Diabetologia

Up front

Advances in drug discovery for human beta cell regeneration

Esra Karakose, Courtney Ackeifi, Peng Wang, Andrew F. Stewart

Systematic review assessing the effectiveness of dietary intervention on gut microbiota in adults with type 2 diabetes

David Houghton, Timothy Hardy, Christopher Stewart, Linda Errington, Christopher P. Day, Michael I. Trenell, Leah Avery

Empagliflozin reduces cardiovascular events, mortality and renal events in participants with type 2 diabetes after coronary artery bypass graft surgery: subanalysis of the EMPA-REG OUTCOME® randomised trial

Subodh Verma, C. David Mazer, David Fitchett, Silvio E. Inzucchi, Egon Pfarr, Jyothis T. George, Bernard Zinman

Reduced risk of heart failure with intensified multifactorial intervention in individuals with type 2 diabetes and microalbuminuria: 21 years of follow-up in the randomised Steno-2 study

Jens Oellgaard, Peter Gæde, Peter Rossing, Rasmus Rørth, Lars Køber, Hans-Henrik Parving, Oluf Pedersen

Nuts as a replacement for carbohydrates in the diabetic diet: a reanalysis of a randomised controlled trial

David J. A. Jenkins, Cyril W. C. Kendall, Benoît Lamarche, Monica S. Banach, Korbua Srichaikul, Edward Vidgen, Sandy Mitchell, Tina Parker, Stephanie Nishi, Balachandran Bashyam, Russell J. de Souza, Christopher Ireland, Sathish C. Pichika, Joseph Beyene, John L. Sievenpiper, Robert G. Josse

Multiplex proteomics for prediction of major cardiovascular events in type 2 diabetes

Christoph Nowak, Axel C. Carlsson, Carl Johan Östgren, Fredrik H. Nyström, Moudud Alam, Tobias Feldreich, Johan Sundström, Juan-Jesus Carrero, Jerzy Leppert, Pär Hedberg, Egil Henriksen, Antonio C. Cordeiro, Vilmantas Giedraitis, Lars Lind, Erik Ingelsson, Tove Fall, Johan Ärnlöv

Genetic variants of gestational diabetes mellitus: a study of 112 SNPs among 8722 women in two independent populations

Ming Ding, Jorge Chavarro, Sjurdur Olsen, Yuan Lin, Sylvia H. Ley, Wei Bao, Shristi Rawal, Louise G. Grunnet, Anne Cathrine B. Thuesen, James L. Mills, Edwina Yeung, Stefanie N. Hinkle, Wei Zhang, Allan Vaag, Aiyi Liu, Frank B. Hu, Cuilin Zhang

An adult-based insulin resistance genetic risk score associates with insulin resistance, metabolic traits and altered fat distribution in Danish children and adolescents who are overweight or obese

Anne-Sofie Graae, Mette Hollensted, Julie T. Kloppenborg, Yuvaraj Mahendran, Theresia M. Schnurr, Emil Vincent R. Appel, Johanne Rask, Tenna R. H. Nielsen, Mia Ø. Johansen, Allan Linneberg, Marit E. Jørgensen, Niels Grarup, Haja N. Kadarmideen, Birgitte Holst, Oluf Pedersen, Jens-Christian Holm, Torben Hansen

Protective role of the ELOVL2/docosahexaenoic acid axis in glucolipotoxicity-induced apoptosis in rodent beta cells and human islets

Lara Bellini, Mélanie Campana, Claude Rouch, Marta Chacinska, Marco Bugliani, Kelly Meneyrol, Isabelle Hainault, Véronique Lenoir, Jessica Denom, Julien Véret, Nadim Kassis, Bernard Thorens, Mark Ibberson, Piero Marchetti, Agnieszka Blachnio-Zabielska, Céline Cruciani-Guglielmacci, Carina Prip-Buus, Christophe Magnan, Hervé Le Stunff

Loss of CXCR3 expression on memory B cells in individuals with long-standing type 1 diabetes

Wendy E. Powell, Stephanie J. Hanna, Claire N. Hocter, Emma Robinson, Joanne Davies, Gareth J. Dunseath, Stephen Luzio, Daniel Farewell, Li Wen, Colin M. Dayan, David A. Price, Kristin Ladell, F. Susan Wong

Vegf-A mRNA transfection as a novel approach to improve mouse and human islet graft revascularisation

Willem Staels, Yannick Verdonck, Yves Heremans, Gunter Leuckx, Sofie De Groef, Carlo Heirman, Eelco de Koning, Conny Gysemans, Kris Thielemans, Luc Baeyens, Harry Heimberg, Nico De Leu

A selective CD28 antagonist and rapamycin synergise to protect against spontaneous autoimmune diabetes in NOD mice

Alix Besançon, Tania Goncalves, Fabrice Valette, Caroline Mary, Bernard Vanhove, Lucienne Chatenoud, Sylvaine You

Exercise training decreases pancreatic fat content and improves beta cell function regardless of baseline glucose tolerance: a randomised controlled trial

Marja A. Heiskanen, Kumail K. Motiani, Andrea Mari, Virva Saunavaara, Jari-Joonas Eskelinen, Kirsi A. Virtanen, Mikko Koivumäki, Eliisa Löyttyniemi, Pirjo Nuutila, Kari K. Kalliokoski, Jarna C. Hannukainen

Effects of acute NEFA manipulation on incretin-induced insulin secretion in participants with and without type 2 diabetes

Brenno Astiarraga, Valéria B. Chueire, Aglécio L. Souza, Ricardo Pereira-Moreira, Sarah Monte Alegre, Andrea Natali, Andrea Tura, Andrea Mari, Ele Ferrannini, Elza Muscelli

The DPP-4 inhibitor vildagliptin impacts the gut microbiota and prevents disruption of intestinal homeostasis induced by a Western diet in mice

Marta Olivares, Audrey M. Neyrinck, Sarah A. Pötgens, Martin Beaumont, Nuria Salazar, Patrice D. Cani, Laure B. Bindels, Nathalie M. Delzenne

Skeletal muscle-specific Cre recombinase expression, controlled by the human α-skeletal actin promoter, improves glucose tolerance in mice fed a high-fat diet

Rami Al Batran, Keshav Gopal, Mackenzie D. Martin, Kim L. Ho, Malak Almutairi, Hanin Aburasayn, Farah Eaton, Jonathan E. Campbell, John R. Ussher

Corneal confocal microscopy for identification of diabetic sensorimotor polyneuropathy: a pooled multinational consortium study

Bruce A. Perkins, Leif E. Lovblom, Vera Bril, Daniel Scarr, Ilia Ostrovski, Andrej Orszag, Katie Edwards, Nicola Pritchard, Anthony Russell, Cirous Dehghani, Danièle Pacaud, Kenneth Romanchuk, Jean K. Mah, Maria Jeziorska, Andrew Marshall, Roni M. Shtein, Rodica Pop-Busui, Stephen I. Lentz, Andrew J. M. Boulton, Mitra Tavakoli, Nathan Efron, Rayaz A. Malik

Folate treatment of pregnant rat dams abolishes metabolic effects in female offspring induced by a paternal pre-conception unhealthy diet

Jian Li, Yong-Ping Lu, Oleg Tsuprykov, Ahmed A. Hasan, Christoph Reichetzeder, Mei Tian, Xiao Li Zhang, Qin Zhang, Guo-Ying Sun, Jingli Guo, Mohamed M. S. Gaballa, Xiao-Ning Peng, Ge Lin, Berthold Hocher

Flash glucose monitoring: objective, not self-referential, outcomes are needed

Roderick E. Warren

Flash glucose monitoring: objective, not self-referential, outcomes are needed. Reply to Warren RE [letter]

Jan Bolinder, Per Oskarsson, Ramiro Antuna, Petronella Geelhoed-Duijvestijn, Jens Krӧger, Raimund Weitgasser

Insights uncovered from experiencing a rise in the incidence of gestational diabetes at a Melbourne hospital

Elisabeth Ng, Madeleine Neff, Shoshana Sztal-Mazer

Insights uncovered from experiencing a rise in the incidence of gestational diabetes at a Melbourne hospital. Reply to Ng E, Neff M, Sztal-Mazer S [letter]

Sarah H. Koning, Jelmer J. van Zanden, Klaas Hoogenberg, Helen L. Lutgers, Alberdina W. Klomp, Fleurisca J. Korteweg, Aren J. van Loon, Bruce H. R. Wolffenbuttel, Paul P. van den Berg

Medicalising pregnancy with new diagnostic criteria for gestational diabetes mellitus: do we need more evidence?

Hema Venkataraman, Ponnusamy Saravanan

Medicalising pregnancy with new diagnostic criteria for gestational diabetes mellitus: do we need more evidence? Reply to Venkataraman H and Saravanan P [letter]

Sarah H. Koning, Jelmer J. van Zanden, Klaas Hoogenberg, Helen L. Lutgers, Alberdina W. Klomp, Fleurisca J. Korteweg, Aren J. van Loon, Bruce H. R. Wolffenbuttel, Paul P. van den Berg