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Breast Cancer Research and Treatment

Ausgabe 2/2012

Inhalt (45 Artikel)

Review

Adjuvant bisphosphonate treatment for breast cancer: Why did something so elegant become so complicated?

Mark Clemons, Kent Russell, Luis Costa, Christina L. Addison

Review

Adherence to adjuvant hormonal therapy among breast cancer survivors in clinical practice: a systematic review

Caitlin C. Murphy, L. Kay Bartholomew, Melissa Y. Carpentier, Shirley M. Bluethmann, Sally W. Vernon

Review

Fruits, vegetables and breast cancer risk: a systematic review and meta-analysis of prospective studies

D. Aune, D. S. M. Chan, A. R. Vieira, D. A. Navarro Rosenblatt, R. Vieira, D. C. Greenwood, T. Norat

Preclinical Study

Pre-clinical studies of Notch signaling inhibitor RO4929097 in inflammatory breast cancer cells

Bisrat G. Debeb, Evan N. Cohen, Kimberly Boley, Erik M. Freiter, Li Li, Fredika M. Robertson, James M. Reuben, Massimo Cristofanilli, Thomas A. Buchholz, Wendy A. Woodward

Preclinical Study

Fatty acid binding protein 7 expression and its sub-cellular localization in breast cancer

Alaa T. Alshareeda, Emad A. Rakha, Christopher C. Nolan, Ian O. Ellis, Andrew R. Green

Preclinical Study

SGK3 is associated with estrogen receptor expression in breast cancer

Jun Xu, Ma Wan, Quanyuan He, Roland L. Bassett Jr, Xiaoyong Fu, Albert C. Chen, Fengtao Shi, Chad J. Creighton, Rachel Schiff, Lei Huo, Dan Liu

Preclinical Study

Analysis of KLLN as a high-penetrance breast cancer predisposition gene

Ella R. Thompson, Kylie L. Gorringe, David Y. H. Choong, Diana M. Eccles, Gillian Mitchell, Ian G. Campbell

Preclinical Study

Low expression of ULK1 is associated with operable breast cancer progression and is an adverse prognostic marker of survival for patients

Jun Tang, Rong Deng, Rong-Zhen Luo, Guo-Ping Shen, Mu-Yan Cai, Zi-Ming Du, Shan Jiang, Ming-Tian Yang, Jian-Hua Fu, Xiao-Feng Zhu

Preclinical study

Rare oncogenic mutations of predictive markers for targeted therapy in triple-negative breast cancer

Tobias J. Grob, Uwe Heilenkötter, Stefan Geist, Peter Paluchowski, Christian Wilke, Fritz Jaenicke, Alexander Quaas, Waldemar Wilczak, Matthias Choschzick, Guido Sauter, Annette Lebeau

Preclinical study

Estrogen receptor beta binds Sp1 and recruits a corepressor complex to the estrogen receptor alpha gene promoter

V. Bartella, P. Rizza, I. Barone, D. Zito, F. Giordano, C. Giordano, S. Catalano, L. Mauro, D. Sisci, M. L. Panno, S. A. W. Fuqua, S. Andò

Preclinical Study

Upregulation of mucin4 in ER-positive/HER2-overexpressing breast cancer xenografts with acquired resistance to endocrine and HER2-targeted therapies

Albert C. Chen, Ilenia Migliaccio, Mothaffar Rimawi, Sara Lopez-Tarruella, Chad J. Creighton, Suleiman Massarweh, Catherine Huang, Yen-Chao Wang, Surinder K. Batra, M. Carolina Gutierrez, C. Kent Osborne, Rachel Schiff

Preclinical Study

Mechanisms of cardiotoxicity associated with ErbB2 inhibitors

Carmine Fedele, Gennaro Riccio, Angela Eliana Malara, Giuseppe D’Alessio, Claudia De Lorenzo

Open Access Preclinical Study

Therapeutic potential for phenytoin: targeting Nav1.5 sodium channels to reduce migration and invasion in metastatic breast cancer

Ming Yang, David J. Kozminski, Lindsey A. Wold, Rohan Modak, Jeffrey D. Calhoun, Lori L. Isom, William J. Brackenbury

Open Access Preclinical study

Assessing HER2 amplification in breast cancer: findings from the Australian In Situ Hybridization Program

Michael Bilous, Adrienne L. Morey, Jane E. Armes, Richard Bell, Peter H. Button, Margaret C. Cummings, Stephen B. Fox, Glenn D. Francis, Brigid Waite, Glenda McCue, Wendy A. Raymond, Peter D. Robbins, Gelareh Farshid

Preclinical Study

Specific transcriptional response of four blockers of estrogen receptors on estradiol-modulated genes in the mouse mammary gland

Ezequiel Calvo, Van Luu-The, Pascal Belleau, Céline Martel, Fernand Labrie

Preclinical study

Differential anti-proliferative activities of poly(ADP-ribose) polymerase (PARP) inhibitors in triple-negative breast cancer cells

Hsiao-Ching Chuang, Naval Kapuriya, Samuel K. Kulp, Ching-Shih Chen, Charles L. Shapiro

Preclinical Study

Predictions of the pathological response to neoadjuvant chemotherapy in patients with primary breast cancer using a data mining technique

M. Takada, M. Sugimoto, S. Ohno, K. Kuroi, N. Sato, H. Bando, N. Masuda, H. Iwata, M. Kondo, H. Sasano, L. W. C. Chow, T. Inamoto, Y. Naito, M. Tomita, M. Toi

Clinical Trial

Prognostic value of biologic subtype and the 21-gene recurrence score relative to local recurrence after breast conservation treatment with radiation for early stage breast carcinoma: results from the Eastern Cooperative Oncology Group E2197 study

Lawrence J. Solin, Robert Gray, Lori J. Goldstein, Abram Recht, Frederick L. Baehner, Steven Shak, Sunil Badve, Edith A. Perez, Lawrence N. Shulman, Silvana Martino, Nancy E. Davidson, George W. Sledge Jr., Joseph A. Sparano

Open Access Clinical trial

Tissue distribution of 4-hydroxy-N-desmethyltamoxifen and tamoxifen-N-oxide

Jennifer Gjerde, Sara Gandini, Aliana Guerrieri-Gonzaga, Line L. Haugan Moi, Valentina Aristarco, Gunnar Mellgren, Andrea DeCensi, Ernst A. Lien

Clinical Trial

Expression of activated type I receptor tyrosine kinases in early breast cancer

Melanie Spears, Hans Christian Pederson, Nicola Lyttle, Claire Gray, Mary Anne Quintayo, Lyndsay Brogan, Jeremy St. J Thomas, Gillian R. Kerr, Wilma J. L. Jack, Ian H. Kunkler, David A. Cameron, Udi Chetty, John M. S. Bartlett

Clinical Trial

Increased prevalence of vitamin D insufficiency in patients with breast cancer after neoadjuvant chemotherapy

William Jacot, Stéphane Pouderoux, Simon Thezenas, Angélique Chapelle, Jean-Pierre Bleuse, Gilles Romieu, Pierre-Jean Lamy

Clinical Trial

Early breast cancer with positive margins: excellent local control with an upfront brachytherapy boost

Thomas M. Schroeder, Ben Liem, Sagus Sampath, William R. Thompson, Janet Longhurst, Melanie Royce

Clinical Trial

Weight change associated with anastrozole and tamoxifen treatment in postmenopausal women with or at high risk of developing breast cancer

Ivana Sestak, Michelle Harvie, Anthony Howell, John F. Forbes, Mitch Dowsett, Jack Cuzick

Open Access Clinical trial

Sentinel lymph node biopsy of the internal mammary chain in breast cancer

E. L. Postma, S. van Wieringen, M. G. Hobbelink, H. M. Verkooijen, H. J. G. D. van den Bongard, I. H. M. Borel Rinkes, A. J. Witkamp

Clinical trial

TOP2A RNA expression and recurrence in estrogen receptor-positive breast cancer

Joseph A. Sparano, Lori J. Goldstein, Nancy E. Davidson, George W. Sledge Jr., Robert Gray

Clinical Trial

Feasibility of a randomized controlled trial of vitamin D vs. placebo in women with recently diagnosed breast cancer

David W. Cescon, Patricia A. Ganz, Samantha Beddows, Marguerite Ennis, Barbara K. Mills, Pamela J. Goodwin

Epidemiology

Body size and breast cancer prognosis in relation to hormone receptor and menopausal status: a meta-analysis

Saroj Niraula, Alberto Ocana, Marguerite Ennis, Pamela J. Goodwin

Epidemiology

Adolescent intakes of vitamin D and calcium and incidence of proliferative benign breast disease

Xuefen Su, Graham A. Colditz, Laura C. Collins, Heather J. Baer, Laura A. Sampson, Walter C. Willett, Catherine S. Berkey, Stuart J. Schnitt, James L. Connolly, Bernard A. Rosner, Rulla M. Tamimi

Epidemiology

Prognostic implications of estrogen receptor pattern of both tumors in contralateral breast cancer

Maria E. C. Sandberg, Mikael Hartman, Daniel Klevebring, Sandra Eloranta, Alexander Ploner, Per Hall, Kamila Czene

Epidemiology

Examination of ancestral informative markers and self-reported race with tumor characteristics of breast cancer among black and white women

Kerryn W. Reding, Christopher S. Carlson, Orsalem Kahsai, Christina C. Chen, Andrew McDavid, David R. Doody, Chu Chen, India Ornelas, Kimberly Lowe, Leslie Bernstein, Linda Weiss, Jill A. McDonald, Michael S. Simon, Brian Strom, Polly A. Marchbanks, Ronald Burkman, Robert Spirtas, Jonathan M. Liff, Kathleen E. Malone

Epidemiology

Serum cotinine and prognosis in breast cancer

L. Johnson, O. Agbaje, M. Doig, I. S. Fentiman

Epidemiology

The economic burden of metastatic breast cancer: a U.S. managed care perspective

Alberto J. Montero, Sara Eapen, Brian Gorin, Paulette Adler

Open Access Epidemiology

Adult weight gain, fat distribution and mammographic density in Spanish pre- and post-menopausal women (DDM-Spain)

Marina Pollán, Virginia Lope, Josefa Miranda-García, Milagros García, Francisco Casanova, Carmen Sánchez-Contador, Carmen Santamariña, Pilar Moreo, Carmen Vidal, Mercé Peris, María Pilar Moreno, José Antonio Vázquez-Carrete, Francisca Collado, Carmen Pedraz-Pingarrón, Nieves Ascunce, Dolores Salas-Trejo, Nuria Aragonés, Beatriz Pérez-Gómez, Francisco Ruiz-Perales

Epidemiology

Incidence of invasive breast cancer in the presence of competing mortality: the Canadian National Breast Screening Study

Sharareh Taghipour, Dragan Banjevic, Joanne Fernandes, Anthony B. Miller, Neil Montgomery, Bart J. Harvey, Andrew K. S. Jardine

Epidemiology

Long-term survival of older breast cancer patients: population-based estimates over three decades

Bindu Kanapuru, William B. Ershler, Charles Hesdorffer, Ahmedin Jemal, Jerome W. Yates

Epidemiology

The influence of mammographic density on breast tumor characteristics

Louise Eriksson, Kamila Czene, Lena Rosenberg, Keith Humphreys, Per Hall

Epidemiology

The influence of non-clinical patient factors on medical oncologists’ decisions to recommend breast cancer adjuvant chemotherapy

T. May Pini, Sarah T. Hawley, Yun Li, Steven J. Katz, Jennifer J. Griggs

Brief Report

Use of tamoxifen and raloxifene for breast cancer chemoprevention in 2010

Erika A. Waters, Timothy S. McNeel, Worta McCaskill Stevens, Andrew N. Freedman

Brief Report

NSAID analgesic ketorolac used perioperatively may suppress early breast cancer relapse: particular relevance to triple negative subgroup

Michael Retsky, Rick Rogers, Romano Demicheli, William JM Hrushesky, Isaac Gukas, Jayant S. Vaidya, Michael Baum, Patrice Forget, Marc DeKock, Katharina Pachmann

Brief Report

Recurrent BRCA1 and BRCA2 mutations in breast cancer patients of African ancestry

Jing Zhang, James D. Fackenthal, Yonglan Zheng, Dezheng Huo, Ningqi Hou, Qun Niu, Cecilia Zvosec, Temidayo O. Ogundiran, Anselm J. Hennis, Maria Cristina Leske, Barbara Nemesure, Suh-Yuh Wu, Olufunmilayo I. Olopade

Letter to the Editor

High sensitivity for BRCA1/2 mutations in breast/ovarian kindreds: are there still other breast/ovary genes to be discovered?

Miriam J. Smith, Franchesca L. Gifford, Fiona Lalloo, William G. Newman, D. Gareth R. Evans

Letter to the Editor

A bias in genotyping the miR-27a rs895819 and rs11671784 variants

Rongxi Yang, Barbara Burwinkel

Umsetzung der POMGAT-Leitlinie läuft

03.05.2024 DCK 2024 Kongressbericht

Seit November 2023 gibt es evidenzbasierte Empfehlungen zum perioperativen Management bei gastrointestinalen Tumoren (POMGAT) auf S3-Niveau. Vieles wird schon entsprechend der Empfehlungen durchgeführt. Wo es im Alltag noch hapert, zeigt eine Umfrage in einem Klinikverbund.

CUP-Syndrom: Künstliche Intelligenz kann Primärtumor finden

30.04.2024 Künstliche Intelligenz Nachrichten

Krebserkrankungen unbekannten Ursprungs (CUP) sind eine diagnostische Herausforderung. KI-Systeme können Pathologen dabei unterstützen, zytologische Bilder zu interpretieren, um den Primärtumor zu lokalisieren.

Sind Frauen die fähigeren Ärzte?

30.04.2024 Gendermedizin Nachrichten

Patienten, die von Ärztinnen behandelt werden, dürfen offenbar auf bessere Therapieergebnisse hoffen als Patienten von Ärzten. Besonders gilt das offenbar für weibliche Kranke, wie eine Studie zeigt.

Adjuvante Immuntherapie verlängert Leben bei RCC

25.04.2024 Nierenkarzinom Nachrichten

Nun gibt es auch Resultate zum Gesamtüberleben: Eine adjuvante Pembrolizumab-Therapie konnte in einer Phase-3-Studie das Leben von Menschen mit Nierenzellkarzinom deutlich verlängern. Die Sterberate war im Vergleich zu Placebo um 38% geringer.

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