Erschienen in:
22.03.2016
The role of pharmacotherapy in the prevention of sudden cardiac death in patients with heart failure
verfasst von:
Phillip A. Weeks, Adam Sieg, Jennifer Ann Gass, Indranee Rajapreyar
Erschienen in:
Heart Failure Reviews
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Ausgabe 4/2016
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Abstract
Sudden cardiac death remains a significant threat to the survival of patients with heart failure. Long-term cardiac remodeling predisposes these patients to develop malignant ventricular arrhythmias. Permanent implantable and temporary external defibrillators remain a mainstay for the prevention of sudden cardiac death in this population. For decades, researchers have attempted to identify reliable drug therapies to avoid such arrhythmias; however, to date, success has been inconsistent. This review aims to explore the evidence defining the role of drug therapies for direct and indirect suppression of arrhythmias that may cause sudden cardiac death in patients with heart failure.