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Medical Oncology

Ausgabe 3/2013

Inhalt (91 Artikel)

Original Paper

High SKIP expression is correlated with poor prognosis and cell proliferation of hepatocellular carcinoma

Guoliang Liu, Xiaodong Huang, Xiaopeng Cui, Jing Zhang, Lixian Wei, Runzhou Ni, Cuihua Lu

Original Paper

Association between main Caspase Gene Polymorphisms and the Susceptibility and Prognosis of Colorectal Cancer

Zhiwei Wu, Ye Li, Shuying Li, Lin Zhu, Guangxiao Li, Zhifu Yu, Xiaojuan Zhao, Jie Ge, Binbin Cui, Xinshu Dong, Suli Tian, Fulan Hu, Yashuang Zhao

Original Paper

Clinical significance of integrin αvβ6 expression effects on gastric carcinoma invasiveness and progression via cancer-associated fibroblasts

Zhuonan Zhuang, Ruiling Zhou, Xiaozhou Xu, Tian Tian, Yi Liu, Yanfeng Liu, Peilong Lian, Jiayong Wang, Kesen Xu

Original Paper

Tau proteins expressions in advanced breast cancer and its significance in taxane-containing neoadjuvant chemotherapy

Zhi-hua Li, Qiu-yun Xiong, Jian-hong Tu, Yu Gong, Wei Qiu, Hui-qin Zhang, Wen-shong Wei, Yi-Feng Hou, Wei-qi Cui

Original Paper

Association of tumor-associated fibroblasts with progression of hepatocellular carcinoma

Xiao-Yu Yang, Dong Zhang, Qi-Fei Zou, Fei Fan, Feng Shen

Original Paper

The role of systemic inflammatory and nutritional blood-borne markers in predicting response to neoadjuvant chemotherapy and survival in oesophagogastric cancer

Fergus Noble, James Hopkins, Nathan Curtis, Jamie J. Kelly, Ian S. Bailey, James P. Byrne, Adrian C. Bateman, Andrew R. Bateman, Timothy J. Underwood

Original Paper

Association between human papillomavirus and endometrial adenocarcinoma

Nimet Karadayi, Melin Gecer, Sibel Kayahan, Elif Yamuc, Nilufer Kandemir Onak, Taner Korkmaz, Dilek Yavuzer

Original Paper

The influence of genetic polymorphisms in MDR1 gene on breast cancer risk factors in Chinese

Yunhe Jia, Wenjing Tian, Shuai Sun, Peng Han, Weinan Xue, Mingqi Li, Yanlong Liu, Shixiong Jiang, Binbin Cui

Original Paper

High expression of PRDM14 correlates with cell differentiation and is a novel prognostic marker in resected non-small cell lung cancer

Tiehong Zhang, Long Meng, Wei Dong, Hongchang Shen, Shuming Zhang, Qi Liu, Jiajun Du

Original Paper

Smad3 is the key to transforming growth factor-β1-induced osteoclast differentiation in giant cell tumor of bone

Zhiyuan Lou, Yi Yang, Tingting Ren, Shun Tang, Xianbo Peng, Qunshan Lu, Yifeng Sun, Wei Guo

Original Paper

High expression of Transient potential receptor C6 correlated with poor prognosis in patients with esophageal squamous cell carcinoma

Shui-Shen Zhang, Jing Wen, Fu Yang, Xiao-Li Cai, Hong Yang, Kong-Jia Luo, Qian Wen Liu, Rong-Gui Hu, Xuan Xie, Qing-Yuan Huang, Jun Ying Chen, Jian Hua Fu, Yi Hu

Original Paper

Arrhythmias during and after zoledronic acid infusion patients with bone metastasis

Ozan Yazici, Sercan Aksoy, Ozgul Ucar, Nuriye Ozdemir, Mevlut Demir, Mehmet Ali Nahit Sendur, Zafer Arik, Sebnem Yaman, Tulay Eren, Dogan Uncu, Nurullah Zengin

Open Access Original Paper

Prognostic factors and long-term outcome of autologous haematopoietic stem cell transplantation following a uniform-modified BEAM-conditioning regimen for patients with refractory or relapsed Hodgkin lymphoma: a single-center experience

Anna Czyz, Anna Lojko-Dankowska, Dominik Dytfeld, Adam Nowicki, Lidia Gil, Magdalena Matuszak, Maria Kozlowska-Skrzypczak, Maciej Kazmierczak, Ewa Bembnista, Mieczysław Komarnicki

Original Paper

Expression of synuclein gamma indicates poor prognosis of triple-negative breast cancer

Kejin Wu, Shuo Huang, Mingjie Zhu, Yunshu Lu, Jian Chen, Yongkun Wang, Qing Lin, Wei Shen, Shenglai Zhang, Jian Zhu, Y. Eric Shi, Ziyi Weng

Original Paper

Immunohistochemical expression and mutation study of Prohibitin gene in Indian female breast cancer cases

Mohammad Zeeshan Najm, Shuaib Zaidi, Waseem Ahmad Siddiqui, Syed Akhtar Husain

Original Paper

Outcomes of locally advanced breast cancer patients with ≥10 positive axillary lymph nodes

Emre Koca, Taha Y. Kuzan, Omer Dizdar, Taner Babacan, Ilyas Sahin, Erhan Ararat, Kadri Altundag

Original Paper

RNA interference targeting adrenomedullin induces apoptosis and reduces the growth of human bladder urothelial cell carcinoma

Ai-guang Liu, Xi-zhong Zhang, Fen-bao Li, Yong-li Zhao, Ying-chang Guo, Rui-min Yang

Original Paper

PTPN12 inhibits oral squamous epithelial carcinoma cell proliferation and invasion and can be used as a prognostic marker

Zhe Su, Hua Tian, Hong-quan Song, Rui Zhang, An-mei Deng, Hong-wen Liu

Original Paper

Decreased expression of DUSP4 is associated with liver and lung metastases in colorectal cancer

Susumu Saigusa, Yasuhiro Inoue, Koji Tanaka, Yuji Toiyama, Yoshinaga Okugawa, Tadanobu Shimura, Junichiro Hiro, Keiichi Uchida, Yasuhiko Mohri, Masato Kusunoki

Original Paper

Effects of legumain as a potential prognostic factor on gastric cancers

Na Li, Qiaoling Liu, Qi Su, Chongyang Wei, Bin Lan, Jianyong Wang, Guoqing Bao, Fei Yan, Ying Yu, Baowei Peng, Ju Qiu, Xiangming Yan, Sheng Zhang, Fang Guo

Original Paper

The expression of hepatoma-derived growth factor in primary central nervous system lymphoma and its correlation with angiogenesis, proliferation and clinical outcome

San-Zhong Li, Yong-Bo Zhao, Wei-Dong Cao, Yan Qu, Peng Luo, Hai-Ning Zhen, Xiao-Yan Chen, Zhi-Feng Yan, Zhou Fei

Original Paper

Clinical characteristics and outcomes of patients with small cell lung cancer detected by CT screening

Toshirou Fukushima, Kazunari Tateishi, Hiroshi Yamamoto, Masayuki Hanaoka, Keishi Kubo, Tomonobu Koizumi

Original Paper

Prognostic factors for teenage and adult patients with high-grade osteosarcoma: an analysis of 240 patients

Ayse Durnali, Necati Alkis, Sengul Cangur, Fisun Ardic Yukruk, Ali Inal, Saadet Tokluoglu, Mehmet Metin Seker, Oznur Bal, Tulay Akman, Mevlude Inanc, Abdurrahman Isikdogan, Ayse Demirci, Kaan Helvaci, Berna Oksuzoglu

Original Paper

Discoidin domain receptor 1 is associated with poor prognosis of non-small cell lung cancer and promotes cell invasion via epithelial-to-mesenchymal transition

Liyun Miao, Suhua Zhu, Yongsheng Wang, Yan Li, Jingjing Ding, Jinghong Dai, Hourong Cai, Deping Zhang, Yong Song

Original Paper

Up-regulation of Ago2 expression in gastric carcinoma

Jin Zhang, Xiang-shan Fan, Cai-xia Wang, Biao Liu, Qin Li, Xiao-jun Zhou

Original Paper

Associations between UGT1A1*6/*28 polymorphisms and irinotecan-induced severe toxicity in Chinese gastric or esophageal cancer patients

Jing Gao, Jun Zhou, Yanyan Li, Zhi Peng, Yilin Li, Xicheng Wang, Lin Shen

Original Paper

Upregulated ZO-1 correlates with favorable survival of gastrointestinal stromal tumor

Huijun Zhu, Juying Lu, Xudong Wang, Huilin Zhang, Xiaojun Tang, Jin Zhu, Yuan Mao

Original Paper

Heparanase expression correlates with poor survival in oral mucosal melanoma

Xin Wang, Weiwei Wen, Heming Wu, Yi Chen, Guoxin Ren, Wei Guo

Original Paper

Bone metastasis from breast cancer involves elevated IL-11 expression and the gp130/STAT3 pathway

Li Ren, Xia Wang, Zuoliang Dong, Jun Liu, Shiwu Zhang

Original Paper

Combined therapy in untreated patients improves outcome in Nasal NK/T lymphoma: results of a clinical trial

Agustin Avilés, Natividad Neri, Raúl Fernández, Judith Huerta-Guzmán, Maria-Jesus Nambo

Original Paper

Factors influencing survival in metastatic synovial sarcoma: importance of patterns of metastases and the first-line chemotherapy regimen

Samer Salah, Sameer Yaser, Ahmed Salem, Abdellatif Al Mousa, Areej Abu Sheikha, Iyad Sultan

Original Paper

Age-specific effect of gender on upper tract urothelial carcinoma outcomes

Jian-Ye Liu, Yong-Hong Li, Zhi-Ling Zhang, Yun-Lin Ye, Zhou-Wei Liu, Kai Yao, Pei Dong, Sheng-Jie Guo, Li-Juan Jiang, Ming-Zhu Zhong, Wei Chen, Hui Han, Zi-Ke Qin, Fang-Jian Zhou

Original Paper

Potential clinical significance of ERβ ON promoter methylation in sporadic breast cancer

Ana Božović, Milan Markićević, Bogomir Dimitrijević, Snežana Jovanović Ćupić, Milena Krajnović, Silvana Lukić, Vesna Mandušić

Original Paper

Association between single genetic polymorphisms of MDR1 gene and gastric cancer susceptibility in Chinese

Wen Qiao, Tao Wang, Li Zhang, Qing Tang, Dan Wang, Hongkun Sun

Original Paper

Down-regulation of ribosomal protein L22 in non-small cell lung cancer

Mingxia Yang, Haibo Sun, Hong Wang, Shijiang Zhang, Xiaowei Yu, Lei Zhang

Original Paper

The type of patients who would benefit from anti-androgen withdrawal therapy: could it be performed safely for aggressive prostate cancer?

Kazuhiro Matsumoto, Nobuyuki Tanaka, Nozomi Hayakawa, Taisuke Ezaki, Kenjiro Suzuki, Takahiro Maeda, Akiharu Ninomiya, So Nakamura

Original Paper

Clinical value of mesothelin in pleural effusions versus histology by medical thoracoscopy: brief report

Pier Aldo Canessa, Paola Ferro, Carmen Manta, Massimiliano Sivori, Maria Cristiana Franceschini, Franco Fedeli, Silvio Roncella

Original Paper

Detection of perioperative cancer antigen 72-4 in gastric juice pre- and post-distal gastrectomy and its significances

Lei Huang, Aman Xu, Tuanjie Li, Wenxiu Han, Shanshan Wu, Yangyi Wang

Original Paper

Sorafenib versus capecitabine in the management of advanced hepatocellular carcinoma

Omar Abdel-Rahman, Manal Abdel-Wahab, Mohammed Shaker, Sherif Abdel-Wahab, Mohammed Elbassiony, Mahmoud Ellithy

Original Paper

Comparison between zoledronic acid and clodronate in the treatment of prostate cancer patients with bone metastases

Feng Wang, Wei Chen, Hongde Chen, Licai Mo, Haiyong Jin, Zhixian Yu, Chengdi Li, Qing Liu, Feifei Duan, Zhiliang Weng

Original Paper

Genetic analysis of ADIPOQ variants and gastric cancer risk: a hospital-based case–control study in China

Lei Ye, Zuo-Yang Zhang, Wei-Dong Du, Marion E. Schneider, Yue Qiu, Yuan Zhou, Fu-Sheng Zhou, Xian-Bo Zuo, Gang Chen, Xue-Ling Ma, Hong-Zhen Xia, Song Xu, Ji-Feng Wu, Hong-Yuan Xu, Xue-Jun Zhang

Original Paper

Comparison of two different adjuvant treatment modalities for pN3 gastric cancer patients after D2 lymph node dissection: can we avoid radiotherapy in a subgroup of patients?

Leyla Kilic, Cetin Ordu, Meltem Ekenel, Ibrahim Yildiz, Serkan Keskin, Fatma Sen, Zeynep Gural, Oktar Asoglu, Ahmet Kizir, Faruk Aykan

Original Paper

Soluble ICAM-1 levels in small-cell lung cancer: prognostic value for survival and predictive significance for response during chemotherapy

Elias A. Kotteas, Ioannis Gkiozos, Sofia Tsagkouli, Antonios Bastas, Ioannis Ntanos, Muhammad W. Saif, Konstantinos N. Syrigos

Original Paper

Colorectal carcinoma-derived fibroblasts modulate natural killer cell phenotype and antitumor cytotoxicity

Tuanjie Li, Shuhong Yi, Wei Liu, Changchang Jia, Guoying Wang, Xuefeng Hua, Yan Tai, Qi Zhang, Guihua Chen

Original Paper

Feasibility and efficacy of combined cisplatin plus irinotecan chemotherapy for gastroenteropancreatic neuroendocrine carcinomas

Z. H. Lu, J. Li, M. Lu, X. T. Zhang, J. Li, J. Zhou, X. C. Wang, J. F. Gong, J. Gao, Y. Li, L. Shen

Original Paper

Haplotype structures and functional polymorphic variants of the drug target enzyme aromatase (CYP19A1) in South Indian population

Gurusamy Umamaheswaran, Steven Aibor Dkhar, Sekar Kalaivani, Raj Anjana, Mohan Revathy, Mohammad Jaharamma, Kulumani Mahadevan Lakshmi Shree, Dharanipragada Kadambari, Chandrasekaran Adithan

Original Paper

Role of KAI1/CD82 polymorphisms in colon cancer risk in Han Chinese population

Zhen-Bin Ma, Kun Li, Jian Wang, Guang-Hong Guo

Original Paper

Up-regulation of HOTAIR long non-coding RNA in human gastric adenocarcinoma tissues

Mohammadreza Hajjari, Mehrdad Behmanesh, Majid Sadeghizadeh, Mehdi Zeinoddini

Original Paper

Age–period–cohort effect on female breast cancer mortality in Southern Spain

Ricardo Ocaña-Riola, José María Mayoral-Cortés, Eulalia Navarro-Moreno

Original Paper

Epidermal growth factor, its receptor and transforming growth factor-β1 in the diagnosis of HCV-induced hepatocellular carcinoma

Fatma Shehata, Nihad Abdel Monem, Mohamed Sakr, Samar Kasem, Mahmoud Balbaa

Original Paper

Androgen receptor in human prostate cancer-associated fibroblasts promotes prostate cancer epithelial cell growth and invasion

Shengqiang Yu, Shujie Xia, Diandong Yang, Ke Wang, Shuyuan Yeh, Zhenli Gao, Chawnshang Chang

Original Paper

Phase2 study of bevacizumab with carboplatin–paclitaxel for non-small cell lung cancer with malignant pleural effusion

Motohiro Tamiya, Akihiro Tamiya, Tadahiro Yamadori, Keiko Nakao, Kazuhiro Asami, Tomomi Yasue, Tomoyuki Otsuka, Takayuki Shiroyama, Naoko Morishita, Hidekazu Suzuki, Norio Okamoto, Kyoichi Okishio, Tomoya Kawaguchi, Shinji Atagi, Ichiro Kawase, Tomonori Hirashima

Original Paper

Identification of a 5-gene signature for clinical and prognostic prediction in gastric cancer patients upon microarray data

Zhigang Wang, Zhi Yan, Bicheng Zhang, Zhiguo Rao, Yafei Zhang, Jian Liu, Lifang Yu, Yong Zhao, Bo Yang, Tingting Wu, Jianfei Gao

Open Access Original Paper

Effect of increased body mass index (BMI) on time to tumour progression (TTP) in unresectable metastatic colorectal cancer (mCRC) patients treated with bevacizumab-based therapy

N. Faruk Aykan, Ibrahim Yildiz, Fatma Sen, Leyla Kilic, Serkan Keskin, Rumeysa Ciftci, Senem Karabulut, Burak Sakar, Rian Disci

Original Paper

Upregulation of microRNA-203 is associated with advanced tumor progression and poor prognosis in epithelial ovarian cancer

Shaosheng Wang, Xiaohong Zhao, Jie Wang, Yingmei Wen, LinJing Zhang, Dezhu Wang, Huili Chen, Qiuxia Chen, Wei Xiang

Original Paper

p14ARF methylation is a common event in the pathogenesis and progression of myxoid and pleomorphic liposarcoma

Radoslav Davidović, Jelena Sopta, Vesna Mandušić, Milena Krajnović, Maja Stanojević, Goran Tulić, Bogomir Dimitrijević

Original Paper

Association analysis between MDR1 genetic variant and breast cancer risk factors in Chinese Han population

Yi Hu, Jingliang Wang, Haitao Tao, Huan Wang, Xin Zhang, Yao Cheng, Ruixin Li

Original Paper

CIP2A expression and prognostic role in patients with esophageal adenocarcinoma

Tuomo Rantanen, Tuuli Kauttu, Jonne Åkerla, Teemu Honkanen, Leena Krogerus, Jarmo Salo, Timo Paavonen, Niku Oksala

Original Paper

Pattern of clinically relevant mutations in consecutive series of Russian colorectal cancer patients

Grigoriy A. Yanus, Anna V. Belyaeva, Alexandr O. Ivantsov, Ekatherina Sh. Kuligina, Evgeny N. Suspitsin, Natalia V. Mitiushkina, Svetlana N. Aleksakhina, Aglaya G. Iyevleva, Olga A. Zaitseva, Olga S. Yatsuk, Tatiana V. Gorodnova, Tatiana N. Strelkova, Sofia A. Efremova, Alla Yu. Lepenchuk, Altn N. Ochir-Garyaev, Moisey B. Paneyah, Dmitriy E. Matsko, Alexandr V. Togo, Evgeny N. Imyanitov

Review Article

Role of BAX for outcome prediction in gastrointestinal malignancies

Filippo Pietrantonio, Pamela Biondani, Elisa Ciurlia, Giuseppe Fanetti, Anna Tessari, Gaia Bertarelli, Ilaria Bossi, Valeria Musella, Flavia Melotti, Maria Di Bartolomeo, Francesca Valvo, Alessandro Pellegrinelli, Massimo Milione, Federica Perrone, Filippo de Braud

Review Article

Therapy-related acute promyelocytic leukemia: a systematic review

Armin Rashidi, Stephen I. Fisher

Review Article

Triple-negative breast cancer: new perspectives for novel therapies

Yashin A. Mahamodhossen, Wei Liu, Zhou Rong-Rong

Review Article

Identifying oncological emergencies

Achuta K. Guddati, Nilay Kumar, Ankur Segon, Parijat S. Joy, Creticus P. Marak, Gagan Kumar

Review Article

The role of microRNAs in lung cancer progression

Wen-Cheng Zhang, Jinbo Liu, Xiangying Xu, Guangshun Wang

Short Communication

Tumor lysis syndrome and malignant melanoma

Meir Mouallem, Noa Zemer-Wassercug, Eitan Kugler, Nadav Sahar, Ronnie Shapira-Frommer, Ginette Schiby

Short Communication

Phase II study of weekly PM00104 (ZALYPSIS®) in patients with pretreated advanced/metastatic endometrial or cervical cancer

Lainie P. Martin, Carolyn Krasner, Teresa Rutledge, Manuel Luque Ibañes, Eva M. Fernández-García, Carmen Kahatt, Mariano Siguero Gómez, Scott McMeekin

Short Communication

Vandetanib combined with a p38 MAPK inhibitor synergistically reduces glioblastoma cell survival

Linda Sooman, Johan Lennartsson, Joachim Gullbo, Michael Bergqvist, Georgios Tsakonas, Fredrik Johansson, Per-Henrik Edqvist, Fredrik Pontén, Archita Jaiswal, Sanjay Navani, Irina Alafuzoff, Svetlana Popova, Erik Blomquist, Simon Ekman

Short Communication

Evidence for angiogenesis-independent contribution of VEGFR1 (FLT1) in gastric cancer recurrence

Evgeny N. Suspitsin, Aniruddh Kashyap, Kseniya V. Shelekhova, Anna P. Sokolenko, Ekatherina Sh. Kuligina, Aglaya G. Iyevleva, Alexandr V. Kornilov, Volker Ehemann, Grigoriy A. Yanus, Svetlana N. Aleksakhina, Elena V. Preobrazhenskaya, Olga A. Zaitseva, Olga S. Yatsuk, Valeriy F. Klimashevsky, Alexandr V. Togo, Evgeny N. Imyanitov

Short Communication

Correlation of EGFR mutation and predominant histologic subtype according to the new lung adenocarcinoma classification in Chinese patients

Zhengbo Song, Huineng Zhu, Zhenying Guo, Wei Wu, Wenyong Sun, Yiping Zhang

Short Communication

Prognostic value of the Glasgow Prognostic Score in metastatic colorectal cancer in the era of anti-EGFR therapies

Johann Dréanic, Marianne Maillet, Marion Dhooge, Olivier Mir, Catherine Brezault, François Goldwasser, Stanislas Chaussade, Romain Coriat

Short Communication

Incidences of diabetes and prediabetes among female adult breast cancer patients after systemic treatment

Guang-yan Ji, Liang-bin Jin, Rui-jue Wang, Yang Bai, Zi-xiang Yao, Lin-jie Lu, Jian-bo Huang, Sheng-chun Liu, Hong-yuan Li, Zi-wei Wang, Guo-sheng Ren, Kai-nan Wu, Ling-quan Kong

Letter to the Editor

Enhanced SOX10 and KIT expression in cutaneous melanoma

Lars Rönnstrand, Bengt Phung

Letter to the Editor

The basic helix-loop-helix (bHLH) proteins in breast cancer progression

Nuzhat N. Kabir, Lars Rönnstrand, Julhash U. Kazi

Adjuvante Immuntherapie verlängert Leben bei RCC

25.04.2024 Nierenkarzinom Nachrichten

Nun gibt es auch Resultate zum Gesamtüberleben: Eine adjuvante Pembrolizumab-Therapie konnte in einer Phase-3-Studie das Leben von Menschen mit Nierenzellkarzinom deutlich verlängern. Die Sterberate war im Vergleich zu Placebo um 38% geringer.

Alectinib verbessert krankheitsfreies Überleben bei ALK-positivem NSCLC

25.04.2024 NSCLC Nachrichten

Das Risiko für Rezidiv oder Tod von Patienten und Patientinnen mit reseziertem ALK-positivem NSCLC ist unter einer adjuvanten Therapie mit dem Tyrosinkinase-Inhibitor Alectinib signifikant geringer als unter platinbasierter Chemotherapie.

Bei Senioren mit Prostatakarzinom auf Anämie achten!

24.04.2024 DGIM 2024 Nachrichten

Patienten, die zur Behandlung ihres Prostatakarzinoms eine Androgendeprivationstherapie erhalten, entwickeln nicht selten eine Anämie. Wer ältere Patienten internistisch mitbetreut, sollte auf diese Nebenwirkung achten.

ICI-Therapie in der Schwangerschaft wird gut toleriert

Müssen sich Schwangere einer Krebstherapie unterziehen, rufen Immuncheckpointinhibitoren offenbar nicht mehr unerwünschte Wirkungen hervor als andere Mittel gegen Krebs.

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