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24.04.2020 | Case Presentation Corner

Unusual high 99mTc-3,3-diphosphono-1,2-propanodicarboxylic acid (99mTc-DPD) tracer deposition on a heart scintigraphy in a patient with AL amyloidosis: A case report

verfasst von: Yvan R. Persia-Paulino, MD, Javier Cuevas-Perez, MD, Rodrigo Fernandez-Asensio, MD, Alejandro Junco-Vicente, MD, Jose Rozado-Castano, MD, PhD, Santiago Colunga, MD, Helena Cigarran, MD, Juan Calvo, MD, Alfredo Laverde, MD, Osiris Persia, MD, Esmeralda Capin-Sampedro, MD

Erschienen in: Journal of Nuclear Cardiology | Ausgabe 3/2021

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Abstract

We present a case of a 40-year-old Spanish man with cardiac amyloidosis in which a Tc-99m-3,3-diphosphono-1,2-propanodicarboxylic acid (Tc-99m-DPD) scintigraphy was strongly suggestive of cardiac amyloidosis by transthyretin (ATTR) but endomyocardial biopsy (EB) analyzed by immunohistochemistry demonstrated a light chain amyloidosis (AL). Even though the Tc-99m-DPD has proven in different published papers that has high sensibility and specificity for differentiating AL and ATTR cardiac amyloidosis, we present an unusual case of an AL cardiac amyloidosis with a Perugini grade 3 on the scintigraphy. Diagnostic approach of cardiac amyloidosis following consensus documents is discussed to avoid diagnostic mistakes based on imaging techniques.

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Titel: Unusual high 99mTc-3,3-diphosphono-1,2-propanodicarboxylic acid (99mTc-DPD) tracer deposition on a heart scintigraphy in a patient with AL amyloidosis: A case report
verfasst von: Yvan R. Persia-Paulino, MD
Javier Cuevas-Perez, MD
Rodrigo Fernandez-Asensio, MD
Alejandro Junco-Vicente, MD
Jose Rozado-Castano, MD, PhD
Santiago Colunga, MD
Helena Cigarran, MD
Juan Calvo, MD
Alfredo Laverde, MD
Osiris Persia, MD
Esmeralda Capin-Sampedro, MD
Publikationsdatum: 24.04.2020
Verlag: Springer International Publishing
Erschienen in: Journal of Nuclear Cardiology / Ausgabe 3/2021
Print ISSN: 1071-3581
Elektronische ISSN: 1532-6551
DOI: https://doi.org/10.1007/s12350-020-02107-2

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Unusual high 99mTc-3,3-diphosphono-1,2-propanodicarboxylic acid (99mTc-DPD) tracer deposition on a heart scintigraphy in a patient with AL amyloidosis: A case report

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