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Current Infectious Disease Reports
Erschienen in: Current Infectious Disease Reports 4/2017

01.04.2017 | Healthcare Associated Infections (G Bearman and D. Morgan, Section Editors)

Whole Genome Sequencing—Implications for Infection Prevention and Outbreak Investigations

verfasst von: Kyle J. Popovich, Evan S. Snitkin

Erschienen in: Current Infectious Disease Reports | Ausgabe 4/2017

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Abstract

Purpose of Review

Whole genome sequencing (WGS) is a laboratory method that has emerged as a promising tool for epidemiologic investigations.

Recent Findings

Genomic epidemiology approaches have been utilized in outbreak settings, community settings, within acute care hospitals, and across healthcare facilities to better understand transmission and spread of potential pathogens. These studies have highlighted how essential robust epidemiologic data is in these analyses as well as how results can be translated into clinical practice and infection control and prevention.

Summary

Existing studies have highlighted both the promise and challenges of using WGS as an epidemiologic tool in a community and healthcare setting and across a region. Costs for performing and interpreting WGS analyses are decreasing, and availability of and experience with WGS analyses in healthcare epidemiology are increasing. With these favorable trends, this laboratory method soon could emerge as the gold standard for epidemiologic evaluations.
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Metadaten
Titel
Whole Genome Sequencing—Implications for Infection Prevention and Outbreak Investigations
verfasst von
Kyle J. Popovich
Evan S. Snitkin
Publikationsdatum
01.04.2017
Verlag
Springer US
Erschienen in
Current Infectious Disease Reports / Ausgabe 4/2017
Print ISSN: 1523-3847
Elektronische ISSN: 1534-3146
DOI
https://doi.org/10.1007/s11908-017-0570-0

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