Erschienen in:
29.12.2022 | Original Article
Treatment of Early Glottic cancer with Transoral Laser Microsurgery: An Australian Experience
verfasst von:
Navid Ahmadi, Danielle Stone, Murray Stokan, Hedley Coleman, Gillian Heller, Mark Smith, Faruque Riffat, Akshay Kudpaje, Michael Veness, Carsten E Palme
Erschienen in:
Indian Journal of Otolaryngology and Head & Neck Surgery
|
Ausgabe 2/2023
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Abstract
Introduction
Early laryngeal carcinomas may be treated by transoral laser microsurgery (TLM) or external beam radiotherapy. We review our experience of surgical treatment of laryngeal pre-malignant and malignant lesions over the past 15 years in a high-volume head neck unit.
Methods
A review of a prospective patient database of patients with laryngeal SCC, who were treated with CO2 TLM between 2004 and 2019 was carried out.
Results
83 patients with a mean age of 67.7 (SD: 10.6) years underwent primary curative TLM for T1a/b SCC. 5-year overall survival was 93.2% (95%CI 86.9–100%), disease free survival was 86.0% (95%CI 78.1–94.6%), locoregional control was 91.2% (95%CI: 85.1–97.7%) and larynx preservation rate of 95.1% at 5 years.
Conclusion
TLM is an excellent treatment modality for T1 early glottic SCC, with excellent locoregional control and disease-free survival. It is minimally invasive, outpatient-based, and cost-effective procedure preserving upper aerodigestive tract dysfunction for all activities of daily living.