Ausgabe 4/2017
Inhalt (14 Artikel)
Impact of Site Selection and Study Conduct on Outcomes in Global Clinical Trials
Chaudhry M. S. Sarwar, Muthiah Vaduganathan, Javed Butler
Novel Endpoints for Heart Failure Clinical Trials
Carine E. Hamo, Mihai Gheorghiade, Javed Butler
Designing Future Clinical Trials in Heart Failure With Preserved Ejection Fraction: Lessons From TOPCAT
Ravi B. Patel, Sanjiv J. Shah, Gregg C. Fonarow, Javed Butler, Muthiah Vaduganathan
Towards Holistic Heart Failure Management—How to Tackle the Iron Deficiency Epidemic?
Lucas N. L. Van Aelst, Dominiek Mazure, Alain Cohen-Solal
From Inflammation to Fibrosis—Molecular and Cellular Mechanisms of Myocardial Tissue Remodelling and Perspectives on Differential Treatment Opportunities
Navin Suthahar, Wouter C. Meijers, Herman H.W. Silljé, Rudolf A. de Boer
Inflammation – Cause or Consequence of Heart Failure or Both?
Sophie Van Linthout, Carsten Tschöpe
Treatment of Hyperkalemia in Heart Failure
Ersilia M. DeFilippis, Akshay S. Desai
Role of SGLT2 Inhibitors in Patients with Diabetes Mellitus and Heart Failure
Frederik H. Verbrugge
Biomarkers in Sleep Apnea and Heart Failure
Ying Y. Zhao, Reena Mehra
Novel Biomarkers of Subclinical Cardiac Dysfunction in the General Population
Kamal Shemisa, Anish Bhatt, Daniel Cheeran, Ian J. Neeland
The Basic Metabolic Profile in Heart Failure—Marker and Modifier
Ahmed Elfar, Kamalanathan K. Sambandam
Therapeutic Strategies Targeting Inherited Cardiomyopathies
Kenneth Varian, W. H. Wilson Tang
SGLT-2 Inhibitors in Heart Failure: Implications for the Kidneys
Frederik H. Verbrugge, Pieter Martens, Wilfried Mullens
Targeting Mitochondrial Calcium Handling and Reactive Oxygen Species in Heart Failure
Alexander Dietl, Christoph Maack