Ausgabe 1/2021
Inhalt (50 Artikel)
Neuropsychiatric symptoms are early indicators of an upcoming metabolic decline in Alzheimer’s disease
Kok Pin Ng, Tharick A. Pascoal, Sulantha Mathotaarachchi, Yiong Huak Chan, Lai Jiang, Joseph Therriault, Andrea L. Benedet, Monica Shin, Nagaendran Kandiah, Celia M. T. Greenwood, Pedro Rosa-Neto, Serge Gauthier
Cerebral spinal fluid biomarker profiles in CNS infection associated with HSV and VZV mimic patterns in Alzheimer’s disease
Makiko Shinomoto, Takashi Kasai, Harutsugu Tatebe, Fukiko Kitani-Morii, Takuma Ohmichi, Yuzo Fujino, David Allsop, Toshiki Mizuno, Takahiko Tokuda
Aberrations of biochemical indicators in amyotrophic lateral sclerosis: a systematic review and meta-analysis
Yangfan Cheng, Yongping Chen, Huifang Shang
Cross-talks among GBA mutations, glucocerebrosidase, and α-synuclein in GBA-associated Parkinson’s disease and their targeted therapeutic approaches: a comprehensive review
Tapan Behl, Gagandeep Kaur, Ovidiu Fratila, Camelia Buhas, Claudia Teodora Judea-Pusta, Nicoleta Negrut, Cristiana Bustea, Simona Bungau
Multitasking guardian of mitochondrial quality: Parkin function and Parkinson’s disease
Iryna Kamienieva, Jerzy Duszyński, Joanna Szczepanowska
Advances in retina imaging as potential biomarkers for early diagnosis of Alzheimer’s disease
Ying Zhang, Yanjiang Wang, Ce Shi, Meixiao Shen, Fan Lu
Recommendations for the diagnosis and treatment of paroxysmal kinesigenic dyskinesia: an expert consensus in China
Li Cao, Xiaojun Huang, Ning Wang, Zhiying Wu, Cheng Zhang, Weihong Gu, Shuyan Cong, Jianhua Ma, Ling Wei, Yanchun Deng, Qi Fang, Qi Niu, Jin Wang, Zhaoxia Wang, You Yin, Jinyong Tian, Shufen Tian, Hongyan Bi, Hong Jiang, Xiaorong Liu, Yang Lü, Meizhen Sun, Jianjun Wu, Erhe Xu, Tao Chen, Tao Chen, Xu Chen, Wei Li, Shujian Li, Qinghua Li, Xiaonan Song, Ying Tang, Ping Yang, Yun Yang, Min Zhang, Xiong Zhang, Yuhu Zhang, Ruxu Zhang, Yi Ouyang, Jintai Yu, Quanzhong Hu, Qing Ke, Yuanrong Yao, Zhe Zhao, Xiuhe Zhao, Guohua Zhao, Furu Liang, Nan Cheng, Jianhong Han, Rong Peng, Shengdi Chen, Beisha Tang
Ecto-GPR37: a potential biomarker for Parkinson’s disease
Xavier Morató, Paula Garcia-Esparcia, Josep Argerich, Franc Llorens, Inga Zerr, Wojciech Paslawski, Eva Borràs, Eduard Sabidó, Ulla E. Petäjä-Repo, Víctor Fernández-Dueñas, Isidro Ferrer, Per Svenningsson, Francisco Ciruela
An old weapon with a new function: PIWI-interacting RNAs in neurodegenerative diseases
Xiaobing Huang, Garry Wong
Ultrasensitive assays for detection of plasma tau and phosphorylated tau 181 in Alzheimer’s disease: a systematic review and meta-analysis
Xulong Ding, Shuting Zhang, Lijun Jiang, Lu Wang, Tao Li, Peng Lei
Associations of AT(N) biomarkers with neuropsychiatric symptoms in preclinical Alzheimer’s disease and cognitively unimpaired individuals
Kok Pin Ng, Hui Chiew, Pedro Rosa-Neto, Nagaendran Kandiah, Zahinoor Ismail, Serge Gauthier
Pharmacological inhibition of asparaginyl endopeptidase by δ-secretase inhibitor 11 mitigates Alzheimer’s disease-related pathologies in a senescence-accelerated mouse model
Ju Wang, Hui-Jie Hu, Zi-Kai Liu, Jing-Jing Liu, Shan-Shan Wang, Qing Cheng, Hong-Zhuan Chen, Mingke Song
Acrolein scavenger dimercaprol offers neuroprotection in an animal model of Parkinson’s disease: implication of acrolein and TRPA1
Liangqin Shi, Yazhou Lin, Yucheng Jiao, Seth A. Herr, Jonathan Tang, Edmond Rogers, Zhengli Chen, Riyi Shi
Effectiveness and mechanisms of adipose-derived stem cell therapy in animal models of Parkinson’s disease: a systematic review and meta-analysis
Keya Li, Xinyue Li, Guiying Shi, Xuepei Lei, Yiying Huang, Lin Bai, Chuan Qin
COVID-19 and Alzheimer’s disease: how one crisis worsens the other
Xiaohuan Xia, Yi Wang, Jialin Zheng
Neurodegenerative diseases: a hotbed for splicing defects and the potential therapies
Dunhui Li, Craig Stewart McIntosh, Frank Louis Mastaglia, Steve Donald Wilton, May Thandar Aung-Htut
Disruption of orbitofrontal-hypothalamic projections in a murine ALS model and in human patients
David Bayer, Stefano Antonucci, Hans-Peter Müller, Rami Saad, Luc Dupuis, Volker Rasche, Tobias M. Böckers, Albert C. Ludolph, Jan Kassubek, Francesco Roselli
Associations of cerebrospinal fluid amyloidogenic nanoplaques with cytokines in Alzheimer’s disease
Mari Aksnes, Hans Christian D. Aass, Ann Tiiman, Trine Holt Edwin, Lars Terenius, Nenad Bogdanović, Vladana Vukojević, Anne-Brita Knapskog
Parkinson’s disease–associated VPS35 mutant reduces mitochondrial membrane potential and impairs PINK1/Parkin-mediated mitophagy
Kai Yu Ma, Michiel R. Fokkens, Fulvio Reggiori, Muriel Mari, Dineke S. Verbeek
Differential seeding and propagating efficiency of α-synuclein strains generated in different conditions
Di Liu, Jian-Jun Guo, Ji-Hui Su, Alexander Svanbergsson, Lin Yuan, Caroline Haikal, Wen Li, Gunnar Gouras, Jia-Yi Li
Metabolic changes in an animal model of amyotrophic lateral sclerosis evaluated by [18F]-FDG positron emission tomography
Bruno Lima Giacobbo, Tomás Mediavilla, Daniel J. Marcellino, Fahad Sultan
The effects of transcranial direct current stimulation on gait in patients with Parkinson’s disease: a systematic review
Fateme Pol, Mohammad Ali Salehinejad, Hamzeh Baharlouei, Michael A. Nitsche
Inhibition of lysine methyltransferase G9a/GLP reinstates long-term synaptic plasticity and synaptic tagging/capture by facilitating protein synthesis in the hippocampal CA1 area of APP/PS1 mouse model of Alzheimer’s disease
Javan Lee Tze Han, Karen Ka Lam Pang, Sheila Rui Xia Ang, Mahima Sharma, Sreedharan Sajikumar
Language training for oral and written naming impairment in primary progressive aphasia: a review
Ilaria Pagnoni, Elena Gobbi, Enrico Premi, Barbara Borroni, Giuliano Binetti, Maria Cotelli, Rosa Manenti
Several miRNAs derived from serum extracellular vesicles are potential biomarkers for early diagnosis and progression of Parkinson’s disease
Shulei He, Lu Huang, Ci Shao, Tiejian Nie, Li Xia, Bozhou Cui, Fangfang Lu, Lin Zhu, Bolin Chen, Qian Yang
Multivariable clinical-genetic model for predicting dyskinesia in early-onset Parkinson’s disease
Yong-Ping Chen, Ru-Wei Ou, Xiao-Jing Gu, Ling-Yu Zhang, Bei Cao, Yan-Bing Hou, Kun-Cheng Liu, Jun-Yu Lin, Qian-Qian Wei, Bi Zhao, Ying Wu, Hui-Fang Shang
Optimization of cerebral organoids: a more qualified model for Alzheimer’s disease research
Feng-Chen Bi, Xin-He Yang, Xiao-Yu Cheng, Wen-Bin Deng, Xiao-Li Guo, Hui Yang, Yin Wang, Juan Li, Yao Yao
The Gold Coast criteria increases the diagnostic sensitivity for amyotrophic lateral sclerosis in a Chinese population
Dongchao Shen, Xunzhe Yang, Yanying Wang, Di He, Xiaohan Sun, Zhengyi Cai, Jinyue Li, Mingsheng Liu, Liying Cui
A perspective on therapies for amyotrophic lateral sclerosis: can disease progression be curbed?
Xiaojiao Xu, Dingding Shen, Yining Gao, Qinming Zhou, You Ni, Huanyu Meng, Hongqin Shi, Weidong Le, Shengdi Chen, Sheng Chen
Roles of physical exercise in neurodegeneration: reversal of epigenetic clock
Miao Xu, JiaYi Zhu, Xian-Dong Liu, Ming-Ying Luo, Nan-Jie Xu
Neurofilament light and heterogeneity of disease progression in amyotrophic lateral sclerosis: development and validation of a prediction model to improve interventional trials
Simon Witzel, Felix Frauhammer, Petra Steinacker, David Devos, Pierre-François Pradat, Vincent Meininger, Steffen Halbgebauer, Patrick Oeckl, Joachim Schuster, Simon Anders, Johannes Dorst, Markus Otto, Albert C. Ludolph
Predictability of polygenic risk score for progression to dementia and its interaction with APOE ε4 in mild cognitive impairment
Jung-Min Pyun, Young Ho Park, Keon-Joo Lee, SangYun Kim, Andrew J. Saykin, Kwangsik Nho
Mitochondrial links between brain aging and Alzheimer’s disease
Heather M. Wilkins, Russell H. Swerdlow
NMDAR-dependent somatic potentiation of synaptic inputs is correlated with β amyloid-mediated neuronal hyperactivity
Yifei Bao, Xin Yang, Yi Fu, Zhengyan Li, Ru Gong, Wei Lu
Disruption of the white matter structural network and its correlation with baseline progression rate in patients with sporadic amyotrophic lateral sclerosis
Wenbin Li, Qianqian Wei, Yanbing Hou, Du Lei, Yuan Ai, Kun Qin, Jing Yang, Graham J. Kemp, Huifang Shang, Qiyong Gong
Multi-mechanical waves against Alzheimer’s disease pathology: a systematic review
Francisca Monteiro, Ioannis Sotiropoulos, Óscar Carvalho, Nuno Sousa, Filipe S. Silva
Dense core vesicle markers in CSF and cortical tissues of patients with Alzheimer’s disease
Neus Barranco, Virginia Plá, Daniel Alcolea, Irene Sánchez-Domínguez, Reiner Fischer-Colbrie, Isidro Ferrer, Alberto Lleó, Fernando Aguado
Novel multivalent design of a monoclonal antibody improves binding strength to soluble aggregates of amyloid beta
Fadi Rofo, Jos Buijs, Ronny Falk, Ken Honek, Lars Lannfelt, Anna M. Lilja, Nicole G. Metzendorf, Tobias Gustavsson, Dag Sehlin, Linda Söderberg, Greta Hultqvist
Astrocyte dysfunction in Parkinson's disease: from the perspectives of transmitted α-synuclein and genetic modulation
Changjing Wang, Tongtong Yang, Meiyu Liang, Junxia Xie, Ning Song
Genetic spectrum and clinical features in a cohort of Chinese patients with autosomal recessive cerebellar ataxias
Hao-Ling Cheng, Ya-Ru Shao, Yi Dong, Hai-Lin Dong, Lu Yang, Yin Ma, Ying Shen, Zhi-Ying Wu
Correction to: Neurodegenerative diseases: a hotbed for splicing defects and the potential therapies
Dunhui Li, Craig Stewart McIntosh, Frank Louis Mastaglia, Steve Donald Wilton, May Thandar Aung-Htut
A natural history comparison of SOD1-mutant patients with amyotrophic lateral sclerosis between Chinese and German populations
Lu Tang, Johannes Dorst, Lu Chen, Xiaolu Liu, Yan Ma, Kornelia Günther, Sebastian Michels, Kathrin Müller, Axel Freischmidt, Jochen H. Weishaupt, Dongsheng Fan, Albert C. Ludolph
Astrocytes and retrograde degeneration of nigrostriatal dopaminergic neurons in Parkinson’s disease: removing axonal debris
Ingrid Morales, Ricardo Puertas-Avendaño, Alberto Sanchez, Adrian Perez-Barreto, Clara Rodriguez-Sabate, Manuel Rodriguez
Extensive frontal focused ultrasound mediated blood–brain barrier opening for the treatment of Alzheimer’s disease: a proof-of-concept study
So Hee Park, Kyoungwon Baik, Seun Jeon, Won Seok Chang, Byoung Seok Ye, Jin Woo Chang
The role of pathological tau in synaptic dysfunction in Alzheimer’s diseases
Moxin Wu, Manqing Zhang, Xiaoping Yin, Kai Chen, Zhijian Hu, Qin Zhou, Xianming Cao, Zhiying Chen, Dan Liu
New perspectives on cytoskeletal dysregulation and mitochondrial mislocalization in amyotrophic lateral sclerosis
Frances Theunissen, Phillip K. West, Samuel Brennan, Bojan Petrović, Kosar Hooshmand, P. Anthony Akkari, Matt Keon, Boris Guennewig
TLR2 and TLR4 in Parkinson’s disease pathogenesis: the environment takes a toll on the gut
Anastazja M. Gorecki, Chidozie C. Anyaegbu, Ryan S. Anderton
Effects of transcranial ultrasound stimulation pulsed at 40 Hz on Aβ plaques and brain rhythms in 5×FAD mice
Mincheol Park, Gia Minh Hoang, Thien Nguyen, Eunkyung Lee, Hyun Jin Jung, Youngshik Choe, Moon Hwan Lee, Jae Youn Hwang, Jae Gwan Kim, Tae Kim
Gram-negative bacteria and their lipopolysaccharides in Alzheimer’s disease: pathologic roles and therapeutic implications
Hyeon soo Kim, Sujin Kim, Soo Jung Shin, Yong Ho Park, Yunkwon Nam, Chae won Kim, Kang won Lee, Sung-Min Kim, In Duk Jung, Hyun Duk Yang, Yeong-Min Park, Minho Moon
Plasma glial fibrillary acidic protein and neurofilament light chain for the diagnostic and prognostic evaluation of frontotemporal dementia
Nuole Zhu, Miguel Santos-Santos, Ignacio Illán-Gala, Victor Montal, Teresa Estellés, Isabel Barroeta, Miren Altuna, Javier Arranz, Laia Muñoz, Olivia Belbin, Isabel Sala, Maria Belén Sánchez-Saudinós, Andrea Subirana, Laura Videla, Jordi Pegueroles, Rafael Blesa, Jordi Clarimón, Maria Carmona-Iragui, Juan Fortea, Alberto Lleó, Daniel Alcolea