27.

Prosky L, Asp N-G, Schweizer TF, De Vries JW, Furda I (1988) Determination of insoluble, soluble and total dietary fibre in foods and food products: interlaboratory study. J Assoc Off Anal Chem 71:1017–1023

28.

Raschka L, Daniel H (2005) Diet composition and age determine the effects of inulin-type fructans on intestinal calcium absorption in rat. Eur J Nutr 44:360–364CrossRef

29.

Raschka L, Daniel H (2005) Mechanism underlying the effects of inulin-type fructans on calcium absorption in the large intestine of rats. Bone 37:728–735CrossRef

30.

Rèmèsy C, Levrat MA, Gamet L, Demigné C (1993) Caecal fermentations in rats fed oligosaccharides (inulin) are modulated by dietary calcium level. Am J Physiol 264:855–862

31.

Roberfroid M, Slavin J (2000) Nondigestible oligosaccharides. Crit Rev Food Sci Nutr 40:461–480CrossRef

32.

Rupérez P (1998) Oligosaccharides in raw and processed legumes. Z Lebensm Unters Forsch 206:130–133CrossRef

33.

Sako T, Matsumoto K, Tanaka R (1999) Recent progress on research and application of non-digestible galacto-oligosaccharides. Int Dairy J 9:69–80CrossRef

34.

Schulz AGM, Amelsvoort JMM, Beynen AC (1993) Dietary native resistant starch but not retrograded resistant starch raises magnesium and calcium absorption in rats. J Nutr 123:1724–1731

35.

Scott RW (1979) Colorimetric determination of hexuronic acids in plant materials. Anal Chem 51:936–941CrossRef

36.

Tomomatsu H (1994) Health effects of oligosaccharides. Food Technol 48:61–65

37.

Tortuero F, Fernández E, Rupérez P, Moreno M (1997) Raffinose and lactic acid bacteria influence caecal fermentation and serum cholesterol in rats. Nutr Res 17:41–49CrossRef

38.

Trinidad P-T, Wolever TMS, Thompson LU (1993) Interactive effects of Ca and short chain fatty acid on absorption in the distal colon of man. Nutr Res 13:417–425CrossRef

39.

van Loo J, Coussement P, De Leenheer L, Hoebregs H, Smits G (1995) On the presence of inulin and oligofructose as natural ingredients in the Western diet. Crit Rev Food Sci Nutr 35:525–552CrossRef

40.

Wolf BW, Firkins JL, Xiaosong Zhang MS (1998) Varying dietary concentrations of fructo-oligosaccharides affect apparent absorption and balance of minerals in growing rats. Nutr Res 18:1791–1806CrossRef

41.

Younes H, Demigné C, Rèmèsy C (1996) Acidic fermentation in the caecum increases absorption of calcium and magnesium in the large intestine of the rat. Br J Nutr 75:301–314CrossRef

42.

Zafar TA, Weaver CM, Zhao Y, Martín BR, Wasteney ME (2004) Nondigestible oligosaccharides increase calcium absorption and suppress bone resorption in ovariectomized rats. J Nutr 134(2):399–402

Titel: Soybean whey enhance mineral balance and caecal fermentation in rats
verfasst von: María Dolores Tenorio
Irene Espinosa-Martos
Guadalupe Préstamo
Pilar Rupérez
Publikationsdatum: 01.04.2010
Verlag: Springer-Verlag
Erschienen in: European Journal of Nutrition / Ausgabe 3/2010
Print ISSN: 1436-6207
Elektronische ISSN: 1436-6215
DOI: https://doi.org/10.1007/s00394-009-0060-8

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Abstract

Background

Aim of the study

Methods

Results and conclusions

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