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28.11.2019 | Review and Perspectives

The clinico-pathological spectrum of primary cutaneous lymphoma other than mycosis fungoides/Sezary syndrome

verfasst von: Ilske Oschlies, Rebecca L. King, Snjezana Dotlic, Santiago Montes-Moreno, Maurilio Ponzoni, Alexandra Traverse-Glehen, Maria Calaminici, Judith A. Ferry, German Ott, John R Goodlad

Erschienen in: Virchows Archiv | Ausgabe 5/2020

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Abstract

The major aim of Session 1 of the 2018 European Association of Hematopathology/Society for Hematopathology Workshop was to collect examples of cutaneous lymphomas, excluding mycosis fungoides/Sezary syndrome, as defined in the current WHO classification of tumours of the haemetopoietic and lymphoid tissues. Overall 42 cases were submitted. These were considered in four main categories: primary cutaneous B cell lymphomas (12 cases), primary cutaneous T cell lymphomas/lymphoproliferations with CD8+/cytotoxic phenotype (12 cases), primary cutaneous CD30-positive lymphoproliferative disorders (15 cases) and primary cutaneous T cell lymphomas/leukaemias with CD4+ phenotype (4 cases). Using these cases as examples, we were able to present the full spectrum of cutaneous lymphoproliferations (excluding mycosis fungoides/Sezary syndrome), including examples of rare, provisional and new entities as listed in the 2017 update of the WHO classification. The findings are summarized in this report with emphasis on differential diagnostic considerations and the importance of clinico-pathological correlation for final subtyping. In presenting these findings we hope to raise awareness of this enigmatic group of neoplasms and to further our understanding of these rare disease entities.

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Titel: The clinico-pathological spectrum of primary cutaneous lymphoma other than mycosis fungoides/Sezary syndrome
verfasst von: Ilske Oschlies
Rebecca L. King
Snjezana Dotlic
Santiago Montes-Moreno
Maurilio Ponzoni
Alexandra Traverse-Glehen
Maria Calaminici
Judith A. Ferry
German Ott
John R Goodlad
Publikationsdatum: 28.11.2019
Verlag: Springer Berlin Heidelberg
Erschienen in: Virchows Archiv / Ausgabe 5/2020
Print ISSN: 0945-6317
Elektronische ISSN: 1432-2307
DOI: https://doi.org/10.1007/s00428-019-02713-7

Springer Medizin

The clinico-pathological spectrum of primary cutaneous lymphoma other than mycosis fungoides/Sezary syndrome

Abstract

Neu im Fachgebiet Pathologie

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie

Springer Medizin

Abstract

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