Ausgabe 8/2015
Inhalt (37 Artikel)
Diabetologia at 50: celebrating half a century of progress in diabetes research and care
Juleen R. Zierath
Hepatokines: unlocking the multi-organ network in metabolic diseases
Alison Iroz, Jean-Pierre Couty, Catherine Postic
The future of brown adipose tissues in the treatment of type 2 diabetes
Patrick Schrauwen, Wouter D. van Marken Lichtenbelt, Bruce M. Spiegelman
50 years forward: mechanisms of hyperglycaemia-driven diabetic complications
Nicholas D. F. Russell, Mark E. Cooper
Vascular AGE-ing by methylglyoxal: the past, the present and the future
Casper G. Schalkwijk
The erosion of physical activity in Western societies: an economic death march
Frank W. Booth, John A. Hawley
Medications for type 2 diabetes: how will we be treating patients in 50 years?
Steven E. Kahn, John B. Buse
Incretin-based therapies: where will we be 50 years from now?
Juris J. Meier, Michael A. Nauck
GIP increases adipose tissue expression and blood levels of MCP-1 in humans and links high energy diets to inflammation: a randomised trial
Özlem Gögebakan, Martin A. Osterhoff, Rita Schüler, Olga Pivovarova, Michael Kruse, Anne-Cathrin Seltmann, Alexander S. Mosig, Natalia Rudovich, Michael Nauck, Andreas F. H. Pfeiffer
Effects of exogenous glucagon-like peptide-1 on blood pressure, heart rate, gastric emptying, mesenteric blood flow and glycaemic responses to oral glucose in older individuals with normal glucose tolerance or type 2 diabetes
Laurence G. Trahair, Michael Horowitz, Julie E. Stevens, Christine Feinle-Bisset, Scott Standfield, Diana Piscitelli, Christopher K. Rayner, Adam M. Deane, Karen L. Jones
All-cause mortality in a nationwide cohort of childhood-onset diabetes in Norway 1973–2013
Vibeke Gagnum, Lars C. Stene, Leiv Sandvik, Morten W. Fagerland, Pål R. Njølstad, Geir Joner, Torild Skrivarhaug
OGTT and random plasma glucose in the prediction of type 1 diabetes and time to diagnosis
Olli Helminen, Susanna Aspholm, Tytti Pokka, Jorma Ilonen, Olli Simell, Riitta Veijola, Mikael Knip
Inverse association between fasting plasma glucose and risk of ventricular arrhythmias
Francesco Zaccardi, David R. Webb, Sudhir Kurl, Kamlesh Khunti, Melanie J. Davies, Jari A. Laukkanen
Delta cell death in the islet of Langerhans and the progression from normal glucose tolerance to type 2 diabetes in non-human primates (baboon, Papio hamadryas)
Rodolfo Guardado Mendoza, Carla Perego, Giovanna Finzi, Stefano La Rosa, Carlo Capella, Lilia M. Jimenez-Ceja, Licio A. Velloso, Mario J. A. Saad, Fausto Sessa, Federico Bertuzzi, Stefania Moretti, Edward J. Dick Jr., Alberto M. Davalli, Franco Folli
Involvement of long non-coding RNAs in beta cell failure at the onset of type 1 diabetes in NOD mice
Anna Motterle, Sonia Gattesco, Dorothée Caille, Paolo Meda, Romano Regazzi
The FOXP1, FOXP2 and FOXP4 transcription factors are required for islet alpha cell proliferation and function in mice
Jason M. Spaeth, Chad S. Hunter, Lauren Bonatakis, Min Guo, Catherine A. French, Ian Slack, Manami Hara, Simon E. Fisher, Jorge Ferrer, Edward E. Morrisey, Ben Z. Stanger, Roland Stein
Type 2 diabetes alters metabolic and transcriptional signatures of glucose and amino acid metabolism during exercise and recovery
Jakob S. Hansen, Xinjie Zhao, Martin Irmler, Xinyu Liu, Miriam Hoene, Mika Scheler, Yanjie Li, Johannes Beckers, Martin Hrabĕ de Angelis, Hans-Ulrich Häring, Bente K. Pedersen, Rainer Lehmann, Guowang Xu, Peter Plomgaard, Cora Weigert
A systems view of type 2 diabetes-associated metabolic perturbations in saliva, blood and urine at different timescales of glycaemic control
Noha A. Yousri, Dennis O. Mook-Kanamori, Mohammed M. El-Din Selim, Ahmed H. Takiddin, Hala Al-Homsi, Khoulood A. S. Al-Mahmoud, Edward D. Karoly, Jan Krumsiek, Kieu Thinh Do, Ulrich Neumaier, Marjonneke J. Mook-Kanamori, Jillian Rowe, Omar M. Chidiac, Cindy McKeon, Wadha A. Al Muftah, Sara Abdul Kader, Gabi Kastenmüller, Karsten Suhre
Oncostatin M is a potential agent for the treatment of obesity and related metabolic disorders: a study in mice
Tadasuke Komori, Minoru Tanaka, Hiroto Furuta, Takashi Akamizu, Atsushi Miyajima, Yoshihiro Morikawa
Insulin regulates Rab3–Noc2 complex dissociation to promote GLUT4 translocation in rat adipocytes
Francoise Koumanov, Vinit J. Pereira, Judith D. Richardson, Samantha L. Sargent, Daniel J. Fazakerley, Geoffrey D. Holman
Intestinal mTOR regulates GLP-1 production in mouse L cells
Geyang Xu, Ziru Li, Li Ding, Hong Tang, Song Guo, Hongbin Liang, Huadong Wang, Weizhen Zhang
Infrared thermographic assessment of changes in skin temperature during hypoglycaemia in patients with type 1 diabetes
Anne-Sophie Sejling, Kai H. W. Lange, Christian S. Frandsen, Sarah S. Diemar, Lise Tarnow, Jens Faber, Jens J. Holst, Bolette Hartmann, Linda Hilsted, Troels W. Kjaer, Claus B. Juhl, Birger Thorsteinsson, Ulrik Pedersen-Bjergaard
Insulin-induced changes in skeletal muscle microvascular perfusion are dependent upon perivascular adipose tissue in women
Rick I. Meijer, Erik H. Serné, H. Ibrahim Korkmaz, Donald L. van der Peet, Michiel P. de Boer, Hans W. M. Niessen, Victor W. M. van Hinsbergh, John S. Yudkin, Yvo M. Smulders, Etto C. Eringa
Impact of high dose n-3 polyunsaturated fatty acid treatment on measures of microvascular function and vibration perception in non-alcoholic fatty liver disease: results from the randomised WELCOME trial
Keith G. McCormick, Eleonora Scorletti, Lokpal Bhatia, Philip C. Calder, Michael J. Griffin, Geraldine F. Clough, Christopher D. Byrne
Diabetes with poor glycaemic control does not promote atherosclerosis in genetically modified hypercholesterolaemic minipigs
Rozh H. Al-Mashhadi, Martin M. Bjørklund, Martin B. Mortensen, Christina Christoffersen, Torben Larsen, Erling Falk, Jacob F. Bentzon
Fibroblast growth factor 21 protects the heart from apoptosis in a diabetic mouse model via extracellular signal-regulated kinase 1/2-dependent signalling pathway
Chi Zhang, Zhifeng Huang, Junlian Gu, Xiaoqing Yan, Xuemian Lu, Shanshan Zhou, Shudong Wang, Minglong Shao, Fangfang Zhang, Peng Cheng, Wenke Feng, Yi Tan, Xiaokun Li
Silencing of miR-195 reduces diabetic cardiomyopathy in C57BL/6 mice
Dong Zheng, Jian Ma, Yong Yu, Minghui Li, Rui Ni, Grace Wang, Ruizhen Chen, Jianmin Li, Guo-Chang Fan, James C. Lacefield, Tianqing Peng
Analysis of peri-islet CD45-positive leucocytic infiltrates in long-standing type 1 diabetic patients: additional data regarding cause of death
Shiva Reddy, Nina Zeng, Hussam Al-Diery, Doran Jung, Clifton Yeu, Maximilian O. Joret, Mervyn J. Merrilees, Fiona Wu
Variable effects of statins on glucose homeostasis parameters and their diabetogenic role
Michael S. Kostapanos, Aris P. Agouridis, Moses S. Elisaf
Variable effects of statins on glucose homeostasis parameters and their diabetogenic role. Reply to Kostapanos MS, Agouridis AP and Elisaf MS [letter]
Henna Cederberg, Markku Laakso