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Sleep and Breathing

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21.08.2019 | Sleep Breathing Physiology and Disorders • Original Article

The distinct roles of OSA and depression severity in day- and night-time symptomatology in OSA patients: a pilot study

verfasst von: Mariza van Wyk, Siobhan McCreesh-Toselli, Stevie Williams, Irshaad O Ebrahim

Erschienen in: Sleep and Breathing | Ausgabe 3/2020

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Abstract

Purpose

Obstructive sleep apnoea (OSA) is a common sleep disorder and is associated with a number of comorbid conditions, including the frequent occurrence of depression. Notably, there is a considerate overlap in day- as well as night-time symptomatology in depression and OSA. In light of this, we aimed to disentangle the distinct effects of OSA and depression severity on day- and night-time symptomatology.

Methods

This pilot study (N = 320) utilized a retrospective chart review design and included both males and females who met the minimum diagnostic criteria for OSA. Daytime symptoms (sleepiness and fatigue) were assessed via questionnaires, while night-time symptoms were measured via polysomnography.

Results

Main findings include the following: (a) no association between OSA and depression severity, (b) depression severity significantly predicted increased sleepiness and fatigue (c) OSA severity significantly predicted increased stage 2 non-rapid eye movement sleep percentage, (d) OSA significantly predicted decreased stage 3 non-rapid eye movement sleep percentage and rapid eye movement sleep percentage. Overall, depression severity exerts the strongest influence on daytime symptomatology, while OSA severity exerts the strongest influence on night-time symptomatology. Moreover, with the exception of sleepiness, no overlap between day- and night-time findings was detected.

Conclusion

OSA and depression, although comorbid, possibly constitute distinct disease processes in this population group. Consequently, solely devising treatment targeting a reduction in apnoea-hypopnoea index might not be sufficient in alleviating debilitating daytime symptoms in treatment-seeking individuals.

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Titel: The distinct roles of OSA and depression severity in day- and night-time symptomatology in OSA patients: a pilot study
verfasst von: Mariza van Wyk
Siobhan McCreesh-Toselli
Stevie Williams
Irshaad O Ebrahim
Publikationsdatum: 21.08.2019
Verlag: Springer International Publishing
Erschienen in: Sleep and Breathing / Ausgabe 3/2020
Print ISSN: 1520-9512
Elektronische ISSN: 1522-1709
DOI: https://doi.org/10.1007/s11325-019-01924-1

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The distinct roles of OSA and depression severity in day- and night-time symptomatology in OSA patients: a pilot study