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Erschienen in: Surgical Endoscopy 6/2018

03.11.2017

The use of high definition colonoscopy versus standard definition: does it affect polyp detection rate?

verfasst von: John Richardson, Anthony Thaventhiran, Hugh Mackenzie, Benjamin Stubbs

Erschienen in: Surgical Endoscopy | Ausgabe 6/2018

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Abstract

Background

Polyp detection rate (PDR) during lower gastrointestinal endoscopy (LGIE) is of clinical importance. Detecting adenomatous polyps early in the adenoma–carcinoma sequence can halt disease progression, enabling treatment at a favourable stage. High definition colonoscopy (HDC) has been used in our hospital alongside standard definition equipment since 2011. We aim to determine what affect the use of HDC has on PDR.

Methods

Post-hoc analysis of a prospectively maintained database on all patients undergoing LGIE was performed (01/01/2012–31/12/2015), n = 15,448. Analysis tested the primary outcome of HD’s effect on PDR across LGIE and secondary outcome stratified this by endoscopist group (Physician (PE), Surgeon (SE) and Nurse Endoscopist (NE)).

Results

Of 15,448 patients, 1353 underwent HDC. Unmatched analysis showed PDR increased by 5.3% in this group (p < 0.001). Matched analysis considered 2288 patients from the total cohort (1144 HDC) and showed an increase of 1% in PDR with HDC (p = 0.578). Further unmatched analysis stratified by endoscopist groups showed a PDR increase of 1.8% (p = 0.375), 5.4% (p = 0.008) and 4.6% (p = 0.021) by PE, SE and NE respectively. Matched analysis demonstrated an increase of 1% (p = 0.734) and 1.5% (p = 0.701) amongst PE and NE, with a decrease of 0.6% (p = 0.883) by SE.

Conclusion

The introduction of HDC increased PDR across all LGIE in our hospital, though this was not clinically significant. This marginal benefit was present across all endoscopist groups with no group benefiting over another in matched analysis.
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Literatur
1.
Zurück zum Zitat Marks G (1979) Guidelines for use of flexible fiberoptic colonoscopy in management of patients with colorectal neoplasia. Dis Colon Rectum 22(5):302–305CrossRefPubMed Marks G (1979) Guidelines for use of flexible fiberoptic colonoscopy in management of patients with colorectal neoplasia. Dis Colon Rectum 22(5):302–305CrossRefPubMed
2.
Zurück zum Zitat Wolff WI (1989) Colonoscopy: history and development. Am J Gastroenterol 84(9):1017–1025PubMed Wolff WI (1989) Colonoscopy: history and development. Am J Gastroenterol 84(9):1017–1025PubMed
4.
Zurück zum Zitat Morson BC (1974) Evolution of cancer of the colon and rectum. Cancer 34(suppl3):845–849CrossRef Morson BC (1974) Evolution of cancer of the colon and rectum. Cancer 34(suppl3):845–849CrossRef
5.
Zurück zum Zitat Muto T, Bussey HJ, Morson BC (1975) The evolution of cancer of the colon and rectum. Cancer 36(6):2251–2270CrossRefPubMed Muto T, Bussey HJ, Morson BC (1975) The evolution of cancer of the colon and rectum. Cancer 36(6):2251–2270CrossRefPubMed
6.
Zurück zum Zitat Stryker SJ, Wolff BG, Culp CE, Libbe SD, Ilstrup DM, MacCarty RL (1987) Natural history of untreated colonic polyps. Gastroenterology 93(5):1009–1013CrossRefPubMed Stryker SJ, Wolff BG, Culp CE, Libbe SD, Ilstrup DM, MacCarty RL (1987) Natural history of untreated colonic polyps. Gastroenterology 93(5):1009–1013CrossRefPubMed
7.
Zurück zum Zitat Haggitt RC, Reid BJ (1986) Hereditary gastrointestinal polyposis syndromes. Am J Surg Pathol 10(12):871–887CrossRefPubMed Haggitt RC, Reid BJ (1986) Hereditary gastrointestinal polyposis syndromes. Am J Surg Pathol 10(12):871–887CrossRefPubMed
8.
Zurück zum Zitat Cannon-Albright LA, Skolnick MH, Bishop DT, Lee RG, Burt RW (1988) Common inheritance of susceptibility to colonic adenomatous polyps and associated colorectal cancers. N Engl J Med 319(9):533–537CrossRefPubMed Cannon-Albright LA, Skolnick MH, Bishop DT, Lee RG, Burt RW (1988) Common inheritance of susceptibility to colonic adenomatous polyps and associated colorectal cancers. N Engl J Med 319(9):533–537CrossRefPubMed
9.
Zurück zum Zitat Atkin WS, Cook CF, Cuzick J, Edwards R, Northover JM, Wardle J et al (2002) Single flexible sigmoidoscopy screening to prevent colorectal cancer: baseline findings of a UK multicentre randomised trial. Lancet 359(9314):1291 – 300CrossRefPubMed Atkin WS, Cook CF, Cuzick J, Edwards R, Northover JM, Wardle J et al (2002) Single flexible sigmoidoscopy screening to prevent colorectal cancer: baseline findings of a UK multicentre randomised trial. Lancet 359(9314):1291 – 300CrossRefPubMed
10.
Zurück zum Zitat West NJ, Poullis AP, Leicester RJ (2008) The NHS Bowel Cancer Screening Programme: a realistic approach with additional benefits. Colorectal Dis 10(7):708–714CrossRefPubMed West NJ, Poullis AP, Leicester RJ (2008) The NHS Bowel Cancer Screening Programme: a realistic approach with additional benefits. Colorectal Dis 10(7):708–714CrossRefPubMed
11.
Zurück zum Zitat Atkin WS, Edwards R, Kralj-Hans I, Wooldrage K, Hart AR, Northover JM et al (2010) Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trial. Lancet 375(9726):1624–1633CrossRefPubMed Atkin WS, Edwards R, Kralj-Hans I, Wooldrage K, Hart AR, Northover JM et al (2010) Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trial. Lancet 375(9726):1624–1633CrossRefPubMed
12.
Zurück zum Zitat Logan RF, Patnick J, Nickerson C, Coleman L, Rutter MD, von Wagner C et al (2012) Outcomes of the bowel cancer screening programme (BCSP) in England after the first 1 million tests. Gut 61(10):1439–1446CrossRefPubMed Logan RF, Patnick J, Nickerson C, Coleman L, Rutter MD, von Wagner C et al (2012) Outcomes of the bowel cancer screening programme (BCSP) in England after the first 1 million tests. Gut 61(10):1439–1446CrossRefPubMed
13.
Zurück zum Zitat McGregor LM, Bonello B, Kerrison RS, Nickerson C, Baio G, Berkman L et al (2015) Uptake of Bowel Scope (Flexible Sigmoidoscopy) Screening in the English National Programme: the first 14 months. J Med Screen 23:77CrossRefPubMed McGregor LM, Bonello B, Kerrison RS, Nickerson C, Baio G, Berkman L et al (2015) Uptake of Bowel Scope (Flexible Sigmoidoscopy) Screening in the English National Programme: the first 14 months. J Med Screen 23:77CrossRefPubMed
14.
Zurück zum Zitat Rutter MD, Chattree A, Barbour JA, Thomas-Gibson S, Bhandari P, Saunders BP et al (2015) British Society of Gastroenterology/Association of Coloproctologists of Great Britain and Ireland guidelines for the management of large non-pedunculated colorectal polyps. Gut 64(12):1847–1873CrossRefPubMedPubMedCentral Rutter MD, Chattree A, Barbour JA, Thomas-Gibson S, Bhandari P, Saunders BP et al (2015) British Society of Gastroenterology/Association of Coloproctologists of Great Britain and Ireland guidelines for the management of large non-pedunculated colorectal polyps. Gut 64(12):1847–1873CrossRefPubMedPubMedCentral
15.
Zurück zum Zitat Francis DL, Rodriguez-Correa DT, Buchner A, Harewood GC, Wallace M (2011) Application of a conversion factor to estimate the adenoma detection rate from the polyp detection rate. Gastrointest Endosc 73(3):493–497CrossRefPubMed Francis DL, Rodriguez-Correa DT, Buchner A, Harewood GC, Wallace M (2011) Application of a conversion factor to estimate the adenoma detection rate from the polyp detection rate. Gastrointest Endosc 73(3):493–497CrossRefPubMed
16.
Zurück zum Zitat Patel NC, Islam RS, Wu Q, Gurudu SR, Ramirez FC, Crowell MD et al (2013) Measurement of polypectomy rate by using administrative claims data with validation against the adenoma detection rate. Gastrointest Endosc 77(3):390–394CrossRefPubMed Patel NC, Islam RS, Wu Q, Gurudu SR, Ramirez FC, Crowell MD et al (2013) Measurement of polypectomy rate by using administrative claims data with validation against the adenoma detection rate. Gastrointest Endosc 77(3):390–394CrossRefPubMed
17.
Zurück zum Zitat Gohel TD, Burke CA, Lankaala P, Podugu A, Kiran RP, Thota PN et al (2014) Polypectomy rate: a surrogate for adenoma detection rate varies by colon segment, gender, and endoscopist. Clin Gastroenterol Hepatol 12(7):1137–1142CrossRefPubMed Gohel TD, Burke CA, Lankaala P, Podugu A, Kiran RP, Thota PN et al (2014) Polypectomy rate: a surrogate for adenoma detection rate varies by colon segment, gender, and endoscopist. Clin Gastroenterol Hepatol 12(7):1137–1142CrossRefPubMed
18.
Zurück zum Zitat Atkin W, Rogers P, Cardwell C, Cook C, Cuzick J, Wardle J et al (2004) Wide variation in adenoma detection rates at screening flexible sigmoidoscopy. Gastroenterology 126(5):1247–1256CrossRefPubMed Atkin W, Rogers P, Cardwell C, Cook C, Cuzick J, Wardle J et al (2004) Wide variation in adenoma detection rates at screening flexible sigmoidoscopy. Gastroenterology 126(5):1247–1256CrossRefPubMed
19.
Zurück zum Zitat Heresbach D, Barrioz T, Lapalus MG, Coumaros D, Bauret P, Potier P et al (2008) Miss rate for colorectal neoplastic polyps: a prospective multicenter study of back-to-back video colonoscopies. Endoscopy 40(4):284–290CrossRefPubMed Heresbach D, Barrioz T, Lapalus MG, Coumaros D, Bauret P, Potier P et al (2008) Miss rate for colorectal neoplastic polyps: a prospective multicenter study of back-to-back video colonoscopies. Endoscopy 40(4):284–290CrossRefPubMed
20.
Zurück zum Zitat Tribonias G, Chlouverakis G, Paspatis GA (2010) How strong is the evidence that high-definition colonoscopy improves polyp detection rate compared with standard white-light colonoscopy? Clin Gastroenterol Hepatol 8(10):903 (author reply 4)CrossRefPubMed Tribonias G, Chlouverakis G, Paspatis GA (2010) How strong is the evidence that high-definition colonoscopy improves polyp detection rate compared with standard white-light colonoscopy? Clin Gastroenterol Hepatol 8(10):903 (author reply 4)CrossRefPubMed
21.
Zurück zum Zitat Subramanian V, Mannath J, Hawkey CJ, Ragunath K (2011) High definition colonoscopy vs. standard video endoscopy for the detection of colonic polyps: a meta-analysis. Endoscopy 43(6):499–505CrossRefPubMed Subramanian V, Mannath J, Hawkey CJ, Ragunath K (2011) High definition colonoscopy vs. standard video endoscopy for the detection of colonic polyps: a meta-analysis. Endoscopy 43(6):499–505CrossRefPubMed
22.
Zurück zum Zitat Tribonias G, Theodoropoulou A, Konstantinidis K, Vardas E, Karmiris K, Chroniaris N et al (2010) Comparison of standard vs high-definition, wide-angle colonoscopy for polyp detection: a randomized controlled trial. Colorectal Dis 12(10 Online):e260-6PubMed Tribonias G, Theodoropoulou A, Konstantinidis K, Vardas E, Karmiris K, Chroniaris N et al (2010) Comparison of standard vs high-definition, wide-angle colonoscopy for polyp detection: a randomized controlled trial. Colorectal Dis 12(10 Online):e260-6PubMed
23.
Zurück zum Zitat Pellise M, Fernandez-Esparrach G, Cardenas A, Sendino O, Ricart E, Vaquero E et al (2008) Impact of wide-angle, high-definition endoscopy in the diagnosis of colorectal neoplasia: a randomized controlled trial. Gastroenterology 135(4):1062–1068CrossRefPubMed Pellise M, Fernandez-Esparrach G, Cardenas A, Sendino O, Ricart E, Vaquero E et al (2008) Impact of wide-angle, high-definition endoscopy in the diagnosis of colorectal neoplasia: a randomized controlled trial. Gastroenterology 135(4):1062–1068CrossRefPubMed
24.
Zurück zum Zitat Le Rhun M, Coron E, Parlier D, Nguyen JM, Canard JM, Alamdari A et al (2006) High resolution colonoscopy with chromoscopy versus standard colonoscopy for the detection of colonic neoplasia: a randomized study. Clin Gastroenterol Hepatol 4(3):349–354CrossRefPubMed Le Rhun M, Coron E, Parlier D, Nguyen JM, Canard JM, Alamdari A et al (2006) High resolution colonoscopy with chromoscopy versus standard colonoscopy for the detection of colonic neoplasia: a randomized study. Clin Gastroenterol Hepatol 4(3):349–354CrossRefPubMed
25.
Zurück zum Zitat Machida H, Sano Y, Hamamoto Y, Muto M, Kozu T, Tajiri H et al (2004) Narrow-band imaging in the diagnosis of colorectal mucosal lesions: a pilot study. Endoscopy 36(12):1094–1098CrossRefPubMed Machida H, Sano Y, Hamamoto Y, Muto M, Kozu T, Tajiri H et al (2004) Narrow-band imaging in the diagnosis of colorectal mucosal lesions: a pilot study. Endoscopy 36(12):1094–1098CrossRefPubMed
26.
Zurück zum Zitat Chiu HM, Chang CY, Chen CC, Lee YC, Wu MS, Lin JT et al (2007) A prospective comparative study of narrow-band imaging, chromoendoscopy, and conventional colonoscopy in the diagnosis of colorectal neoplasia. Gut 56(3):373–379CrossRefPubMed Chiu HM, Chang CY, Chen CC, Lee YC, Wu MS, Lin JT et al (2007) A prospective comparative study of narrow-band imaging, chromoendoscopy, and conventional colonoscopy in the diagnosis of colorectal neoplasia. Gut 56(3):373–379CrossRefPubMed
27.
Zurück zum Zitat Adler A, Pohl H, Papanikolaou IS, Abou-Rebyeh H, Schachschal G, Veltzke-Schlieker W et al (2008) A prospective randomised study on narrow-band imaging versus conventional colonoscopy for adenoma detection: does narrow-band imaging induce a learning effect? Gut 57(1):59–64CrossRefPubMed Adler A, Pohl H, Papanikolaou IS, Abou-Rebyeh H, Schachschal G, Veltzke-Schlieker W et al (2008) A prospective randomised study on narrow-band imaging versus conventional colonoscopy for adenoma detection: does narrow-band imaging induce a learning effect? Gut 57(1):59–64CrossRefPubMed
28.
Zurück zum Zitat Gavin DR, Valori RM, Anderson JT, Donnelly MT, Williams JG, Swarbrick ET (2013) The national colonoscopy audit: a nationwide assessment of the quality and safety of colonoscopy in the UK. Gut 62(2):242–249CrossRefPubMed Gavin DR, Valori RM, Anderson JT, Donnelly MT, Williams JG, Swarbrick ET (2013) The national colonoscopy audit: a nationwide assessment of the quality and safety of colonoscopy in the UK. Gut 62(2):242–249CrossRefPubMed
29.
Zurück zum Zitat Harewood GC, Sharma VK, de Garmo P (2003) Impact of colonoscopy preparation quality on detection of suspected colonic neoplasia. Gastrointest Endosc 58(1):76–79CrossRefPubMed Harewood GC, Sharma VK, de Garmo P (2003) Impact of colonoscopy preparation quality on detection of suspected colonic neoplasia. Gastrointest Endosc 58(1):76–79CrossRefPubMed
30.
Zurück zum Zitat Cirocco WC, Rusin LC (1995) Confirmation of cecal intubation during colonoscopy. Dis Colon Rectum 38(4):402–406CrossRefPubMed Cirocco WC, Rusin LC (1995) Confirmation of cecal intubation during colonoscopy. Dis Colon Rectum 38(4):402–406CrossRefPubMed
31.
Zurück zum Zitat Buchner AM, Shahid MW, Heckman MG, McNeil RB, Cleveland P, Gill KR et al (2010) High-definition colonoscopy detects colorectal polyps at a higher rate than standard white-light colonoscopy. Clin Gastroenterol Hepatol 8(4):364–370CrossRefPubMed Buchner AM, Shahid MW, Heckman MG, McNeil RB, Cleveland P, Gill KR et al (2010) High-definition colonoscopy detects colorectal polyps at a higher rate than standard white-light colonoscopy. Clin Gastroenterol Hepatol 8(4):364–370CrossRefPubMed
32.
Zurück zum Zitat Waldmann E, Britto-Arias M, Gessl I, Heinze G, Salzl P, Sallinger D et al (2015) Endoscopists with low adenoma detection rates benefit from high-definition endoscopy. Surg Endosc 29(2):466–473CrossRefPubMed Waldmann E, Britto-Arias M, Gessl I, Heinze G, Salzl P, Sallinger D et al (2015) Endoscopists with low adenoma detection rates benefit from high-definition endoscopy. Surg Endosc 29(2):466–473CrossRefPubMed
33.
Zurück zum Zitat Read TE, Read JD, Butterly LF (1997) Importance of adenomas 5 mm or less in diameter that are detected by sigmoidoscopy. N Engl J Med 336(1):8–12CrossRefPubMed Read TE, Read JD, Butterly LF (1997) Importance of adenomas 5 mm or less in diameter that are detected by sigmoidoscopy. N Engl J Med 336(1):8–12CrossRefPubMed
34.
Zurück zum Zitat Gurudu SR, Ramirez FC (2013) Quality metrics in endoscopy. Gastroenterol Hepatol 9(4):228–233 Gurudu SR, Ramirez FC (2013) Quality metrics in endoscopy. Gastroenterol Hepatol 9(4):228–233
35.
Zurück zum Zitat Williams JE, Holub JL, Faigel DO (2012) Polypectomy rate is a valid quality measure for colonoscopy: results from a national endoscopy database. Gastrointest Endosc 75(3):576–582CrossRefPubMed Williams JE, Holub JL, Faigel DO (2012) Polypectomy rate is a valid quality measure for colonoscopy: results from a national endoscopy database. Gastrointest Endosc 75(3):576–582CrossRefPubMed
36.
Zurück zum Zitat Johnson DA, Gurney MS, Volpe RJ, Jones DM, VanNess MM, Chobanian SJ et al (1990) A prospective study of the prevalence of colonic neoplasms in asymptomatic patients with an age-related risk. Am J Gastroenterol 85(8):969–974PubMed Johnson DA, Gurney MS, Volpe RJ, Jones DM, VanNess MM, Chobanian SJ et al (1990) A prospective study of the prevalence of colonic neoplasms in asymptomatic patients with an age-related risk. Am J Gastroenterol 85(8):969–974PubMed
37.
Zurück zum Zitat Schoenfeld P, Cash B, Flood A, Dobhan R, Eastone J, Coyle W et al (2005) Colonoscopic screening of average-risk women for colorectal neoplasia. N Engl J Med 352(20):2061–2068CrossRefPubMed Schoenfeld P, Cash B, Flood A, Dobhan R, Eastone J, Coyle W et al (2005) Colonoscopic screening of average-risk women for colorectal neoplasia. N Engl J Med 352(20):2061–2068CrossRefPubMed
Metadaten
Titel
The use of high definition colonoscopy versus standard definition: does it affect polyp detection rate?
verfasst von
John Richardson
Anthony Thaventhiran
Hugh Mackenzie
Benjamin Stubbs
Publikationsdatum
03.11.2017
Verlag
Springer US
Erschienen in
Surgical Endoscopy / Ausgabe 6/2018
Print ISSN: 0930-2794
Elektronische ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-017-5962-6

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