Erschienen in:
01.08.2012
The Clinical Relevance of the Clopidogrel–Proton Pump Inhibitor Interaction
verfasst von:
Atif Mohammad, Emmanouil S. Brilakis, Rick A. Weideman, Bertis B. Little, Subhash Banerjee
Erschienen in:
Journal of Cardiovascular Translational Research
|
Ausgabe 4/2012
Einloggen, um Zugang zu erhalten
Abstract
Proton pump inhibitors are often prescribed concomitantly with clopidogrel and aspirin to patients post-percutaneous coronary interventions and/or an acute coronary syndrome to mitigate the risk of potential gastrointestinal bleeding, associated primarily with clopidogrel use. Over the last several years, there have been data both supporting and refuting a clopidogrel–proton pump inhibitor interaction. This review critically considers the current evidence and provides practical recommendations to healthcare providers.