Erschienen in:
01.10.2011 | Letter
Thoracolaparoscopic esophagectomy: further improvement in the multimodal treatment of esophageal cancer
verfasst von:
Theodore Liakakos
Erschienen in:
Surgical Endoscopy
|
Ausgabe 10/2011
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Excerpt
Standardization of multimodal treatment can improve the oncological outcome of patients with a new diagnosis of potentially completely resectable esophageal cancer. Preoperative (neoadjuvant) chemoradiotherapy can improve survival of not only these patients but also those with initially advanced, nonmetastatic, nonresectable with curative intent carcinoma of thoracic esophagus or gastroesophageal junction cancer. A recent study reports that if a complete response (CR) is achieved when assessed with [
18F] fluorodeoxyglucose positron emission tomography (FDG-PET), then prognosis is excellent [
1]. However, this three-mode treatment is associated with a substantial rate of surgical complications and adverse effects of adjuvant treatment. Postoperative complications after an open thoracoabdominal, transhiatal, or transthoracic approach represent even today a serious problem with fatal outcome. With standardization of surgery, particularly in high-volume centers, the rates of surgical morbidity and mortality have dropped. How could this morbidity and short-term postoperative quality of life be improved? …