Susceptibility difference weighted imaging in vertical-field MRI

To realize susceptibility-weighted imaging in vertical-field magnetic resonance imaging (MRI), we developed an image-processing method called “susceptibility difference weighted imaging” (SDWI). In SDWI, contrasts are enhanced using a susceptibility map calculated by using a weighted least-square algorithm with a small iteration number. Experiments were performed on human volunteers to compare image contrast obtained from the conventional method (SWI) and SDWI. In horizontal-field MRI, SDWI results show that veins and deep-gray-matter nuclei were visualized as well as those with SWI. In vertical-field MRI, SDWI visualized veins and deep-gray-matter nuclei without severe streaking artifacts, while SWI did not. In our experiments, the time taken to calculate the susceptibility map in SDWI was less than 10 s. The results indicate that susceptibility-weighted imaging is feasible in vertical-field MRI using SDWI.