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Malaria Journal

Ausgabe 1/2011

Inhalt (388 Artikel)

Open Access Case report

Variant Plasmodium ovale isolated from a patient infected in Ghana

David Tordrup, Jakob Virenfeldt, Felicie F Andersen, Eskild Petersen

Open Access Research

Detection of an antibody against Plasmodium vivax in residents of Gimpo-si, South Korea, using an indirect fluorescent antibody test

Won-Ja Lee, Hyung-Hwan Kim, Soon-Mi Hwang, Mi-Young Park, Nam-Ryul Kim, Shin-Hyeong Cho, Tae-Sook In, Jung-Yeon Kim, Jetsumon Sattabongkot, Youngjoo Sohn, Hyuck Kim, Jong-Koo Lee, Hyeong-Woo Lee

Open Access Research

Influence of climate and river level on the incidence of malaria in Cacao, French Guiana

Célia Basurko, Matthieu Hanf, René Han-Sze, Stéphanie Rogier, Philippe Héritier, Claire Grenier, Michel Joubert, Mathieu Nacher, Bernard Carme

Open Access Research

Identification of a fibrinogen-related protein (FBN9) gene in neotropical anopheline mosquitoes

Sabrina B Oliveira, Izabela C Ibraim, Wanderli P Tadei, Jeronimo C Ruiz, Laila A Nahum, Cristiana FA Brito, Luciano A Moreira

Open Access Research

First report of the infection of insecticide-resistant malaria vector mosquitoes with an entomopathogenic fungus under field conditions

Annabel FV Howard, Raphael N'Guessan, Constantianus JM Koenraadt, Alex Asidi, Marit Farenhorst, Martin Akogbéto, Bart GJ Knols, Willem Takken

Open Access Opinion

Interferon-γ, a valuable surrogate marker of Plasmodium falciparum pre-erythrocytic stages protective immunity

Blanca-Liliana Perlaza, Jean-Pierre Sauzet, Karima Brahimi, Lbachir BenMohamed, Pierre Druilhe

Open Access Research

Malaria infection by sporozoite challenge induces high functional antibody titres against blood stage antigens after a DNA prime, poxvirus boost vaccination strategy in Rhesus macaques

Muzamil Mahdi Abdel Hamid, Edmond J Remarque, Ibrahim M El Hassan, Ayman A Hussain, David L Narum, Alan W Thomas, Clemens HM Kocken, Walter R Weiss, Bart W Faber

Open Access Research

Why are anopheline mosquitoes not present in the Seychelles?

Vincent Robert, Gérard Rocamora, Simon Julienne, Steven M Goodman

Open Access Research

In vitro susceptibility to quinine and microsatellite variations of the Plasmodium falciparum Na+/H+ exchanger (Pfnhe-1) gene: the absence of association in clinical isolates from the Republic of Congo

Sébastien Briolant, Stéphane Pelleau, Hervé Bogreau, Philippe Hovette, Agnès Zettor, Jacky Castello, Eric Baret, Rémy Amalvict, Christophe Rogier, Bruno Pradines

Open Access Research

Malaria rapid diagnostic kits: quality of packaging, design and labelling of boxes and components and readability and accuracy of information inserts

Philippe Gillet, Jessica Maltha, Veerle Hermans, Raffaella Ravinetto, Cathrien Bruggeman, Jan Jacobs

Open Access Research

Evaluating the effectiveness of IPTi on malaria using routine health information from sentinel health centres in southern Tanzania

Barbara A Willey, Joanna RM Armstrong Schellenberg, Werner Maokola, Kizito Shirima, Mwajuma Chemba, Hassan Mshinda, Pedro Alonso, Marcel Tanner, David Schellenberg

Open Access Research

Seasonal and geographic differences in treatment-seeking and household cost of febrile illness among children in Malawi

Victoria L Ewing, David G Lalloo, Kamija S Phiri, Arantxa Roca-Feltrer, Lindsay J Mangham, Miguel A SanJoaquin

Open Access Research

Induction of strain-transcendent antibodies to placental-type isolates with VAR2CSA DBL3 or DBL5 recombinant proteins

Marion Avril, Megan M Cartwright, Marianne J Hathaway, Joseph D Smith

Open Access Research

Comparative population structure of Plasmodium malariae and Plasmodium falciparum under different transmission settings in Malawi

Marian C Bruce, Allan Macheso, Alex McConnachie, Malcolm E Molyneux

Open Access Research

Immunization with different Pf AMA1 alleles in sequence induces clonal imprint humoral responses that are similar to responses induced by the same alleles as a vaccine cocktail in rabbits

Kwadwo A Kusi, Bart W Faber, Marjolein van der Eijk, Alan W Thomas, Clemens HM Kocken, Edmond J Remarque

Open Access Research

Sequence and gene expression of chloroquine resistance transporter (pfcrt) in the association of in vitro drugs resistance of Plasmodium falciparum

Wanna Chaijaroenkul, Stephen A Ward, Mathirut Mungthin, David Johnson, Andrew Owen, Patrick G Bray, Kesara Na-Bangchang

Open Access Research

Monitoring of clinical efficacy and in vitro sensitivity of Plasmodium vivax to chloroquine in area along Thai Myanmar border during 2009-2010

Poonuch Muhamad, Ronnatrai Ruengweerayut, Wanna Chacharoenkul, Kanchana Rungsihirunrat, Kesara Na-Bangchang

Open Access Research

District level external quality assurance (EQA) of malaria microscopy in Pakistan: pilot implementation and feasibility

Muhammad Amir Khan, John D Walley, Muhammad Arif Munir, Muhammad Aslam Khan, Nayyar Ghias Khokar, Zarfishan Tahir, Athar Nazir, Nazia Shams

Open Access Methodology

A real-time, quantitative PCR method using hydrolysis probes for the monitoring of Plasmodium falciparum load in experimentally infected human volunteers

Rebecca J Rockett, Sarah J Tozer, Chris Peatey, Seweryn Bialasiewicz, David M Whiley, Michael D Nissen, Katharine Trenholme, James S Mc Carthy, Theo P Sloots

Open Access Research

Safety and efficacy of dihydroartemisinin-piperaquine versus artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Zambian children

Michael Nambozi, Jean-Pierre Van Geertruyden, Sebastian Hachizovu, Mike Chaponda, Doreen Mukwamataba, Modest Mulenga, David Ubben, Umberto D'Alessandro

Open Access Research

Pharmacokinetics and pharmacodynamics of artesunate and dihydroartemisinin following oral treatment in pregnant women with asymptomatic Plasmodium falciparum infections in Kinshasa DRC

Marie A Onyamboko, Steven R Meshnick, Lawrence Fleckenstein, Matthew A Koch, Joseph Atibu, Victor Lokomba, Macaya Douoguih, Jennifer Hemingway-Foday, David Wesche, Robert W Ryder, Carl Bose, Linda L Wright, Antoinette K Tshefu, Edmund V Capparelli

Open Access Research

Atorvastatin prevents Plasmodium falciparum cytoadherence and endothelial damage

Zacharie Taoufiq, Paco Pino, Nadine N'dilimabaka, Issam Arrouss, Serge Assi, Florent Soubrier, Angelita Rebollo, Dominique Mazier

Open Access Research

Phase I randomized dose-ascending placebo-controlled trials of ferroquine - a candidate anti-malarial drug - in adults with asymptomatic Plasmodium falciparum infection

Ghyslain Mombo-Ngoma, Christian Supan, Matthias P Dal-Bianco, Michel A Missinou, Pierre-Blaise Matsiegui, Carmen L Ospina Salazar, Saadou Issifou, Daniel Ter-Minassian, Michael Ramharter, Maryvonne Kombila, Peter G Kremsner, Bertrand Lell

Open Access Research

Pv RON2, a new Plasmodium vivax rhoptry neck antigen

Gabriela Arévalo-Pinzón, Hernando Curtidor, Liliana C Patiño, Manuel A Patarroyo

Open Access Research

A phase I trial to evaluate the safety and pharmacokinetics of low-dose methotrexate as an anti-malarial drug in Kenyan adult healthy volunteers

Roma Chilengi, Rashid Juma, Ahmed M Abdallah, Mahfudh Bashraheil, Hudson Lodenyo, Priscilla Nyakundi, Evelyn Anabwani, Amina Salim, Gabriel Mwambingu, Ednah Wenwa, Julie Jemutai, Chemtai Kipkeu, George O Oyoo, Simon N Muchohi, Gilbert Kokwaro, Tim Niehues, Trudie Lang, Alexis Nzila

Open Access Research

Identification of two new protective pre-erythrocytic malaria vaccine antigen candidates

Keith Limbach, Joao Aguiar, Kalpana Gowda, Noelle Patterson, Esteban Abot, Martha Sedegah, John Sacci, Thomas Richie

Open Access Methodology

Rapid diagnostic tests as a source of DNA for Plasmodium species-specific real-time PCR

Lieselotte Cnops, Merel Boderie, Philippe Gillet, Marjan Van Esbroeck, Jan Jacobs

Open Access Research

Are herders protected by their herds? An experimental analysis of zooprophylaxis against the malaria vector Anopheles arabiensis

Iňaki Tirados, Gabriella Gibson, Stephen Young, Stephen J Torr

Open Access Research

Malaria associated symptoms in pregnant women followed-up in Benin

Bich-Tram Huynh, Nadine Fievet, Gildas Gbaguidi, Sophie Borgella, Blaise Guézo Mévo, Achille Massougbodji, Philippe Deloron, Michel Cot

Open Access Research

Plasmodium berghei ANKA infection increases Foxp3, IL-10 and IL-2 in CXCL-10 deficient C57BL/6 mice

Bismark Y Sarfo, Nana O Wilson, Vincent C Bond, Jonathan K Stiles

Open Access Research

Plasmodium Cysteine Repeat Modular Proteins 3 and 4 are essential for malaria parasite transmission from the mosquito to the host

Bruno Douradinha, Kevin D Augustijn, Sally G Moore, Jai Ramesar, Maria M Mota, Andrew P Waters, Chris J Janse, Joanne Thompson

Open Access Methodology

Design, implementation and evaluation of a national campaign to distribute nine million free LLINs to children under five years of age in Tanzania

Kimberly Bonner, Alex Mwita, Peter D McElroy, Susan Omari, Ally Mzava, Christian Lengeler, Naomi Kaspar, Rose Nathan, Joyce Ngegba, Romanus Mtung'e, Nick Brown

Open Access Methodology

Simple flow cytometric detection of haemozoin containing leukocytes and erythrocytes for research on diagnosis, immunology and drug sensitivity testing

Rosangela Frita, Maria Rebelo, Ana Pamplona, Ana M Vigario, Maria M Mota, Martin P Grobusch, Thomas Hänscheid

Open Access Research

Prevalence of molecular markers of anti-malarial drug resistance in Plasmodium vivax and Plasmodium falciparum in two districts of Nepal

Samir Ranjitkar, Mette L Schousboe, Thomas Thyge Thomsen, Madhav Adhikari, Christian MO Kapel, Ib C Bygbjerg, Michael Alifrangis

Open Access Research

Malaria diagnostic testing and treatment practices in three different Plasmodium falciparum transmission settings in Tanzania: before and after a government policy change

Guido JH Bastiaens, Erik Schaftenaar, Arnold Ndaro, Monique Keuter, Teun Bousema, Seif A Shekalaghe

Open Access Research

Genetic variation of TLR-4, TLR-9 and TIRAP genes in Iranian malaria patients

Sedigheh Zakeri, Sakineh Pirahmadi, Akram A Mehrizi, Navid D Djadid

Open Access Research

A longitudinal study on Anopheles mosquito larval abundance in distinct geographical and environmental settings in western Kenya

Susan S Imbahale, Krijn P Paaijmans, Wolfgang R Mukabana, Ron van Lammeren, Andrew K Githeko, Willem Takken

Open Access Review

Reported reasons for not using a mosquito net when one is available: a review of the published literature

Justin Pulford, Manuel W Hetzel, Miranda Bryant, Peter M Siba, Ivo Mueller

Open Access Research

Users' and health service providers' perception on quality of laboratory malaria diagnosis in Tanzania

Yahya A Derua, Deus RS Ishengoma, Rwehumbiza T Rwegoshora, Filemoni Tenu, Julius J Massaga, Leonard EG Mboera, Stephen M Magesa

Open Access Research

Increased proportions of outdoor feeding among residual malaria vector populations following increased use of insecticide-treated nets in rural Tanzania

Tanya L Russell, Nicodem J Govella, Salum Azizi, Christopher J Drakeley, S Patrick Kachur, Gerry F Killeen

Open Access Research

Parasitostatic effect of maslinic acid. I. Growth arrest of Plasmodium falciparum intraerythrocytic stages

Carlos Moneriz, Patricia Marín-García, Andrés García-Granados, José M Bautista, Amalia Diez, Antonio Puyet

Open Access Research

Success of Senegal's first nationwide distribution of long-lasting insecticide-treated nets to children under five - contribution toward universal coverage

Julie I Thwing, Robert T Perry, David A Townes, Mame Birame Diouf, Salif Ndiaye, Moussa Thior

Open Access Methodology

An improved method for undertaking limiting dilution assays for in vitro cloning of Plasmodium falciparum parasites

Alice S Butterworth, Alan J Robertson, Mei-Fong Ho, Michelle L Gatton, James S McCarthy, Katharine R Trenholme

Open Access Research

Plasmodium falciparum msp1, msp2 and glurp allele frequency and diversity in sub-Saharan Africa

Felista Mwingira, Gamba Nkwengulila, Sonja Schoepflin, Deborah Sumari, Hans-Peter Beck, Georges Snounou, Ingrid Felger, Piero Olliaro, Kefas Mugittu

Open Access Research

Icacina senegalensis (Icacinaceae), traditionally used for the treatment of malaria, inhibits in vitro Plasmodium falciparum growth without host cell toxicity

Serigne O Sarr, Sylvie Perrotey, Ibrahima Fall, Saïd Ennahar, Minjie Zhao, Yérim M Diop, Ermanno Candolfi, Eric Marchioni

Open Access Research

Spatio-temporal analysis of malaria incidence at the village level in a malaria-endemic area in Hainan, China

Liang Wen, Chengyi Li, Minghe Lin, Zhengquan Yuan, Donghui Huo, Shenlong Li, Yong Wang, Chenyi Chu, Ruizhong Jia, Hongbin Song

Open Access Research

Spatio-temporal patterns of malaria infection in Bhutan: a country embarking on malaria elimination

Kinley Wangdi, Jaranit Kaewkungwal, Pratap Singhasivanon, Tassanee Silawan, Saranath Lawpoolsri, Nicholas J White

Open Access Methodology

Automated counting for Plasmodium falciparum cytoadherence experiments

Douglas Paton, Brian Faragher, Khairul MF Mustaffa, Tadge Szestak, Steve D Barrett, Alister G Craig

Open Access Research

Malaria risk factors in north-east Tanzania

Peter Winskill, Mark Rowland, George Mtove, Robert C Malima, Matthew J Kirby

Open Access Research

Knowledge and behaviour as determinants of anti-malarial drug use in a peri-urban population from malaria holoendemic region of western Kenya

Carren A Watsierah, Walter GZO Jura, Evans Raballah, Dan Kaseje, Benard Abong'o, Collins Ouma

Open Access Research

The emergence of insecticide resistance in central Mozambique and potential threat to the successful indoor residual spraying malaria control programme

Ana P Abilio, Immo Kleinschmidt, Andrea M Rehman, Nelson Cuamba, Varsha Ramdeen, David S Mthembu, Sarel Coetzer, Rajendra Maharaj, Craig S Wilding, Andrew Steven, Marlize Coleman, Janet Hemingway, Michael Coleman

Open Access Research

Evaluation and pharmacovigilance of projects promoting cultivation and local use of Artemisia annua for malaria

Merlin L Willcox, Shelly Burton, Rosalia Oyweka, Rehema Namyalo, Simon Challand, Keith Lindsey

Open Access Research

Comparison of infant malaria incidence in districts of Maputo province, Mozambique

Orlando P Zacarias, Peter Majlender

Open Access Research

Population pharmacokinetics of artesunate and dihydroartemisinin in pregnant and non-pregnant women with malaria

Carrie A Morris, Marie A Onyamboko, Edmund Capparelli, Matthew A Koch, Joseph Atibu, Vicky Lokomba, Macaya Douoguih, Jennifer Hemingway-Foday, David Wesche, Robert W Ryder, Carl Bose, Linda Wright, Antoinette K Tshefu, Steven Meshnick, Lawrence Fleckenstein

Open Access Research

ABO blood group and the risk of placental malaria in sub-Saharan Africa

Ayola A Adegnika, Adrian JF Luty, Martin P Grobusch, Michael Ramharter, Maria Yazdanbakhsh, Peter G Kremsner, Norbert G Schwarz

Open Access Research

Molecular epidemiology of Plasmodium vivax anti-folate resistance in India

Surendra K Prajapati, Hema Joshi, Vas Dev, Virendra K Dua

Open Access Research

Murine immune responses to a Plasmodium vivax-derived chimeric recombinant protein expressed in Brassica napus

Choonghee Lee, Hyung-Hwan Kim, Kyung Mi Choi, Kyung Won Chung, Yien Kyoung Choi, Mi Jung Jang, Tong-Soo Kim, Nam-Jun Chung, Ho-Gun Rhie, Ho-Sa Lee, Youngjoo Sohn, Hyuck Kim, Sung-Jae Lee, Hyeong-Woo Lee

Open Access Research

Selection of drug resistant mutants from random library of Plasmodium falciparum dihydrofolate reductase in Plasmodium berghei model

Wachiraporn Tipsuwan, Somdet Srichairatanakool, Sumalee Kamchonwongpaisan, Yongyuth Yuthavong, Chairat Uthaipibull

Open Access Research

Antibody levels to multiple malaria vaccine candidate antigens in relation to clinical malaria episodes in children in the Kasena-Nankana district of Northern Ghana

Daniel Dodoo, Frank Atuguba, Samuel Bosomprah, Nana Akosua Ansah, Patrick Ansah, Helena Lamptey, Beverly Egyir, Abraham R Oduro, Ben Gyan, Abraham Hodgson, Kwadwo A Koram

Open Access Research

Low referral completion of rapid diagnostic test-negative patients in community-based treatment of malaria in Sierra Leone

Anna Thomson, Mohammed Khogali, Martin de Smet, Tony Reid, Ahmed Mukhtar, Stefan Peterson, Johan von Schreeb

Open Access Research

Daily Plasmodium yoelii infective mosquito bites do not generate protection or suppress previous immunity against the liver stage

Tzvi Pollock, Ricardo Leitao, Cristina Galan-Rodriguez, Kurt A Wong, Ana Rodriguez

Open Access Research

Which nets are being used: factors associated with mosquito net use in Amhara, Oromia and Southern Nations, Nationalities and Peoples' Regions of Ethiopia

Jeremiah M Ngondi, Patricia M Graves, Teshome Gebre, Aryc W Mosher, Estifanos B Shargie, Paul M Emerson, Frank O Richards Jr

Open Access Research

Parasitostatic effect of maslinic acid. II. Survival increase and immune protection in lethal Plasmodium yoelii-infected mice

Carlos Moneriz, Patricia Marín-García, José M Bautista, Amalia Diez, Antonio Puyet

Open Access Research

Coverage of intermittent prevention treatment with sulphadoxine-pyrimethamine among pregnant women and congenital malaria in Côte d'Ivoire

Henriette A Vanga-Bosson, Patrick A Coffie, Serge Kanhon, Caroline Sloan, Firmin Kouakou, Serge P Eholie, Moussa Kone, François Dabis, Hervé Menan, Didier K Ekouevi

Open Access Research

Reduction of anti-malarial consumption after rapid diagnostic tests implementation in Dar es Salaam: a before-after and cluster randomized controlled study

Valérie D'Acremont, Judith Kahama-Maro, Ndeniria Swai, Deo Mtasiwa, Blaise Genton, Christian Lengeler

Open Access Research

Human saliva as a source of anti-malarial antibodies to examine population exposure to Plasmodium falciparum

Patricia Tabernero Estévez, Judith Satoguina, Davis C Nwakanma, Sheila West, David J Conway, Chris J Drakeley

Open Access Research

In vitro and in vivo assessment of the anti-malarial activity of Caesalpinia pluviosa

Ana Carolina AV Kayano, Stefanie CP Lopes, Fernanda G Bueno, Elaine C Cabral, Wanessa C Souza-Neiras, Lucy M Yamauchi, Mary A Foglio, Marcos N Eberlin, João Carlos P Mello, Fabio TM Costa

Open Access Case report

Chloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand

Marcus J Rijken, Machteld E Boel, Bruce Russell, Mallika Imwong, Mara L Leimanis, Aung Pyae Phyo, Atis Muehlenbachs, Niklas Lindegardh, Rose McGready, Laurent Rénia, Georges Snounou, Pratap Singhasivanon, François Nosten

Open Access Methodology

Comparison of commercial kits to measure cytokine responses to Plasmodium falciparum by multiplex microsphere suspension array technology

Tamara K Berthoud, Maria Nelia Manaca, Diana Quelhas, Ruth Aguilar, Caterina Guinovart, Laura Puyol, Arnoldo Barbosa, Pedro L Alonso, Carlota Dobaño

Open Access Methodology

Quantum dots: a new tool for anti-malarial drug assays

Min-Je Ku, Fernando M Dossin, Youngseon Choi, Carolina B Moraes, Jiyoung Ryu, Rita Song, Lucio H Freitas-Junior

Open Access Research

High prevalence of dhfr triple mutant and correlation with high rates of sulphadoxine-pyrimethamine treatment failures in vivo in Gabonese children

Ghyslain Mombo-Ngoma, Sunny Oyakhirome, Rosalynn Ord, Julian J Gabor, Katja C Greutélaers, Katharina Profanter, Benedikt Greutélaers, Florian Kurth, Bertrand Lell, Jürgen FJ Kun, Saadou Issifou, Cally Roper, Peter G Kremsner, Martin P Grobusch

Open Access Methodology

Mapping hypoendemic, seasonal malaria in rural Bandarban, Bangladesh: a prospective surveillance

Wasif A Khan, David A Sack, Sabeena Ahmed, Chai Shawi Prue, Mohammad Shafiul Alam, Rashidul Haque, Jacob Khyang, Malathi Ram, Jasmin Akter, Myaing Myaing Nyunt, Douglas Norris, Gregory Glass, Timothy Shields, Md Zahirul Haq, Alejandro Cravioto, David J Sullivan Jr

Open Access Research

Population genetic analysis of the Plasmodium falciparum 6-cys protein Pf38 in Papua New Guinea reveals domain-specific balancing selection

John C Reeder, Johanna Wapling, Ivo Mueller, Peter M Siba, Alyssa E Barry

Open Access Case report

Marked increase in etravirine and saquinavir plasma concentrations during atovaquone/proguanil prophylaxis

Chiara Tommasi, Rita Bellagamba, Massimo Tempestilli, Antonio D'Avolio, Anna L Gallo, Jelena Ivanovic, Emanuele Nicastri, Leopoldo P Pucillo, Pasquale Narciso

Open Access Research

The clinical burden of malaria in Nairobi: a historical review and contemporary audit

Sandra A Mudhune, Emelda A Okiro, Abdisalan M Noor, Dejan Zurovac, Elizabeth Juma, Sam A Ochola, Robert W Snow

Open Access Research

Self-reported fever, treatment actions and malaria infection prevalence in the northern states of Sudan

Khalid A Elmardi, Abdisalan M Noor, Sophie Githinji, Tareg M Abdelgadir, ElFatih M Malik, Robert W Snow

Open Access Research

Respondent-driven sampling on the Thailand-Cambodia border. II. Knowledge, perception, practice and treatment-seeking behaviour of migrants in malaria endemic zones

Piyaporn Wangroongsarb, Wichai Satimai, Amnat Khamsiriwatchara, Julie Thwing, James M Eliades, Jaranit Kaewkungwal, Charles Delacollette

Open Access Research

Respondent-driven sampling on the Thailand-Cambodia border. I. Can malaria cases be contained in mobile migrant workers?

Amnat Khamsiriwatchara, Piyaporn Wangroongsarb, Julie Thwing, James Eliades, Wichai Satimai, Charles Delacollette, Jaranit Kaewkungwal

Open Access Research

Status of pesticide management in the practice of vector control: a global survey in countries at risk of malaria or other major vector-borne diseases

Henk van den Berg, Jeffrey Hii, Agnes Soares, Abraham Mnzava, Birkinesh Ameneshewa, Aditya P Dash, Mikhail Ejov, Soo Hian Tan, Graham Matthews, Rajpal S Yadav, Morteza Zaim

Open Access Research

Anti-malarial effect of gum arabic

Adil Ballal, Diwakar Bobbala, Syed M Qadri, Michael Föller, Daniela Kempe, Omaima Nasir, Amal Saeed, Florian Lang

Open Access Case study

Innovative public-private partnerships to maximize the delivery of anti-malarial medicines: lessons learned from the ASAQ Winthrop experience

François Bompart, Jean-René Kiechel, Robert Sebbag, Bernard Pecoul

Open Access Editorial

Travellers' malaria - 'one shoe does not fit all'

Patricia Schlagenhauf, Marcel Hommel

Open Access Research

Patterns of anti-malarial drug treatment among pregnant women in Uganda

Laura R Sangaré, Noel S Weiss, Paula E Brentlinger, Barbra A Richardson, Sarah G Staedke, Mpungu S Kiwuwa, Andy Stergachis

Open Access Research

Anopheles gambiae distribution and insecticide resistance in the cities of Douala and Yaoundé (Cameroon): influence of urban agriculture and pollution

Christophe Antonio-Nkondjio, Billy Tene Fossog, Cyrille Ndo, Benjamin Menze Djantio, Serge Zebaze Togouet, Parfait Awono-Ambene, Carlo Costantini, Charles S Wondji, Hilary Ranson

Open Access Research

Alternative splicing of the Anopheles gambiae Dscam gene in diverse Plasmodium falciparum infections

Paul H Smith, Jonathan M Mwangi, Yaw A Afrane, Guiyun Yan, Darren J Obbard, Lisa C Ranford-Cartwright, Tom J Little

Open Access Research

Trends in malaria research in 11 Asian Pacific countries: an analysis of peer-reviewed publications over two decades

Finn Andersen, Nick M Douglas, Dorina Bustos, Gawrie Galappaththy, Gao Qi, Michelle S Hsiang, Rita Kusriastuti, Kamini Mendis, George Taleo, Maxine Whittaker, Ric N Price, Lorenz von Seidlein

Open Access Research

Plasmodium falciparum transmission and aridity: a Kenyan experience from the dry lands of Baringo and its implications for Anopheles arabiensis control

Albert O Mala, Lucy W Irungu, Josephat I Shililu, Ephantus J Muturi, Charles M Mbogo, Joseph K Njagi, Wolfgang R Mukabana, John I Githure

Open Access Research

Unexpectedly long incubation period of Plasmodium vivax malaria, in the absence of chemoprophylaxis, in patients diagnosed outside the transmission area in Brazil

Patrícia Brasil, Anielle de Pina Costa, Renata Saraiva Pedro, Clarisse da Silveira Bressan, Sidnei da Silva, Pedro Luiz Tauil, Cláudio Tadeu Daniel-Ribeiro

Open Access Research

Heterogeneous decrease in malaria prevalence in children over a six-year period in south-western Uganda

Pierre De Beaudrap, Carolyn Nabasumba, Francesco Grandesso, Eleanor Turyakira, Birgit Schramm, Yap Boum II, Jean-François Etard

Open Access Research

Prevalence and risk factors of malaria among children in southern highland Rwanda

Jean-Bosco Gahutu, Christian Steininger, Cyprien Shyirambere, Irene Zeile, Neniling Cwinya-Ay, Ina Danquah, Christoph H Larsen, Teunis A Eggelte, Aline Uwimana, Corine Karema, Andre Musemakweri, Gundel Harms, Frank P Mockenhaupt

Open Access Research

Laboratory selection for an accelerated mosquito sexual development rate

Clelia F Oliva, Mark Q Benedict, Guy Lempérière, Jérémie Gilles

Open Access Review

Quinine, an old anti-malarial drug in a modern world: role in the treatment of malaria

Jane Achan, Ambrose O Talisuna, Annette Erhart, Adoke Yeka, James K Tibenderana, Frederick N Baliraine, Philip J Rosenthal, Umberto D'Alessandro

Open Access Research

Community perceptions of malaria and vaccines in the South Coast and Busia regions of Kenya

David I Ojakaa, Peter Ofware, Yvonne W Machira, Emmanuel Yamo, Yvette Collymore, Antoinette Ba-Nguz, Preeti Vansadia, Allison Bingham

Open Access Research

Treatment of uncomplicated malaria at public health facilities and medicine retailers in south-eastern Nigeria

Lindsay J Mangham, Bonnie Cundill, Ogochukwu Ezeoke, Emmanuel Nwala, Benjamin SC Uzochukwu, Virginia Wiseman, Obinna Onwujekwe

Open Access Research

Community case management of malaria using ACT and RDT in two districts in Zambia: achieving high adherence to test results using community health workers

Pascalina Chanda, Busiku Hamainza, Hawela B Moonga, Victor Chalwe, Franco Pagnoni

Open Access Research

Relative costs and effectiveness of treating uncomplicated malaria in two rural districts in Zambia: implications for nationwide scale-up of home-based management

Pascalina Chanda, Busiku Hamainza, Hawela B Moonga, Victor Chalwe, Patrick Banda, Franco Pagnoni

Open Access Research

Bionomics of the malaria vector Anopheles farauti in Temotu Province, Solomon Islands: issues for malaria elimination

Hugo Bugoro, Robert D Cooper, Charles Butafa, Charles Iro'ofa, Donna O Mackenzie, Cheng-Chen Chen, Tanya L Russell

Open Access Research

Spatial variation and socio-economic determinants of Plasmodium falciparum infection in northeastern Tanzania

Bruno P Mmbando, Mathias L Kamugisha, John P Lusingu, Filbert Francis, Deus S Ishengoma, Thor G Theander, Martha M Lemnge, Thomas H Scheike

Open Access Research

The contribution of aestivating mosquitoes to the persistence of Anopheles gambiae in the Sahel

Abdoulaye Adamou, Adama Dao, Seydou Timbine, Yaya Kassogué, Alpha Seydou Yaro, Moussa Diallo, Sékou F Traoré, Diana L Huestis, Tovi Lehmann

Open Access Research

Use of remote sensing to identify spatial risk factors for malaria in a region of declining transmission: a cross-sectional and longitudinal community survey

William J Moss, Harry Hamapumbu, Tamaki Kobayashi, Timothy Shields, Aniset Kamanga, Julie Clennon, Sungano Mharakurwa, Philip E Thuma, Gregory Glass

Open Access Research

Cost risk benefit analysis to support chemoprophylaxis policy for travellers to malaria endemic countries

Eduardo Massad, Ben C Behrens, Francisco AB Coutinho, Ronald H Behrens

Open Access Commentary

"Test and treat" or presumptive treatment for malaria in high transmission situations? A reflection on the latest WHO guidelines

Bertrand Graz, Merlin Willcox, Thomas Szeless, André Rougemont

Open Access Research

Paracetamol versus placebo in treatment of non-severe malaria in children in Guinea-Bissau: a randomized controlled trial

Poul-Erik Kofoed, Johan Ursing, Amabelia Rodrigues, Lars Rombo

Open Access Research

Polymorphism of Plasmodium falciparum Na+/H+ exchanger is indicative of a low in vitro quinine susceptibility in isolates from Viet Nam

Véronique Sinou, Le Hong Quang, Stéphane Pelleau, Vu Nhu Huong, Nguyen Thu Huong, Le Minh Tai, Lionel Bertaux, Marc Desbordes, Christine Latour, Lai Quang Long, Nguyen Xuan Thanh, Daniel Parzy

Open Access Methodology

Malaria chemoprophylaxis recommendations for immigrants to Europe, visiting relatives and friends - a Delphi method study

Guido Calleri, Ron H Behrens, Matthias L Schmid, Federico Gobbi, Martin P Grobusch, Francesco Castelli, Joaquim Gascon, Zeno Bisoffi, Tomas Jelinek, Pietro Caramello

Open Access Research

The combined effect of determinants on coverage of intermittent preventive treatment of malaria during pregnancy in the Kilombero Valley, Tanzania

Karin Gross, Sandra Alba, Joanna Schellenberg, Flora Kessy, Iddy Mayumana, Brigit Obrist

Open Access Research

The initial pharmaceutical development of an artesunate/amodiaquine oral formulation for the treatment of malaria: a public-private partnership

Catherine Lacaze, Tina Kauss, Jean-René Kiechel, Antonella Caminiti, Fawaz Fawaz, Laurent Terrassin, Sylvie Cuart, Luc Grislain, Visweswaran Navaratnam, Bellabes Ghezzoul, Karen Gaudin, Nick J White, Piero L Olliaro, Pascal Millet

Open Access Research

Central nervous system exposure of next generation quinoline methanols is reduced relative to mefloquine after intravenous dosing in mice

Geoffrey S Dow, Erin Milner, Ian Bathurst, Jayendra Bhonsle, Diana Caridha, Sean Gardner, Lucia Gerena, Michael Kozar, Charlotte Lanteri, Anne Mannila, William McCalmont, Jay Moon, Kevin D Read, Suzanne Norval, Norma Roncal, David M Shackleford, Jason Sousa, Jessica Steuten, Karen L White, Qiang Zeng, Susan A Charman

Open Access Research

Urban malaria and associated risk factors in Jimma town, south-west Ethiopia

Abebe Alemu, Wondewosen Tsegaye, Lemu Golassa, Gemeda Abebe

Open Access Research

Malaria in Kakuma refugee camp, Turkana, Kenya: facilitation of Anopheles arabiensis vector populations by installed water distribution and catchment systems

M Nabie Bayoh, Willis Akhwale, Maurice Ombok, David Sang, Sammy C Engoki, Dan Koros, Edward D Walker, Holly A Williams, Heather Burke, Gregory L Armstrong, Martin S Cetron, Michelle Weinberg, Robert Breiman, Mary J Hamel

Open Access Research

Reduced cardiac output in imported Plasmodium falciparum malaria

Johanna Herr, Parisa Mehrfar, Stefan Schmiedel, Dominic Wichmann, Norbert W Brattig, Gerd D Burchard, Jakob P Cramer

Open Access Research

Hypericum lanceolatum (Hypericaceae) as a potential source of new anti-malarial agents: a bioassay-guided fractionation of the stem bark

Denis Zofou, Théodora K Kowa, Hippolyte K Wabo, Moses N Ngemenya, Pierre Tane, Vincent PK Titanji

Open Access Research

Measuring naturally acquired immune responses to candidate malaria vaccine antigens in Ghanaian adults

Daniel Dodoo, Michael R Hollingdale, Dorothy Anum, Kwadwo A Koram, Ben Gyan, Bartholomew D Akanmori, Josephine Ocran, Susan Adu-Amankwah, Harini Geneshan, Esteban Abot, Jennylyn Legano, Glenna Banania, Renato Sayo, Donald Brambilla, Sanjai Kumar, Denise L Doolan, William O Rogers, Judith Epstein, Thomas L Richie, Martha Sedegah

Open Access Research

Clinical trial of extended-dose chloroquine for treatment of resistant falciparum malaria among Afghan refugees in Pakistan

Natasha Howard, Naeem Durrani, Sanda Sanda, Khalid Beshir, Rachel Hallett, Mark Rowland

Open Access Research

Evaluation of allelic forms of the erythrocyte binding antigen 175 (EBA-175) in Plasmodium falciparum field isolates from Brazilian endemic area

Daiana S Perce-da-Silva, Dalma M Banic, Josué C Lima-Junior, Fátima Santos, Cláudio T Daniel-Ribeiro, Joseli de Oliveira-Ferreira, Lilian R Pratt-Riccio

Open Access Research

Spatial patterns of malaria in a land reform colonization project, Juruena municipality, Mato Grosso, Brazil

Elaine Cristina de Oliveira, Emerson Soares dos Santos, Peter Zeilhofer, Reinaldo Souza-Santos, Marina Atanaka-Santos

Open Access Review

Plasmodial sugar transporters as anti-malarial drug targets and comparisons with other protozoa

Ksenija Slavic, Sanjeev Krishna, Elvira T Derbyshire, Henry M Staines

Open Access Research

Malaria prevalence pattern observed in the highland fringe of Butajira, Southern Ethiopia: A longitudinal study from parasitological and entomological survey

Solomon Tesfaye, Yeshambel Belyhun, Takele Teklu, Tesfaye Mengesha, Beyene Petros

Open Access Research

Validation of oral fluid samples to monitor serological changes to Plasmodium falciparum: An observational study in southern Zambia

Alexis P Chidi, Sandra Chishimba, Tamaki Kobayashi, Harry Hamapumbu, Sungano Mharakurwa, Philip E Thuma, William J Moss

Open Access Research

Prozone in malaria rapid diagnostics tests: how many cases are missed?

Philippe Gillet, Annelies Scheirlinck, Jocelijn Stokx, Anja De Weggheleire, Hélder S Chaúque, Oreana DJV Canhanga, Benvindo T Tadeu, Carla DD Mosse, Armindo Tiago, Samuel Mabunda, Cathrien Bruggeman, Emmanuel Bottieau, Jan Jacobs

Open Access Research

Field trial of three different Plasmodium vivax- detecting rapid diagnostic tests with and without evaporative cool box storage in Afghanistan

Amy FW Mikhail, Toby J Leslie, Mohammad I Mayan, Rohullah Zekria, Nader Mohammad, Mohammad A Hasanzai, Najibullah Safi, Christopher JM Whitty, Mark Rowland

Open Access Research

Efficacy of PermaNet® 2.0 and PermaNet® 3.0 against insecticide-resistant Anopheles gambiae in experimental huts in Côte d'Ivoire

Benjamin G Koudou, Alphonsine A Koffi, David Malone, Janet Hemingway

Open Access Case report

Gestational malaria associated to Plasmodium vivax and Plasmodium falciparum placental mixed-infection followed by foetal loss: a case report from an unstable transmission area in Brazil

Bruna O Carvalho, Joycenéa S Matsuda, Sergio LB Luz, Flor E Martinez-Espinosa, Juliana A Leite, Fernanda Franzin, Patrícia P Orlandi, Gustavo B Gregoracci, Marcus VG Lacerda, Paulo A Nogueira, Fabio TM Costa

Open Access Research

Safety and immunogenicity of multi-antigen AMA1-based vaccines formulated with CoVaccine HT™ and Montanide ISA 51 in rhesus macaques

Kwadwo A Kusi, Edmond J Remarque, Vanessa Riasat, Vanessa Walraven, Alan W Thomas, Bart W Faber, Clemens HM Kocken

Open Access Research

Real-time PCR assay and rapid diagnostic tests for the diagnosis of clinically suspected malaria patients in Bangladesh

Mohammad Shafiul Alam, Abu Naser Mohon, Shariar Mustafa, Wasif Ali Khan, Nazrul Islam, Mohammad Jahirul Karim, Hamida Khanum, David J Sullivan Jr, Rashidul Haque

Open Access Research

Accuracy of malaria rapid diagnostic tests in community studies and their impact on treatment of malaria in an area with declining malaria burden in north-eastern Tanzania

Deus S Ishengoma, Filbert Francis, Bruno P Mmbando, John PA Lusingu, Pamela Magistrado, Michael Alifrangis, Thor G Theander, Ib C Bygbjerg, Martha M Lemnge

Open Access Research

Population, behavioural and environmental drivers of malaria prevalence in the Democratic Republic of Congo

Jane P Messina, Steve M Taylor, Steven R Meshnick, Andrew M Linke, Antoinette K Tshefu, Benjamin Atua, Kashamuka Mwandagalirwa, Michael Emch

Open Access Research

Relationship between care-givers' misconceptions and non-use of ITNs by under-five Nigerian children

Ekundayo D Arogundade, Samson B Adebayo, Jennifer Anyanti, Ernest Nwokolo, Olaronke Ladipo, Augustine Ankomah, Martin M Meremikwu

Open Access Research

Population dynamics, structure and behavior of Anopheles darlingi in a rural settlement in the Amazon rainforest of Acre, Brazil

Paulo Rufalco Moutinho, Luis Herman Soares Gil, Rafael Bastos Cruz, Paulo Eduardo Martins Ribolla

Open Access Research

Determinants of bed net use in children under five and household bed net ownership on Bioko Island, Equatorial Guinea

Alberto L García-Basteiro, Christopher Schwabe, Cynthia Aragon, Giovanna Baltazar, Andrea M Rehman, Abrahan Matias, Gloria Nseng, Immo Kleinschmidt

Open Access Research

Outdoor host seeking behaviour of Anopheles gambiae mosquitoes following initiation of malaria vector control on Bioko Island, Equatorial Guinea

Michael R Reddy, Hans J Overgaard, Simon Abaga, Vamsi P Reddy, Adalgisa Caccone, Anthony E Kiszewski, Michel A Slotman

Open Access Research

Comparative study of the efficacy and tolerability of dihydroartemisinin - piperaquine - trimethoprim versus artemether - lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Cameroon, Ivory Coast and Senegal

Hervé Menan, Oumar Faye, Albert Same-Ekobo, Agbaya Serge S Oga, Babacar Faye, Christiane P Kiki Barro, Thomas Kuete, Jean-Louis N'diaye, Ama-Moor Vicky, Rogert Tine, William Yavo, Dieynaba Kane, Kondo F Kassi, Moussa Kone

Open Access Research

Plasmodium falciparum isolates from southern Ghana exhibit polymorphisms in the SERCA-type PfATPase6 though sensitive to artesunate in vitro

Bethel Kwansa-Bentum, Irene Ayi, Takashi Suzuki, Joseph Otchere, Takashi Kumagai, William K Anyan, Joseph HN Osei, Hiroko Asahi, Michael F Ofori, Nobuaki Akao, Michael D Wilson, Daniel A Boakye, Nobuo Ohta

Open Access Methodology

Plasmodium vivax: comparison of immunogenicity among proteins expressed in the cell-free systems of Escherichia coli and wheat germ by suspension array assays

Edmilson Rui, Carmen Fernandez-Becerra, Satoru Takeo, Sergi Sanz, Marcus VG Lacerda, Takafumi Tsuboi, Hernando A del Portillo

Open Access Research

Investigating preferences for mosquito-control technologies in Mozambique with latent class analysis

Rachel A Smith, Victoria C Barclay, Jill L Findeis

Open Access Methodology

Optimal designs for population pharmacokinetic studies of oral artesunate in patients with uncomplicated falciparum malaria

Kris M Jamsen, Stephen B Duffull, Joel Tarning, Niklas Lindegardh, Nicholas J White, Julie A Simpson

Open Access Research

Climate forcing and desert malaria: the effect of irrigation

Andres Baeza, Menno J Bouma, Andy P Dobson, Ramesh Dhiman, Harish C Srivastava, Mercedes Pascual

Open Access Methodology

Specific, sensitive and rapid detection of human plasmodium knowlesi infection by loop-mediated isothermal amplification (LAMP) in blood samples

Yee-Ling Lau, Mun-Yik Fong, Rohela Mahmud, Phooi-Yee Chang, Vanitha Palaeya, Fei-Wen Cheong, Lit-Chein Chin, Claudia N Anthony, Abdulsalam M Al-Mekhlafi, Yeng Chen

Open Access Research

An exploratory study of treated-bed nets in Timor-Leste: patterns of intended and alternative usage

Andrew A Lover, Brett A Sutton, Angelina J Asy, Annelies Wilder-Smith

Open Access Research

Evaluating RNAlater® as a preservative for using near-infrared spectroscopy to predict Anopheles gambiae age and species

Maggy Sikulu, Kayla M Dowell, Leon E Hugo, Robert A Wirtz, Kristin Michel, Kamaranga HS Peiris, Sarah Moore, Gerry F Killeen, Floyd E Dowell

Open Access Research

Is the current decline in malaria burden in sub-Saharan Africa due to a decrease in vector population?

Dan W Meyrowitsch, Erling M Pedersen, Michael Alifrangis, Thomas H Scheike, Mwelecele N Malecela, Stephen M Magesa, Yahya A Derua, Rwehumbiza T Rwegoshora, Edwin Michael, Paul E Simonsen

Open Access Research

Spatial and temporal patterns of malaria incidence in Mozambique

Orlando P Zacarias, Mikael Andersson

Open Access Methodology

Modelling malaria elimination on the internet

Richard J Maude, Sompob Saralamba, Adrian Lewis, Dean Sherwood, Nicholas J White, Nicholas PJ Day, Arjen M Dondorp, Lisa J White

Open Access Methodology

Assessment of LED fluorescence microscopy for the diagnosis of Plasmodium falciparum infections in Gabon

Dominic Lenz, Peter G Kremsner, Bertrand Lell, Barbara Biallas, Michael Boettcher, Benjamin Mordmüller, Ayola A Adegnika

Open Access Research

False positive circumsporozoite protein ELISA: a challenge for the estimation of the entomological inoculation rate of malaria and for vector incrimination

Lies Durnez, Wim Van Bortel, Leen Denis, Patricia Roelants, Aurélie Veracx, Ho Dinh Trung, Tho Sochantha, Marc Coosemans

Open Access Review

Mathematical models of malaria - a review

Sandip Mandal, Ram Rup Sarkar, Somdatta Sinha

Open Access Research

Changing patterns of malaria during 1996-2010 in an area of moderate transmission in Southern Senegal

Philippe Brasseur, Malick Badiane, Moustafa Cisse, Patrice Agnamey, Michel T Vaillant, Piero L Olliaro

Open Access Research

Community participation for malaria elimination in tafea province, vanuatu: part ii. social and cultural aspects of treatment-seeking behaviour

Anna Tynan, Jo-An Atkinson, Hilson Toaliu, George Taleo, Lisa Fitzgerald, Maxine Whittaker, Ian Riley, Mark Schubert, Andrew Vallely

Open Access Research

Wide cross-reactivity between Anopheles gambiae and Anopheles funestus SG6 salivary proteins supports exploitation of gSG6 as a marker of human exposure to major malaria vectors in tropical Africa

Cinzia Rizzo, Raffaele Ronca, Gabriella Fiorentino, Valentina D Mangano, Sodiomon B Sirima, Issa Nèbiè, Vincenzo Petrarca, David Modiano, Bruno Arcà

Open Access Research

Community screening and treatment of asymptomatic carriers of Plasmodium falciparum with artemether-lumefantrine to reduce malaria disease burden: a modelling and simulation analysis

Steven E Kern, Alfred B Tiono, Michael Makanga, Adama Dodji Gbadoé, Zulfiqarali Premji, Oumar Gaye, Issaka Sagara, David Ubben, Marc Cousin, Fiyinfolu Oladiran, Oliver Sander, Bernhards Ogutu

Open Access Research

Radical curative efficacy of tafenoquine combination regimens in Plasmodium cynomolgi-infected Rhesus monkeys (Macaca mulatta)

Geoffrey S Dow, Montip Gettayacamin, Pranee Hansukjariya, Rawiwan Imerbsin, Srawuth Komcharoen, Jetsumon Sattabongkot, Dennis Kyle, Wilbur Milhous, Simon Cozens, David Kenworthy, Anne Miller, Jim Veazey, Colin Ohrt

Open Access Research

Detection of high levels of mutations involved in anti-malarial drug resistance in Plasmodium falciparum and Plasmodium vivax at a rural hospital in southern Ethiopia

Patricia Mula, Amalia Fernández-Martínez, Aida de Lucio, Jose Manuel Ramos, Francisco Reyes, Vicenta González, Agustín Benito, Pedro Berzosa

Open Access Research

Reduction in host-finding behaviour in fungus-infected mosquitoes is correlated with reduction in olfactory receptor neuron responsiveness

Justin George, Simon Blanford, Michael J Domingue, Matthew B Thomas, Andrew F Read, Thomas C Baker

Open Access Opinion

Designing a sustainable strategy for malaria control?

Clive Shiff, Phil Thuma, David Sullivan, Sungano Mharakurwa

Open Access Research

Preventing malaria in pregnancy through community-directed interventions: evidence from Akwa Ibom State, Nigeria

Joseph C Okeibunor, Bright C Orji, William Brieger, Gbenga Ishola, Emmanuel 'Dipo Otolorin, Barbara Rawlins, Enobong U Ndekhedehe, Nkechi Onyeneho, Günther Fink

Open Access Research

Exposure to anti-malarial drugs and monitoring of adverse drug reactions using toll-free mobile phone calls in private retail sector in Sagamu, Nigeria: implications for pharmacovigilance

Ahmed A Adedeji, Bilqees Sanusi, Azeez Tella, Motunrayo Akinsanya, Olubusola Ojo, Mufliat O Akinwunmi, Olubukola A Tikare, Isiaka A Ogunwande, Omobola A Ogundahunsi, Olajide O Ayilara, Taofeeqah T Ademola, Fatai A Fehintola, Olumide AT Ogundahunsi

Open Access Methodology

Opportunities for improving pLDH-based malaria diagnostic tests

Robert C Piper, Ian Buchanan, Young Ho Choi, Michael T Makler

Open Access Review

Taking stock: provider prescribing practices in the presence and absence of ACT stock

Bernadette Hensen, Lucy Smith Paintain, Rima Shretta, Jane Bruce, Caroline Jones, Jayne Webster

Open Access Research

Plasmodium falciparum glutamate dehydrogenase a is dispensable and not a drug target during erythrocytic development

Janet Storm, Jan Perner, Isabela Aparicio, Eva-Maria Patzewitz, Kellen Olszewski, Manuel Llinas, Paul C Engel, Sylke Müller

Open Access Research

In vivo efficacy of artemether-lumefantrine against uncomplicated Plasmodium falciparum malaria in Central Ethiopia

Jimee Hwang, Bereket H Alemayehu, David Hoos, Zenebe Melaku, Samuel G Tekleyohannes, Takele Teshi, Sintayehu G Birhanu, Leykun Demeke, Kedir Gobena, Moges Kassa, Daddi Jima, Richard Reithinger, Henry Nettey, Michael Green, Joseph L Malone, S Patrick Kachur, Scott Filler

Open Access Research

Comparison of the antibody responses to Plasmodium vivax and Plasmodium falciparum antigens in residents of Mandalay, Myanmar

Tong-Soo Kim, Hyung-Hwan Kim, Jung-Yeon Kim, Yoon Kong, Byoung-Kuk Na, Khin Lin, Sung-Ung Moon, Yeon-Joo Kim, Myoung-Hee Kwon, Youngjoo Sohn, Hyuck Kim, Hyeong-Woo Lee

Open Access Research

Molecular markers of resistance to sulphadoxine-pyrimethamine during intermittent preventive treatment of pregnant women in Benin

Gwladys Bertin, Valérie Briand, Diana Bonaventure, Ambre Carrieu, Achille Massougbodji, Michel Cot, Philippe Deloron

Open Access Research

Multicentric assessment of the efficacy and tolerability of dihydroartemisinin-piperaquine compared to artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in sub-Saharan Africa

William Yavo, Babacar Faye, Thomas Kuete, Vincent Djohan, Serge A Oga, Richard R Kassi, Mariama Diatta, Moor V Ama, Roger Tine, Jean-Louis Ndiaye, Jean-Bedel Evi, Albert Same-Ekobo, Oumar Faye, Moussa Koné

Open Access Research

Target product profile choices for intra-domiciliary malaria vector control pesticide products: repel or kill?

Gerry F Killeen, Nakul Chitnis, Sarah J Moore, Fredros O Okumu

Open Access Research

Laboratory prediction of the requirement for renal replacement in acute falciparum malaria

Josh Hanson, Md Mahtab Uddin Hasan, Annick A Royakkers, Shamsul Alam, Prakaykaew Charunwatthana, Richard J Maude, Sam T Douthwaite, Emran Bin Yunus, Murty L Mantha, Marcus J Schultz, M Abul Faiz, Nicholas J White, Nicholas P Day, Arjen M Dondorp

Open Access Methodology

Design of a phase III multicenter trial to evaluate the efficacy of the RTS,S/AS01 malaria vaccine in children across diverse transmission settings in Africa

Amanda Leach, Johan Vekemans, Marc Lievens, Opokua Ofori-Anyinam, Conor Cahill, Seth Owusu-Agyei, Salim Abdulla, Eusebio Macete, Patricia Njuguna, Barbara Savarese, Christian Loucq, W Ripley Ballou

Open Access Research

Strict adherence to malaria rapid test results might lead to a neglect of other dangerous diseases: a cost benefit analysis from Burkina Faso

Zeno Bisoffi, Sodiomon B Sirima, Filip Meheus, Claudia Lodesani, Federico Gobbi, Andrea Angheben, Halidou Tinto, Bouma Neya, Klara Van den Ende, Annalisa Romeo, Jef Van den Ende

Open Access Research

Malaria epidemiology in the Ahafo area of Ghana

Kwaku P Asante, Charles Zandoh, Dominic B Dery, Charles Brown, George Adjei, Yaw Antwi-Dadzie, Martin Adjuik, Kofi Tchum, David Dosoo, Seeba Amenga-Etego, Christine Mensah, Kwabena B Owusu-Sekyere, Chris Anderson, Gary Krieger, Seth Owusu-Agyei

Open Access Research

Comparative analyses reveal discrepancies among results of commonly used methods for Anopheles gambiae molecular form identification

Federica Santolamazza, Beniamino Caputo, Maria Calzetta, José L Vicente, Emiliano Mancini, Vincenzo Petrarca, João Pinto, Alessandra della Torre

Open Access Methodology

Statistical methodology for the evaluation of vaccine efficacy in a phase III multi-centre trial of the RTS,S/AS01 malaria vaccine in African children

Marc Lievens, John J Aponte, John Williamson, Bruno Mmbando, Ali Mohamed, Philip Bejon, Amanda Leach

Open Access Methodology

High-speed shaking of frozen blood clots for extraction of human and malaria parasite DNA

Klara Lundblom, Alex Macharia, Marianne Lebbad, Adan Mohammed, Anna Färnert

Open Access Research

Randomized trials of artemisinin-piperaquine, dihydroartemisinin-piperaquine phosphate and artemether-lumefantrine for the treatment of multi-drug resistant falciparum malaria in Cambodia-Thailand border area

Jianping Song, Duong Socheat, Bo Tan, Suon Seila, Ying Xu, Fengzhen Ou, Sreng Sokunthea, Leap Sophorn, Chongjun Zhou, Changsheng Deng, Qi Wang, Guoqiao Li

Open Access Research

Screening for adulticidal bioactivity of South African plants against Anopheles arabiensis

Rajendra Maharaj, Vinesh Maharaj, Neil R Crouch, Niresh Bhagwandin, Peter I Folb, Pamisha Pillay, Reshma Gayaram

Open Access Research

Repeated treatment of recurrent uncomplicated Plasmodium falciparum malaria in Senegal with fixed-dose artesunate plus amodiaquine versus fixed-dose artemether plus lumefantrine: a randomized, open-label trial

Jean-Louis A Ndiaye, Babacar Faye, Ali Gueye, Roger Tine, Daouda Ndiaye, Corinne Tchania, Ibrahima Ndiaye, Aichatou Barry, Badara Cissé, Valérie Lameyre, Oumar Gaye

Open Access Methodology

Real-time PCR detection of Plasmodium directly from whole blood and filter paper samples

Brian J Taylor, Kimberly A Martin, Eliana Arango, Olga M Agudelo, Amanda Maestre, Stephanie K Yanow

Open Access Research

A cluster-randomized trial of mass drug administration with a gametocytocidal drug combination to interrupt malaria transmission in a low endemic area in Tanzania

Seif A Shekalaghe, Chris Drakeley, Sven van den Bosch, Roel ter Braak, Wouter van den Bijllaardt, Charles Mwanziva, Salimu Semvua, Alutu Masokoto, Frank Mosha, Karina Teelen, Rob Hermsen, Lucy Okell, Roly Gosling, Robert Sauerwein, Teun Bousema

Open Access Methodology

Development of ELISA-based methods to measure the anti-malarial drug chloroquine in plasma and in pharmaceutical formulations

Insaf F Khalil, Michael Alifrangis, Camilla Recke, Lotte C Hoegberg, Anita Ronn, Ib C Bygbjerg, Claus Koch

Open Access Research

Determinants of compliance with anti-vectorial protective measures among non-immune travellers during missions to tropical Africa

Emmanuel Sagui, Noémie Resseguier, Vanessa Machault, Lénaïck Ollivier, Eve Orlandi-Pradines, Gaetan Texier, Frédéric Pages, Remy Michel, Bruno Pradines, Sébastien Briolant, Alain Buguet, Catherine Tourette-Turgis, Christophe Rogier

Open Access Research

Malaria elimination in Isabel Province, Solomon Islands: establishing a surveillance-response system to prevent introduction and reintroduction of malaria

Matthew O'Sullivan, Geoffrey Kenilorea, Yuka Yamaguchi, Albino Bobogare, Landry Losi, Jo-An Atkinson, Andrew Vallely, Maxine Whittaker, Marcel Tanner, Rushika Wijesinghe

Open Access Research

Feasibility and acceptability of ACT for the community case management of malaria in urban settings in five African sites

Patricia Akweongo, Peter Agyei-Baffour, Morankar Sudhakar, Bertha N Simwaka, Amadou T Konaté, Philip B Adongo, Edmund NL Browne, Ayalew Tegegn, Doreen Ali, Abdoulaye Traoré, Mary Amuyunzu-Nyamongo, Franco Pagnoni, Guy Barnish

Open Access Research

Global gene expression profiling of Plasmodium falciparum in response to the anti-malarial drug pyronaridine

Kanyanan Kritsiriwuthinan, Sastra Chaotheing, Philip J Shaw, Chayaphat Wongsombat, Porntip Chavalitshewinkoon-Petmitr, Sumalee Kamchonwongpaisan

Open Access Case study

Socially-marketed rapid diagnostic tests and ACT in the private sector: ten years of experience in Cambodia

Shunmay Yeung, Edith Patouillard, Henrietta Allen, Duong Socheat

Open Access Research

Molecular markers of antifolate resistance in Plasmodium falciparum isolates from Luanda, Angola

Bianca E Gama, Guilhermina AL Pereira-Carvalho, Florbela JI Lutucuta Kosi, Natália K Almeida de Oliveira, Filomeno Fortes, Philip J Rosenthal, Virgílio E do Rosário, Cláudio Tadeu Daniel-Ribeiro, Maria de Fátima Ferreira-da-Cruz

Open Access Methodology

Rapid whole genome optical mapping of Plasmodium falciparum

Matthew C Riley, Benjamin C Kirkup Jr, Jake D Johnson, Emil P Lesho, Christian F Ockenhouse

Open Access Review

A review of mixed malaria species infections in anopheline mosquitoes

Mallika Imwong, Supatchara Nakeesathit, Nicholas PJ Day, Nicholas J White

Open Access Commentary

Treatment of imported severe malaria with artesunate instead of quinine - more evidence needed?

Jakob P Cramer, Rogelio López-Vélez, Gerd D Burchard, Martin P Grobusch, Peter J de Vries

Open Access Research

Recent increase of genetic diversity in Plasmodium vivax population in the Republic of Korea

Hajime Honma, Jung-Yeon Kim, Nirianne MQ Palacpac, Toshihiro Mita, Wonja Lee, Toshihiro Horii, Kazuyuki Tanabe

Open Access Research

Malaria and pre-eclampsia in an area with unstable malaria transmission in Central Sudan

Ishag Adam, Elhassan M Elhassan, Ahmed A Mohmmed, Magdi M Salih, Mustafa I Elbashir

Open Access Research

Congenital malaria in Urabá, Colombia

Juan G Piñeros-Jiménez, Gonzalo Álvarez, Alberto Tobón, Margarita Arboleda, Sonia Carrero, Silvia Blair

Open Access Research

Molecular markers of anti-malarial drug resistance in Lahj Governorate, Yemen: baseline data and implications

Reem A Mubjer, Ahmed A Adeel, Michael L Chance, Amir A Hassan

Open Access Research

Host candidate gene polymorphisms and clearance of drug-resistant Plasmodium falciparum parasites

Mahamadou Diakite, Eric A Achidi, Olivia Achonduh, Rachel Craik, Abdoulaye A Djimde, Marie-Solange B Evehe, Angie Green, Christina Hubbart, Muntasir Ibrahim, Anna Jeffreys, Baldip K Khan, Francis Kimani, Dominic P Kwiatkowski, Wilfred F Mbacham, Sabah Omar Jezan, Jean Bosco Ouedraogo, Kirk Rockett, Kate Rowlands, Nawal Tagelsir, Mamadou M Tekete, Issaka Zongo, Lisa C Ranford-Cartwright

Open Access Research

Dynamics of insecticide resistance in malaria vectors in Benin: first evidence of the presence of L1014S kdr mutation in Anopheles gambiae from West Africa

Innocent Djègbè, Olayidé Boussari, Aboubakar Sidick, Thibaud Martin, Hilary Ranson, Fabrice Chandre, Martin Akogbéto, Vincent Corbel

Open Access Research

Geo-additive modelling of malaria in Burundi

Hermenegilde Nkurunziza, Albrecht Gebhardt, Jürgen Pilz

Open Access Review

Review of the clinical pharmacokinetics of artesunate and its active metabolite dihydroartemisinin following intravenous, intramuscular, oral or rectal administration

Carrie A Morris, Stephan Duparc, Isabelle Borghini-Fuhrer, Donald Jung, Chang-Sik Shin, Lawrence Fleckenstein

Open Access Research

Early detection of malaria foci for targeted interventions in endemic southern Zambia

Ryan G Davis, Aniset Kamanga, Carlos Castillo-Salgado, Nnenna Chime, Sungano Mharakurwa, Clive Shiff

Open Access Research

Influence of environmental factors on the abundance of Anopheles farauti larvae in large brackish water streams in Northern Guadalcanal, Solomon Islands

Hugo Bugoro, Jeffery Hii, Tanya L Russell, Robert D Cooper, Benny KK Chan, Charles Iro'ofa, Charles Butafa, Allen Apairamo, Albino Bobogare, Cheng-Chen Chen

Open Access Research

Coma in fatal adult human malaria is not caused by cerebral oedema

Isabelle M Medana, Nicholas PJ Day, Navakanit Sachanonta, Nguyen TH Mai, Arjen M Dondorp, Emsri Pongponratn, Tran T Hien, Nicholas J White, Gareth DH Turner

Open Access Review

Genetic polymorphisms linked to susceptibility to malaria

Adel Driss, Jacqueline M Hibbert, Nana O Wilson, Shareen A Iqbal, Thomas V Adamkiewicz, Jonathan K Stiles

Open Access Research

Baseline results of the first malaria indicator survey in Iran at household level

Mahdi Mohammadi, Alireza Ansari-Moghaddam, Ahmad Raiesi, Fatemeh Rakhshani, Fatemeh Nikpour, Aliakbar Haghdost, Mansoor Ranjbar, Rahim Taghizadeh-Asl, Mohammad Sakeni, Reza Safari, Mehdi Saffari

Open Access Research

Comparative susceptibility to Plasmodium falciparum of the molecular forms M and S of Anopheles gambiae and Anopheles arabiensis

Mamadou O Ndiath, Anna Cohuet, Ablaye Gaye, Lassana Konate, Catherine Mazenot, Ousmane Faye, Christian Boudin, Cheikh Sokhna, Jean-François Trape

Open Access Case report

Reduced in vitro susceptibility to artemisinin derivatives associated with multi-resistance in a traveller returning from South-East Asia

Bruno Pradines, Lionel Bertaux, Christelle Pomares, Pascal Delaunay, Pierre Marty

Open Access Research

Cost analysis of school-based intermittent screening and treatment of malaria in Kenya

Thomas L Drake, George Okello, Kiambo Njagi, Katherine E Halliday, Matthew CH Jukes, Lindsay Mangham, Simon Brooker

Open Access Research

Methods to collect Anopheles mosquitoes and evaluate malaria transmission: A comparative study in two villages in Senegal

Mamadou O Ndiath, Catherine Mazenot, Ablaye Gaye, Lassana Konate, Charles Bouganali, Ousmane Faye, Cheikh Sokhna, Jean-Francois Trape

Open Access Research

Adherence to prescribed artemisinin-based combination therapy in Garissa and Bunyala districts, Kenya

Harriet Lawford, Dejan Zurovac, Laura O'Reilly, Sarah Hoibak, Alice Cowley, Stephen Munga, John Vulule, Elizabeth Juma, Robert W Snow, Richard Allan

Open Access Methodology

A new high-throughput method for simultaneous detection of drug resistance associated mutations in Plasmodium vivax dhfr, dhps and mdr1 genes

Céline Barnadas, David Kent, Lincoln Timinao, Jonah Iga, Laurie R Gray, Peter Siba, Ivo Mueller, Peter J Thomas, Peter A Zimmerman

Open Access Research

In vitro susceptibility to pyrimethamine of DHFR I164L single mutant Plasmodium falciparum

Valérie Andriantsoanirina, Rémy Durand, Bruno Pradines, Eric Baret, Christiane Bouchier, Arsène Ratsimbasoa, Didier Ménard

Open Access Research

Changes in vector species composition and current vector biology and behaviour will favour malaria elimination in Santa Isabel Province, Solomon Islands

Hugo Bugoro, Charlie Iro'ofa, Donna O Mackenzie, Allen Apairamo, Watson Hevalao, Sarah Corcoran, Albino Bobogare, Nigel W Beebe, Tanya L Russell, Cheng-Chen Chen, Robert D Cooper

Open Access Methodology

The parasite clearance curve

NJ White

Open Access Review

Effect of α+-thalassaemia on episodes of fever due to malaria and other causes: a community-based cohort study in Tanzania

Jacobien Veenemans, Esther JS Jansen, Amrish Y Baidjoe, Erasto V Mbugi, Ayşe Y Demir, Rob J Kraaijenhagen, Huub FJ Savelkoul, Hans Verhoef

Open Access Research

Population genetic structure of Anopheles arabiensis and Anopheles gambiae in a malaria endemic region of southern Tanzania

Kija R Ng'habi, Bart GJ Knols, Yoosook Lee, Heather M Ferguson, Gregory C Lanzaro

Open Access Research

Genetic polymorphism of merozoite surface protein-1 and merozoite surface protein-2 in Plasmodium falciparum isolates from Brazzaville, Republic of Congo

Pembe Issamou Mayengue, Mathieu Ndounga, Freddy Vladimir Malonga, Michel Bitemo, Francine Ntoumi

Open Access Research

Predictors of mosquito net use in Ghana

Carol A Baume, Ana Cláudia Franca-Koh

Open Access Research

Environmental, entomological, socioeconomic and behavioural risk factors for malaria attacks in Amerindian children of Camopi, French Guiana

Aurélia Stefani, Matthieu Hanf, Mathieu Nacher, Romain Girod, Bernard Carme

Open Access Commentary

Comparative decline in funding of European Commission malaria vaccine projects: what next for the European scientists working in this field?

Regitze L Thøgersen, Anthony A Holder, Adrian VS Hill, David E Arnot, Egeruan B Imoukhuede, Odile Leroy

Open Access Research

Increased interleukin-10 and interferon-γ levels in Plasmodium vivax malaria suggest a reciprocal regulation which is not altered by IL-10 gene promoter polymorphism

Tiago S Medina, Sheyla PT Costa, Maria D Oliveira, Ana M Ventura, José M Souza, Tassia F Gomes, Antonio CR Vallinoto, Marinete M Póvoa, João S Silva, Maristela G Cunha

Open Access Research

Effects of amodiaquine and artesunate on sulphadoxine-pyrimethamine pharmacokinetic parameters in children under five in Mali

Mamadou M Tekete, Sékou Toure, Alfia Fredericks, Abdoul H Beavogui, Cheick PO Sangare, Alicia Evans, Peter Smith, Hamma Maiga, Zoumana I Traore, Ogobara K Doumbo, Karen I Barnes, Abdoulaye A Djimde

Open Access Research

Evaluation of the Clearview® malaria pLDH malaria rapid diagnostic test in a non-endemic setting

Sandrine Houzé, Véronique Hubert, Dorit Pessler Cohen, Baruch Rivetz, Jacques Le Bras

Open Access Research

Malaria knowledge and long-lasting insecticidal net use in rural communities of central Côte d'Ivoire

Allassane F Ouattara, Giovanna Raso, Constant VA Edi, Jürg Utzinger, Marcel Tanner, Mamadou Dagnogo, Benjamin G Koudou

Open Access Methodology

Transgenic Plasmodium parasites stably expressing Plasmodium vivax dihydrofolate reductase-thymidylate synthase as in vitro and in vivo models for antifolate screening

Voravuth Somsak, Chairat Uthaipibull, Parichat Prommana, Somdet Srichairatanakool, Yongyuth Yuthavong, Sumalee Kamchonwongpaisan

Open Access Research

In vitro anti-plasmodial activity of Dicoma anomala subsp. gerrardii (Asteraceae): identification of its main active constituent, structure-activity relationship studies and gene expression profiling

John VW Becker, Marina M van der Merwe, Anna C van Brummelen, Pamisha Pillay, Bridget G Crampton, Edwin M Mmutlane, Chris Parkinson, Fanie R van Heerden, Neil R Crouch, Peter J Smith, Dalu T Mancama, Vinesh J Maharaj

Open Access Research

Falciparum malaria in young children of rural Burkina Faso: comparison of survey data in 1999 with 2009

Claudia Beiersmann, Mamadou Bountogo, Justin Tiendrébeogo, Manuela De Allegri, Valérie R Louis, Boubacar Coulibaly, Maurice Yé, Olaf Mueller

Open Access Research

Placental Plasmodium falciparum malaria infection: Operational accuracy of HRP2 rapid diagnostic tests in a malaria endemic setting

Daniel J Kyabayinze, James K Tibenderana, Mercy Nassali, Lynette K Tumwine, Clare Riches, Mark Montague, Helen Counihan, Prudence Hamade, Jean-Pierre Van Geertruyden, Sylvia Meek

Open Access Research

External quality assessment of malaria microscopy in the Democratic Republic of the Congo

Pierre Mukadi, Philippe Gillet, Albert Lukuka, Ben Atua, Simelo Kahodi, Jean Lokombe, Jean-Jacques Muyembe, Jan Jacobs

Open Access Research

Treatment guided by rapid diagnostic tests for malaria in Tanzanian children: safety and alternative bacterial diagnoses

George Mtove, Ilse CE Hendriksen, Ben Amos, Hedwiga Mrema, Victor Mandia, Alphaxard Manjurano, Florida Muro, Alma Sykes, Helena Hildenwall, Christopher JM Whitty, Hugh Reyburn

Open Access Research

A simple and fast method to exclude high Plasmodium falciparum parasitaemia in travellers with imported malaria

Tom van Gool, Marlies E van Wolfswinkel, Rob Koelewijn, Pieter PAM van Thiel, Jan Jacobs, Jaap J van Hellemond, Perry JJ van Genderen

Open Access Research

Ex vivo susceptibility of Plasmodium falciparum isolates from Dakar, Senegal, to seven standard anti-malarial drugs

Bécaye Fall, Silmane Diawara, Kowry Sow, Eric Baret, Bakary Diatta, Khadidiatou B Fall, Pape S Mbaye, Fatou Fall, Yaya Diémé, Christophe Rogier, Boubacar Wade, Raymond Bercion, Bruno Pradines

Open Access Research

The evolution of pyrimethamine resistant dhfr in Plasmodium falciparum of south-eastern Tanzania: comparing selection under SP alone vs SP+artesunate combination

Allen L Malisa, Richard J Pearce, Ben M Mutayoba, Salim Abdullah, Hassan Mshinda, Patrick S Kachur, Peter Bloland, Cally Roper

Open Access Research

Evidence for a useful life of more than three years for a polyester-based long-lasting insecticidal mosquito net in Western Uganda

Albert Kilian, Wilson Byamukama, Olivier Pigeon, John Gimnig, Francis Atieli, Lizette Koekemoer, Natacha Protopopoff

Open Access Research

Degradation of insecticides used for indoor spraying in malaria control and possible solutions

Mthokozisi M Sibanda, Walter W Focke, Frederick JWJ Labuschagne, Lumbidzani Moyo, Nontete S Nhlapo, Arjun Maity, Herminio Muiambo, Pedro Massinga Jr, Nico AS Crowther, Maureen Coetzee, Gordon WA Brindley

Open Access Research

Limited response of NK92 cells to Plasmodium falciparum-infected erythrocytes

Elisandra Grangeiro de Carvalho, Evelyn Böttger, Van Tong Hoang, Peter G Kremsner, Jürgen FJ Kun

Open Access Research

Baseline results of the first malaria indicator survey in Iran at the health facility level

Ahmad Raiesi, Fatemeh Nikpour, Alireza Ansari-Moghaddam, Mansoor Ranjbar, Fatemeh Rakhshani, Mahdi Mohammadi, Aliakbar Haghdost, Rahim Taghizadeh-Asl, Mohammad Sakeni, Reza Safari, Mehdi Saffari

Open Access Research

Laboratory demonstration of a prozone-like effect in HRP2-detecting malaria rapid diagnostic tests: implications for clinical management

Jennifer Luchavez, Joanne Baker, Sheila Alcantara, Vicente Belizario Jr, Qin Cheng, James S McCarthy, David Bell

Open Access Review

Use of mefloquine in children - a review of dosage, pharmacokinetics and tolerability data

Patricia Schlagenhauf, Miriam Adamcova, Loredana Regep, Martin T Schaerer, Sudhir Bansod, Hans-Georg Rhein

Open Access Research

Bayesian geostatistical modelling of malaria and lymphatic filariasis infections in Uganda: predictors of risk and geographical patterns of co-endemicity

Anna-Sofie Stensgaard, Penelope Vounatsou, Ambrose W Onapa, Paul E Simonsen, Erling M Pedersen, Carsten Rahbek, Thomas K Kristensen

Open Access Methodology

Theoretical investigation of malaria prevalence in two Indian cities using the response surface method

Sayantani Basu Roy, Ram Rup Sarkar, Somdatta Sinha

Open Access Case report

What clinicians who practice in countries reaching malaria elimination should be aware of: lessons learnt from recent experience in Sri Lanka

Ranjan Premaratna, Gowrie Galappaththy, Nilmini Chandrasena, Roshanthi Fernando, Thusha Nawasiwatte, Nilanthi R de Silva, H Janaka de Silva

Open Access Research

A thirteen-year analysis of Plasmodium falciparum populations reveals high conservation of the mutant pfcrt haplotype despite the withdrawal of chloroquine from national treatment guidelines in Gabon

Matthias Frank, Nicola Lehners, Pembe I Mayengue, Julian Gabor, Matthias Dal-Bianco, David U Kombila, Ghyslain Mombo Ngoma, Christian Supan, Bertrand Lell, Francine Ntoumi, Martin P Grobusch, Klaus Dietz, Peter G Kremsner

Open Access Research

Cost-effectiveness of intermittent preventive treatment of malaria in infants (IPTi) for averting anaemia in Gabon: a comparison between intention to treat and according to protocol analyses

Elisa Sicuri, Prosper Biao, Guy Hutton, Fabrizio Tediosi, Clara Menendez, Bertrand Lell, Peter Kremsner, Lesong Conteh, Martin P Grobusch

Open Access Research

Association of ABO blood group with severe falciparum malaria in adults: case control study and meta-analysis

Aditya K Panda, Santosh K Panda, Aditya N Sahu, Rina Tripathy, Balachandran Ravindran, Bidyut K Das

Open Access Research

Conditions of malaria transmission in Dakar from 2007 to 2010

Libasse Gadiaga, Vanessa Machault, Frédéric Pagès, Abdoulaye Gaye, Fanny Jarjaval, Lydie Godefroy, Birane Cissé, Jean-Pierre Lacaux, Cheikh Sokhna, Jean-François Trape, Christophe Rogier

Open Access Research

Identification, characterization and antigenicity of the Plasmodium vivax rhoptry neck protein 1 (Pv RON1)

Darwin A Moreno-Perez, Marjorie Montenegro, Manuel E Patarroyo, Manuel A Patarroyo

Open Access Research

Assessment of the knowledge of graphical symbols labelled on malaria rapid diagnostic tests in four international settings

Veerle Hermans, Lianet Monzote, Björn Van den Sande, Pierre Mukadi, Thai Sopheak, Philippe Gillet, Jan Jacobs

Open Access Methodology

The ACTwatch project: methods to describe anti-malarial markets in seven countries

Tanya Shewchuk, Kathryn A O'Connell, Catherine Goodman, Kara Hanson, Steven Chapman, Desmond Chavasse

Open Access Research

Low quality of routine microscopy for malaria at different levels of the health system in Dar es Salaam

Judith Kahama-Maro, Valerie D'Acremont, Deo Mtasiwa, Blaise Genton, Christian Lengeler

Open Access Commentary

A national policy for malaria elimination in Swaziland: a first for sub-Saharan Africa

Simon Kunene, Allison A Phillips, Roly D Gosling, Deepika Kandula, Joseph M Novotny

Open Access Research

Accessibility, availability and affordability of anti-malarials in a rural district in Kenya after implementation of a national subsidy scheme

Nathan Smith, Andrew Obala, Chrispinus Simiyu, Diana Menya, Barasa Khwa-Otsyula, Wendy Prudhomme O'Meara

Open Access Research

Decreasing incidence of severe malaria and community-acquired bacteraemia among hospitalized children in Muheza, north-eastern Tanzania, 2006-2010

George Mtove, Ben Amos, Behzad Nadjm, Ilse CE Hendriksen, Arjen M Dondorp, Abraham Mwambuli, Deok Ryun Kim, R Leon Ochiai, John D Clemens, Lorenz von Seidlein, Hugh Reyburn, Jacqueline Deen

Open Access Research

Considerations on the use of nucleic acid-based amplification for malaria parasite detection

Stéphane Proux, Rossarin Suwanarusk, Marion Barends, Julien Zwang, Ric N Price, Mara Leimanis, Lily Kiricharoen, Natthapon Laochan, Bruce Russell, François Nosten, Georges Snounou

Open Access Methodology

Development of standardized laboratory methods and quality processes for a phase III study of the RTS, S/AS01 candidate malaria vaccine

Christine Swysen, Johan Vekemans, Myriam Bruls, Sunny Oyakhirome, Chris Drakeley, Peter Kremsner, Brian Greenwood, Opokua Ofori-Anyinam, Brenda Okech, Tonya Villafana, Terrell Carter, Barbara Savarese, Adriano Duse, Andrea Reijman, Charlotte Ingram, John Frean, Bernhards Ogutu

Open Access Methodology

Assessment of severe malaria in a multicenter, phase III, RTS, S/AS01 malaria candidate vaccine trial: case definition, standardization of data collection and patient care

Johan Vekemans, Kevin Marsh, Brian Greenwood, Amanda Leach, William Kabore, Solange Soulanoudjingar, Kwaku Poku Asante, Daniel Ansong, Jennifer Evans, Jahit Sacarlal, Philip Bejon, Portia Kamthunzi, Nahya Salim, Patricia Njuguna, Mary J Hamel, Walter Otieno, Samwel Gesase, David Schellenberg

Open Access Research

Monitoring fever treatment behaviour and equitable access to effective medicines in the context of initiatives to improve ACT access: baseline results and implications for programming in six African countries

Megan Littrell, Hellen Gatakaa, Illah Evance, Stephen Poyer, Julius Njogu, Tsione Solomon, Erik Munroe, Steven Chapman, Catherine Goodman, Kara Hanson, Cyprien Zinsou, Louis Akulayi, Jacky Raharinjatovo, Ekundayo Arogundade, Peter Buyungo, Felton Mpasela, Cherifatou Bello Adjibabi, Jean Angbalu Agbango, Benjamin Fanomezana Ramarosandratana, Babajide Coker, Denis Rubahika, Busiku Hamainza, Tanya Shewchuk, Desmond Chavasse, Kathryn A O'Connell

Open Access Research

Case management of malaria fever in Cambodia: results from national anti-malarial outlet and household surveys

Megan Littrell, Hellen Gatakaa, Sochea Phok, Henrietta Allen, Shunmay Yeung, Char Meng Chuor, Lek Dysoley, Duong Socheat, Angus Spiers, Chris White, Tanya Shewchuk, Desmond Chavasse, Kathryn A O'Connell

Open Access Research

Malaria with neurological involvement in Ugandan children: effect on cognitive ability, academic achievement and behaviour

Paul Bangirana, Seggane Musisi, Michael J Boivin, Anna Ehnvall, Chandy C John, Tracy L Bergemann, Peter Allebeck

Open Access Research

State of malaria diagnostic testing at clinical laboratories in the United States, 2010: a nationwide survey

Francisca A Abanyie, Paul M Arguin, Julie Gutman

Open Access Research

Got ACTs? Availability, price, market share and provider knowledge of anti-malarial medicines in public and private sector outlets in six malaria-endemic countries

Kathryn A O'Connell, Hellen Gatakaa, Stephen Poyer, Julius Njogu, Illah Evance, Erik Munroe, Tsione Solomon, Catherine Goodman, Kara Hanson, Cyprien Zinsou, Louis Akulayi, Jacky Raharinjatovo, Ekundayo Arogundade, Peter Buyungo, Felton Mpasela, Chérifatou Bello Adjibabi, Jean Angbalu Agbango, Benjamin Fanomezana Ramarosandratana, Babajide Coker, Denis Rubahika, Busiku Hamainza, Steven Chapman, Tanya Shewchuk, Desmond Chavasse

Open Access Research

Mitochondrial NAD+-dependent malic enzyme from Anopheles stephensi: a possible novel target for malaria mosquito control

Jennifer Pon, Eleonora Napoli, Shirley Luckhart, Cecilia Giulivi

Open Access Review

Systematic review and meta-analysis: rapid diagnostic tests versus placental histology, microscopy and PCR for malaria in pregnant women

Johanna H Kattenberg, Eleanor A Ochodo, Kimberly R Boer, Henk DFH Schallig, Petra F Mens, Mariska MG Leeflang

Open Access Research

Multivariate modelling with 1H NMR of pleural effusion in murine cerebral malaria

Soumita Ghosh, Arjun Sengupta, Shobhona Sharma, Haripalsingh M Sonawat

Open Access Research

Vivax malaria in Mauritania includes infection of a Duffy-negative individual

Nathalie Wurtz, Khadijetou Mint Lekweiry, Hervé Bogreau, Bruno Pradines, Christophe Rogier, Ali Ould Mohamed Salem Boukhary, Jamal Eddine Hafid, Mohamed Salem Ould Ahmedou Salem, Jean-François Trape, Leonardo K Basco, Sébastien Briolant

Open Access Research

Central venous catheter use in severe malaria: time to reconsider the World Health Organization guidelines?

Josh Hanson, Sophia WK Lam, Sanjib Mohanty, Shamshul Alam, Md Mahtab Uddin Hasan, Sue J Lee, Marcus J Schultz, Prakaykaew Charunwatthana, Sophie Cohen, Ashraf Kabir, Saroj Mishra, Nicholas PJ Day, Nicholas J White, Arjen M Dondorp

Open Access Research

Intravenous pharmacokinetics, oral bioavailability, dose proportionality and in situ permeability of anti-malarial lumefantrine in rats

Wahajuddin, Sheelendra P Singh, Kanumuri SR Raju, Asad Nafis, Sunil K Puri, Girish K Jain

Open Access Review

Costs and cost-effectiveness of malaria control interventions - a systematic review

Michael T White, Lesong Conteh, Richard Cibulskis, Azra C Ghani

Open Access Research

Combining indoor residual spraying with chlorfenapyr and long-lasting insecticidal bed nets for improved control of pyrethroid-resistant Anopheles gambiae: an experimental hut trial in Benin

Corine Ngufor, Raphael N'Guessan, Pelagie Boko, Abibatou Odjo, Estelle Vigninou, Alex Asidi, Martin Akogbeto, Mark Rowland

Open Access Research

Sexual recombination is a signature of a persisting malaria epidemic in Peru

Patrick L Sutton, Lindsay P Torres, OraLee H Branch

Open Access Research

Variations of insecticide residual bio-efficacy on different types of walls: results from a community-based trial in south Cameroon

Josiane Etang, Philippe Nwane, Jean Arthur Mbida, Michael Piameu, Blaise Manga, Daniel Souop, Parfait Awono-Ambene

Open Access Methodology

Standardizing the measurement of parasite clearance in falciparum malaria: the parasite clearance estimator

Jennifer A Flegg, Philippe J Guerin, Nicholas J White, Kasia Stepniewska

Open Access Research

Changing individual-level risk factors for malaria with declining transmission in southern Zambia: a cross-sectional study

Catherine G Sutcliffe, Tamaki Kobayashi, Harry Hamapumbu, Timothy Shields, Aniset Kamanga, Sungano Mharakurwa, Philip E Thuma, Gregory Glass, William J Moss

Open Access Methodology

In vitro culture of Plasmodium berghei-ANKA maintains infectivity of mouse erythrocytes inducing cerebral malaria

Ronan Jambou, Fatima El-Assaad, Valery Combes, Georges E Grau

Open Access Research

Epidemiology of imported malaria among children and young adults in Barcelona (1990-2008)

Mireia Garcia-Villarrubia, Juan-Pablo Millet, Patricia Garcia de Olalla, Joaquim Gascón, Victoria Fumadó, Jordi Gómez i Prat, Begoña Treviño, María-Jesús Pinazo, Juan Cabezos, José Muñoz, Francesc Zarzuela, Joan A Caylà

Open Access Research

Pharmaceutical services for endemic situations in the Brazilian Amazon: organization of services and prescribing practices for Plasmodium vivax and Plasmodium falciparum non-complicated malaria in high-risk municipalities

Martha C Suárez-Mutis, Paula P de Souza, Letícia F Freitas, Elaine S Miranda, Mônica R Campos, Claudia GS Osorio-de-Castro

Open Access Methodology

Automated and unsupervised detection of malarial parasites in microscopic images

Yashasvi Purwar, Sirish L Shah, Gwen Clarke, Areej Almugairi, Atis Muehlenbachs

Open Access Research

Use of a pLDH-based dipstick in the diagnostic and therapeutic follow-up of malaria patients in Mali

Amed Ouattara, Safiatou Doumbo, Renion Saye, Abdoul H Beavogui, Boubacar Traoré, Abdoulaye Djimdé, Amadou Niangaly, Kassoum Kayentao, Mouctar Diallo, Ogobara K Doumbo, Mahamadou A Thera

Open Access Research

Factors associated with mosquito net use by individuals in households owning nets in Ethiopia

Patricia M Graves, Jeremiah M Ngondi, Jimee Hwang, Asefaw Getachew, Teshome Gebre, Aryc W Mosher, Amy E Patterson, Estifanos B Shargie, Zerihun Tadesse, Adam Wolkon, Richard Reithinger, Paul M Emerson, Frank O Richards Jr

Open Access Research

Plasmodium vivax lineages: geographical distribution, tandem repeat polymorphism, and phylogenetic relationship

Surendra K Prajapati, Hema Joshi, Sneh Shalini, Manuel A Patarroyo, Rossarin Suwanarusk, Ashwani Kumar, Surya K Sharma, Alex Eapen, Vas Dev, Rajendra M Bhatt, Neena Valecha, Francois Nosten, Moshahid A Rizvi, Aditya P Dash

Open Access Research

Antibiotic use among patients with febrile illness in a low malaria endemicity setting in Uganda

Vincent Batwala, Pascal Magnussen, Fred Nuwaha

Open Access Research

Broad inhibition of plasmodium falciparum cytoadherence by (+)-epigallocatechin gallate

Pradeep R Patil, Sandra Gemma, Giuseppe Campiani, Alister G Craig

Open Access Research

Association of ADAMTS13 polymorphism with cerebral malaria

Sirima Kraisin, Izumi Naka, Jintana Patarapotikul, Duangdao Nantakomol, Pornlada Nuchnoi, Hathairad Hananantachai, Naoyuki Tsuchiya, Jun Ohashi

Open Access Research

Cluster-randomized study of intermittent preventive treatment for malaria in infants (IPTi) in southern Tanzania: evaluation of impact on survival

Joanna RM Armstrong Schellenberg, Werner Maokola, Kizito Shirima, Fatuma Manzi, Mwifadhi Mrisho, Adiel Mushi, Pedro Alonso, Hassan Mshinda, Marcel Tanner, David M Schellenberg

Open Access Research

Poor quality vital anti-malarials in Africa - an urgent neglected public health priority

Paul N Newton, Michael D Green, Dallas C Mildenhall, Aline Plançon, Henry Nettey, Leonard Nyadong, Dana M Hostetler, Isabel Swamidoss, Glenn A Harris, Kristen Powell, Ans E Timmermans, Abdinasir A Amin, Stephen K Opuni, Serge Barbereau, Claude Faurant, Ray CW Soong, Kevin Faure, Jonarthan Thevanayagam, Peter Fernandes, Harparkash Kaur, Brian Angus, Kasia Stepniewska, Philippe J Guerin, Facundo M Fernández

Open Access Research

Immunogenicity of a virosomally-formulated Plasmodium falciparum GLURP-MSP3 chimeric protein-based malaria vaccine candidate in comparison to adjuvanted formulations

Marco Tamborrini, Sabine A Stoffel, Nicole Westerfeld, Mario Amacker, Michael Theisen, Rinaldo Zurbriggen, Gerd Pluschke

Open Access Research

Mapping of mosquito breeding sites in malaria endemic areas in Pos Lenjang, Kuala Lipis, Pahang, Malaysia

Rohani Ahmad, Wan NWM Ali, Zurainee M Nor, Zamree Ismail, Azahari A Hadi, Mohd N Ibrahim, Lee H Lim

Open Access Research

Assessing healthcare providers' knowledge and practices relating to insecticide-treated nets and the prevention of malaria in Ghana, Laos, Senegal and Tanzania

Steven J Hoffman, G Emmanuel Guindon, John N Lavis, Godwin D Ndossi, Eric JA Osei, Mintou Fall Sidibe, Boungnong Boupha

Open Access Research

Drug resistance associated genetic polymorphisms in Plasmodium falciparum and Plasmodium vivax collected in Honduras, Central America

Irina T Jovel, Rosa E Mejía, Engels Banegas, Rita Piedade, Jackeline Alger, Gustavo Fontecha, Pedro E Ferreira, Maria I Veiga, Irma G Enamorado, Anders Bjorkman, Johan Ursing

Open Access Research

Adherence to Plasmodium vivax malaria treatment in the Brazilian Amazon Region

Elza A Pereira, Edna AY Ishikawa, Cor JF Fontes

Open Access Opinion

Larval source management for malaria control in Africa: myths and reality

Ulrike Fillinger, Steven W Lindsay

Open Access Research

A new world malaria map: Plasmodium falciparum endemicity in 2010

Peter W Gething, Anand P Patil, David L Smith, Carlos A Guerra, Iqbal RF Elyazar, Geoffrey L Johnston, Andrew J Tatem, Simon I Hay

Open Access Research

Association of sub-microscopic malaria parasite carriage with transmission intensity in north-eastern Tanzania

Alphaxard Manjurano, Lucy Okell, Tedson Lukindo, Hugh Reyburn, Raimos Olomi, Cally Roper, Taane G Clark, Sarah Joseph, Eleanor M Riley, Chris Drakeley

Open Access Research

Evaluation of immunity against malaria using luciferase-expressing Plasmodium berghei parasites

Ivo Ploemen, Marije Behet, Krystelle Nganou-Makamdop, Geert-Jan van Gemert, Else Bijker, Cornelus Hermsen, Robert Sauerwein

Open Access Research

The use of paediatric artemisinin combinations in sub-Saharan Africa: a snapshot questionnaire survey of health care personnel

Selidji T Agnandji, Florian Kurth, Jose F Fernandes, Solange S Soulanoudjingar, Beatrice P Abossolo, Ghyslain Mombo-Ngoma, Arti Basra, Raquel González, Gondo Kizito, Pembe I Mayengue, Lorenz Auer-Hackenberg, Saadou Issifou, Bertrand Lell, Ayola A Adegnika, Michael Ramharter

Open Access Research

Plasmodium falciparum population dynamics during the early phase of anti-malarial drug treatment in Tanzanian children with acute uncomplicated malaria

Anja M Carlsson, Billy E Ngasala, Sabina Dahlström, Christopher Membi, Isabel M Veiga, Lars Rombo, Salim Abdulla, Zul Premji, J Pedro Gil, Anders Björkman, Andreas Mårtensson

Open Access Research

Genetic analysis of the merozoite surface protein-1 block 2 allelic types in Plasmodium falciparum clinical isolates from Lao PDR

Naly Khaminsou, Onanong Kritpetcharat, Jureerut Daduang, Lertchai Charerntanyarak, Panutas Kritpetcharat

Open Access Research

Prescription practices and availability of artemisinin monotherapy in India: where do we stand?

Neelima Mishra, Anupkumar R Anvikar, Naman K Shah, Vineet Kumar Kamal, Surya Kant Sharma, Harish Chandra Srivastava, Manoj Kumar Das, Khageswar Pradhan, Hemant Kumar, Yogendra K Gupta, Pooja Gupta, Aditya Prasad Dash, Neena Valecha

Open Access Research

Suppression of circulating IgD+CD27+ memory B cells in infants living in a malaria-endemic region of Kenya

Amolo S Asito, Erwan Piriou, Walter GZO Jura, Collins Ouma, Peter S Odada, Sidney Ogola, Nancy Fiore, Rosemary Rochford

Open Access Research

Fresh, dried or smoked? repellent properties of volatiles emitted from ethnomedicinal plant leaves against malaria and yellow fever vectors in Ethiopia

Fitsum Fikru Dube, Kassahun Tadesse, Göran Birgersson, Emiru Seyoum, Habte Tekie, Rickard Ignell, Sharon R Hill

Open Access Research

Impact of combining intermittent preventive treatment with home management of malaria in children less than 10 years in a rural area of Senegal: a cluster randomized trial

Roger CK Tine, Babacar Faye, Cheikh T Ndour, Jean L Ndiaye, Magatte Ndiaye, Charlemagne Bassene, Pascal Magnussen, Ib C Bygbjerg, Khadim Sylla, Jacques D Ndour, Oumar Gaye

Open Access Research

The role of age, ethnicity and environmental factors in modulating malaria risk in Rajasthali, Bangladesh

Ubydul Haque, Ricardo J Soares Magalhães, Dipak Mitra, Korine N Kolivras, Wolf-Peter Schmidt, Rashidul Haque, Gregory E Glass

Open Access Research

Prevalence and distribution of glucose-6-phosphate dehydrogenase (G6PD) variants in Thai and Burmese populations in malaria endemic areas of Thailand

Papichaya Phompradit, Jiraporn Kuesap, Wanna Chaijaroenkul, Ronnatrai Rueangweerayut, Yaowaluck Hongkaew, Rujira Yamnuan, Kesara Na-Bangchang

Open Access Research

Plasma levels of angiopoietin-1 and -2 predict cerebral malaria outcome in Central India

Vidhan Jain, Naomi W Lucchi, Nana O Wilson, Anna J Blackstock, Avinash C Nagpal, Pradeep K Joel, Mrigendra P Singh, Venkatachalam Udhayakumar, Jonathan K Stiles, Neeru Singh

Open Access Research

What drives community adherence to indoor residual spraying (IRS) against malaria in Manhiça district, rural Mozambique: a qualitative study

Khátia Munguambe, Robert Pool, Catherine Montgomery, Carlos Bavo, Ariel Nhacolo, Lina Fiosse, Charfudin Sacoor, Delino Nhalungo, Samuel Mabunda, Eusébio Macete, Pedro Alonso

Open Access Research

Impact of insecticide-treated bed nets on malaria transmission indices on the south coast of Kenya

Francis M Mutuku, Charles H King, Peter Mungai, Charles Mbogo, Joseph Mwangangi, Eric M Muchiri, Edward D Walker, Uriel Kitron

Open Access Research

Early and extensive CD55 loss from red blood cells supports a causal role in malarial anaemia

Moses Gwamaka, Michal Fried, Gonzalo Domingo, Patrick E Duffy

Open Access Research

Global host metabolic response to Plasmodium vivax infection: a 1H NMR based urinary metabonomic study

Arjun Sengupta, Soumita Ghosh, Angika Basant, Suhas Malusare, Parul Johri, Sulabha Pathak, Shobhona Sharma, Haripalsingh M Sonawat

Open Access Research

Similar efficacy and safety of artemether-lumefantrine (Coartem®) in African infants and children with uncomplicated falciparum malaria across different body weight ranges

Quique Bassat, Raquel González, Sónia Machevo, Alain Nahum, John Lyimo, Hamma Maiga, Andreas Mårtensson, Mahfudh Bashraheil, Peter Ouma, David Ubben, Verena Walter, Obiyo Nwaiwu, Chemtai Kipkeu, Gilbert Lefèvre, Bernhards Ogutu, Clara Menéndez

Open Access Commentary

The relevance of non-human primate and rodent malaria models for humans

Jean Langhorne, Pierre Buffet, Mary Galinski, Michael Good, John Harty, Didier Leroy, Maria M Mota, Erica Pasini, Laurent Renia, Eleanor Riley, Monique Stins, Patrick Duffy

Open Access Research

Improvement of a synthetic lure for Anopheles gambiae using compounds produced by human skin microbiota

Niels O Verhulst, Phoebe A Mbadi, Gabriella Bukovinszkiné Kiss, Wolfgang R Mukabana, Joop JA van Loon, Willem Takken, Renate C Smallegange

Open Access Research

Blood transfer devices for malaria rapid diagnostic tests: evaluation of accuracy, safety and ease of use

Heidi Hopkins, Wellington Oyibo, Jennifer Luchavez, Mary Lorraine Mationg, Caroline Asiimwe, Audrey Albertini, Iveth J González, Michelle L Gatton, David Bell

Open Access Research

Prevalence of Plasmodium falciparum infection in asymptomatic rural Gabonese populations

Dieudonné Nkoghe, Jean-Paul Akue, Jean-Paul Gonzalez, Eric M Leroy

Open Access Review

Primaquine in vivax malaria: an update and review on management issues

Deepika Fernando, Chaturaka Rodrigo, Senaka Rajapakse

Open Access Research

Changes in health workers' malaria diagnosis and treatment practices in Kenya

Elizabeth Juma, Dejan Zurovac

Open Access Research

A trial of intermittent preventive treatment and home-based management of malaria in a rural area of The Gambia

Sanie Sesay, Paul Milligan, Ensa Touray, Maimuna Sowe, Emily L Webb, Brian M Greenwood, Kalifa A Bojang

Open Access Research

Exploring provider and community responses to the new malaria diagnostic and treatment regime in Solomon Islands

Rushika S Wijesinghe, Jo-An M Atkinson, Albino Bobogare, Lyndes Wini, Maxine Whittaker

Open Access Research

Global response of Plasmodium falciparum to hyperoxia: a combined transcriptomic and proteomic approach

Marylin Torrentino-Madamet, Lionel Alméras, Jérôme Desplans, Yannick Le Priol, Maya Belghazi, Matthieu Pophillat, Patrick Fourquet, Yves Jammes, Daniel Parzy

Open Access Research

Genetic and phenotypic variation of the malaria vector Anopheles atroparvus in southern Europe

José L Vicente, Carla A Sousa, Bulent Alten, Selim S Caglar, Elena Falcutá, José M Latorre, Celine Toty, Hélène Barré, Berna Demirci, Marco Di Luca, Luciano Toma, Ricardo Alves, Patrícia Salgueiro, Teresa L Silva, Maria D Bargues, Santiago Mas-Coma, Daniela Boccolini, Roberto Romi, Gabriela Nicolescu, Virgílio E do Rosário, Nurdan Ozer, Didier Fontenille, João Pinto

Open Access Research

Using rapid diagnostic tests as source of malaria parasite DNA for molecular analyses in the era of declining malaria prevalence

Deus S Ishengoma, Sudi Lwitiho, Rashid A Madebe, Nyagonde Nyagonde, Ola Persson, Lasse S Vestergaard, Ib C Bygbjerg, Martha M Lemnge, Michael Alifrangis

Open Access Research

Evaluation of the rapid diagnostic test SDFK40 (Pf-pLDH/pan-pLDH) for the diagnosis of malaria in a non-endemic setting

Jessica Maltha, Philippe Gillet, Lieselotte Cnops, Emmanuel Bottieau, Marjan Van Esbroeck, Cathrien Bruggeman, Jan Jacobs

Open Access Research

Use of the atmospheric generators for capnophilic bacteria Genbag-CO2 for the evaluation of in vitro Plasmodium falciparum susceptibility to standard anti-malarial drugs

Aurélie Pascual, Leonardo K Basco, Eric Baret, Rémy Amalvict, Dominique Travers, Christophe Rogier, Bruno Pradines

Open Access Research

Lactase persistence genotypes and malaria susceptibility in Fulani of Mali

A Inkeri Lokki, Irma Järvelä, Elisabeth Israelsson, Bakary Maiga, Marita Troye-Blomberg, Amagana Dolo, Ogobara K Doumbo, Seppo Meri, Ville Holmberg

Open Access Research

Spatial and temporal variation in the kdr allele L1014S in Anopheles gambiae s.s. and phenotypic variability in susceptibility to insecticides in Western Kenya

Derrick K Mathias, Eric Ochomo, Francis Atieli, Maurice Ombok, M Nabie Bayoh, George Olang, Damaris Muhia, Luna Kamau, John M Vulule, Mary J Hamel, William A Hawley, Edward D Walker, John E Gimnig

Open Access Commentary

EU-funded malaria research under the 6th and 7th Framework Programmes for research and technological development

Andreas Holtel, Marita Troye-Blomberg, Inmaculada Penas-Jimenez

Open Access Research

Raised temperatures over the Kericho tea estates: revisiting the climate in the East African highlands malaria debate

Judith A Omumbo, Bradfield Lyon, Samuel M Waweru, Stephen J Connor, Madeleine C Thomson

Open Access Research

Anaemia in a phase 2 study of a blood stage falciparum malaria vaccine

Ruth D Ellis, Michael P Fay, Issaka Sagara, Alassane Dicko, Kazutoyo Miura, Merepen A Guindo, Aldiouma Guindo, Mahamadou S Sissoko, Ogobara K Doumbo, Dapa Diallo

Open Access Research

Plasmodium falciparum liver stage antigen-1 is cross-linked by tissue transglutaminase

William S Nicoll, John B Sacci, Carlo Rodolfo, Giuseppina Di Giacomo, Mauro Piacentini, Zoe JM Holland, Christian Doerig, Michael R Hollingdale, David E Lanar

Open Access Research

Chlorfenapyr: a new insecticide with novel mode of action can control pyrethroid resistant malaria vectors

Kamaraju Raghavendra, Tapan K Barik, Poonam Sharma, Rajendra M Bhatt, Harish C Srivastava, Uragayala Sreehari, Aditya P Dash

Open Access Research

var gene transcription and PfEMP1 expression in the rosetting and cytoadhesive Plasmodium falciparum clone FCR3S1.2

Letusa Albrecht, Kirsten Moll, Karin Blomqvist, Johan Normark, Qijun Chen, Mats Wahlgren

Open Access Research

Prevalence of resistance associated polymorphisms in Plasmodium falciparum field isolates from southern Pakistan

Najia Karim Ghanchi, Johan Ursing, Mohammad A Beg, Maria I Veiga, Sana Jafri, Andreas Mårtensson

Open Access Research

Evaluation of prevalence's of pfdhfr and pfdhps mutations in Angola

Filomeno Fortes, Rafael Dimbu, Paula Figueiredo, Zoraima Neto, Virgílio E do Rosário, Dinora Lopes

Open Access Research

School-based surveys of malaria in Oromia Regional State, Ethiopia: a rapid survey method for malaria in low transmission settings

Ruth A Ashton, Takele Kefyalew, Gezahegn Tesfaye, Rachel L Pullan, Damtew Yadeta, Richard Reithinger, Jan H Kolaczinski, Simon Brooker

Open Access Research

Access to artesunate-amodiaquine, quinine and other anti-malarials: policy and markets in Burundi

John H Amuasi, Graciela Diap, Samuel Blay-Nguah, Isaac Boakye, Patrick E Karikari, Baza Dismas, Jeanne Karenzo, Lievin Nsabiyumva, Karly S Louie, Jean-René Kiechel

Open Access Research

Reductions in malaria and anaemia case and death burden at hospitals following scale-up of malaria control in Zanzibar, 1999-2008

Maru W Aregawi, Abdullah S Ali, Abdul-wahiyd Al-mafazy, Fabrizio Molteni, Samson Katikiti, Marian Warsame, Ritha JA Njau, Ryuichi Komatsu, Eline Korenromp, Mehran Hosseini, Daniel Low-Beer, Anders Bjorkman, Umberto D'Alessandro, Marc Coosemans, Mac Otten

Open Access Research

Reduced risk for placental malaria in iron deficient women

Edward L Senga, Gregory Harper, Gibby Koshy, Peter N Kazembe, Bernard J Brabin

Open Access Research

Stability-indicating HPLC-DAD/UV-ESI/MS impurity profiling of the anti-malarial drug lumefantrine

Mathieu Verbeken, Sultan Suleman, Bram Baert, Elien Vangheluwe, Sylvia Van Dorpe, Christian Burvenich, Luc Duchateau, Frans H Jansen, Bart De Spiegeleer

Open Access Research

Temporal correlation analysis between malaria and meteorological factors in Motuo County, Tibet

Fang Huang, Shuisen Zhou, Shaosen Zhang, Hongju Wang, Linhua Tang

Open Access Research

Effect of HIV infection on the acute antibody response to malaria antigens in children: an observational study

Daniel KM Muema, Francis M Ndungu, Samson M Kinyanjui, James A Berkley

Open Access Research

Artemisinin-induced parasite dormancy: a plausible mechanism for treatment failure

Andrea Codd, Franka Teuscher, Dennis E Kyle, Qin Cheng, Michelle L Gatton

Open Access Research

Randomized controlled trials of malaria intervention trials in Africa, 1948 to 2007: a descriptive analysis

Vittoria Lutje, Annette Gerritsen, Nandi Siegfried

Open Access Research

Effectiveness of artemether-lumefantrine provided by community health workers in under-five children with uncomplicated malaria in rural Tanzania: an open label prospective study

Billy E Ngasala, Maja Malmberg, Anja M Carlsson, Pedro E Ferreira, Max G Petzold, Daniel Blessborn, Yngve Bergqvist, José P Gil, Zul Premji, Andreas Mårtensson

Open Access Research

Development of a new version of the Liverpool Malaria Model. II. Calibration and validation for West Africa

Volker Ermert, Andreas H Fink, Anne E Jones, Andrew P Morse

Open Access Research

Low prevalence of Plasmodium falciparum antigenaemia among asymptomatic HAART-treated adults in an urban cohort in Uganda

Damalie Nakanjako, Agnes N Kiragga, Barbara Castelnuovo, Daniel J Kyabayinze, Moses R Kamya

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Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

26.04.2024 Hüft-TEP Nachrichten

Ob bei einer Notfalloperation nach Schenkelhalsfraktur eine Hemiarthroplastik oder eine totale Endoprothese (TEP) eingebaut wird, sollte nicht allein vom Alter der Patientinnen und Patienten abhängen. Auch über 90-Jährige können von der TEP profitieren.

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

25.04.2024 Hypotonie Nachrichten

Wenn unter einer medikamentösen Hochdrucktherapie der diastolische Blutdruck in den Keller geht, steigt das Risiko für schwere kardiovaskuläre Ereignisse: Darauf deutet eine Sekundäranalyse der SPRINT-Studie hin.

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

Insektenstiche sind bei Erwachsenen die häufigsten Auslöser einer Anaphylaxie. Einen wirksamen Schutz vor schweren anaphylaktischen Reaktionen bietet die allergenspezifische Immuntherapie. Jedoch kommt sie noch viel zu selten zum Einsatz.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

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