Ausgabe 6/2018
Inhalt (9 Artikel)
Open Access
Review Article
Clinical Pharmacokinetic and Pharmacodynamic Profile of Riociguat
Reiner Frey, Corina Becker, Soundos Saleh, Sigrun Unger, Dorina van der Mey, Wolfgang Mück
Open Access
Review Article
Vortioxetine: Clinical Pharmacokinetics and Drug Interactions
Grace Chen, Astrid-Maria Højer, Johan Areberg, George Nomikos
Review Article
Antibody–Drug Conjugates: Pharmacokinetic/Pharmacodynamic Modeling, Preclinical Characterization, Clinical Studies, and Lessons Learned
William D. Hedrich, Tamer E. Fandy, Hossam M. Ashour, Hongbing Wang, Hazem E. Hassan
Open Access
Original Research Article
Prediction of Fetal Darunavir Exposure by Integrating Human Ex-Vivo Placental Transfer and Physiologically Based Pharmacokinetic Modeling
Stein Schalkwijk, Aaron O. Buaben, Jolien J. M. Freriksen, Angela P. Colbers, David M. Burger, Rick Greupink, Frans G. M. Russel
Open Access
Original Research Article
Population Pharmacokinetic and Pharmacodynamic Analysis of Belimumab Administered Subcutaneously in Healthy Volunteers and Patients with Systemic Lupus Erythematosus
Herbert Struemper, Mita Thapar, David Roth
Original Research Article
Effects of the Proton Pump Inhibitors Omeprazole and Pantoprazole on the Cytochrome P450-Mediated Metabolism of Venlafaxine
Maxim Kuzin, Georgios Schoretsanitis, Ekkehard Haen, Benedikt Stegmann, Christoph Hiemke, Gerhard Gründer, Michael Paulzen
Original Research Article
Population Pharmacokinetics of Stiripentol in Paediatric Patients with Dravet Syndrome Treated with Stiripentol, Valproate and Clobazam Combination Therapy
Sophie Peigné, Stéphanie Chhun, Michel Tod, Elisabeth Rey, Christelle Rodrigues, Catherine Chiron, Gérard Pons, Vincent Jullien
Original Research Article
A Physiologically Based Pharmacokinetic Model for Pregnant Women to Predict the Pharmacokinetics of Drugs Metabolized Via Several Enzymatic Pathways
André Dallmann, Ibrahim Ince, Katrin Coboeken, Thomas Eissing, Georg Hempel