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Erschienen in:
19.11.2020 | Original Article
Usefulness of dual-layer spectral CT in follow-up examinations: diagnosing recurrent squamous cell carcinomas in the head and neck
Erschienen in: Japanese Journal of Radiology | Ausgabe 4/2021
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Purpose
To evaluate the usefulness of dual-energy analyses using dual-layer spectral CT (DLSCT) for diagnosing recurrent lesions of head and neck squamous cell carcinoma (HNSCC).
Materials and methods
The study population comprised 62 patients with a history of HNSCC. Attenuation values on conventional 120-kVp images and 40-keV virtual monochromatic images (VMIs) and iodine concentration (IC) were compared between recurrent lesions and post-treatment changes or non-recurrent nodes using the Mann–Whitney U test. Receiver-operating characteristic (ROC) analysis was used to assess the ability of attenuation values and IC to diagnose recurrent lesions.
Results
Attenuation values for 120-kVp and 40-keV images and IC of local recurrent lesions were significantly higher than those of post-treatment changes (p < 0.001), whereas recurrent nodes showed significantly lower attenuation values for both 120 kVp and 40 keV and IC than non-recurrent nodes (p < 0.001). Area under the ROC curves for 120-kVp images, 40-keV images, and IC to diagnose local recurrences were 0.912, 0.992, and 0.984, respectively, and those to diagnose recurrent nodes were 0.819, 0.922, and 0.934, respectively.
Conclusions
Dual-energy images using DLSCT, particularly 40-keV VMIs and IC, may help in diagnosing recurrent lesions of HNSCC.