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Zeitschrift für Rheumatologie

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01.12.2013 | Leitthema

Therapeutische Strategien im Frühstadium der systemischen Sklerose

Frühe Diagnose – frühe Symptome – frühe Probleme

verfasst von: Dr. M. Frerix, F.M.P. Meier, W. Hermann, U. Müller-Ladner

Erschienen in: Zeitschrift für Rheumatologie | Ausgabe 10/2013

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Zusammenfassung

Aufgrund der verbesserten diagnostischen Möglichkeiten der letzten Jahrzehnte kann heute die Erkrankung der systemischen Sklerose (SSc) in immer früheren Erkrankungsstadien diagnostiziert werden. Mit der Frühdiagnose der Erkrankung ergeben sich für den Rheumatologen gleichzeitig neue Herausforderungen im klinischen Alltag. In diesem Artikel wird das therapeutische Management der systemischen Sklerose mit einem Schwerpunkt auf die Frühstadien der Erkrankung erläutert. Diagnostik und Therapie früher Symptome, wie dem Raynaud-Phänomen, „puffy fingers“, digitalen Ulzerationen, Calcinosis cutis sowie einer frühen kardiopulmonalen, nephrologischen oder gastrointestinalen Beteiligung, werden diskutiert. Abschließend werden Möglichkeiten und Grenzen der frühen immunmodulatorischen Therapie und autologen Stammzelltransplantation für Patienten mit einem rasch progressiven und schweren Verlauf der Erkrankung besprochen.

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Titel: Therapeutische Strategien im Frühstadium der systemischen Sklerose
Frühe Diagnose – frühe Symptome – frühe Probleme
verfasst von: Dr. M. Frerix
F.M.P. Meier
W. Hermann
U. Müller-Ladner
Publikationsdatum: 01.12.2013
Verlag: Springer Berlin Heidelberg
Erschienen in: Zeitschrift für Rheumatologie / Ausgabe 10/2013
Print ISSN: 0340-1855
Elektronische ISSN: 1435-1250
DOI: https://doi.org/10.1007/s00393-013-1270-2

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