Skip to main content
Erschienen in: Der Unfallchirurg 5/2004

01.05.2004 | Leitthema

Wirbelkörperersatz in der Wirbelsäulenchirurgie

verfasst von: Priv.-Doz. Dr. F. Kandziora, K. J. Schnake, C. K. Klostermann, N. P. Haas

Erschienen in: Die Unfallchirurgie | Ausgabe 5/2004

Einloggen, um Zugang zu erhalten

Zusammenfassung

Der Wirbelkörperersatz kann sowohl mit autologen und allogenen Knochenmaterialien als auch mit Wirbelkörperersatzimplantaten, sog. Cages, durchgeführt werden. Die seit Kurzem verfügbaren expandierenden Cages werden zunehmend häufiger eingesetzt. Ziel dieser Arbeit war es daher, die bisher verfügbaren biomechanischen und klinischen Daten expandierbarer Korporektomie-Cages auf der Basis eigener experimenteller Untersuchungen und klinischer Erfahrungen zusammenzufassen und den etablierten Implantaten und Transplantaten gegenüber zu stellen.
Die neuen expandierbaren Cages weisen einige operationstechnische Vorteile auf, wenn die chirurgischen Besonderheiten dieser Implantate Beachtung finden. Unter biomechanischen Gesichtspunkten sind zervikale und thorakolumbale expandierbare Cages in Bezug auf die dreidimensionale Steifigkeit nicht expandierbaren Formen zumindest ebenbürtig. Designvariationen scheinen für die biomechanische Stabilität nur eine untergeordnete Rolle zu spielen. Auch in Bezug auf die mittelfristigen klinischen Ergebnisse bei der Versorgung von Frakturen, Metastasen und Spondylodiszitiden in der zervikalen und thorakolumbalen Wirbelsäule sind anhand derzeit vorliegender Daten keine wesentlichen Unterschiede zwischen expandierbaren und nicht expandierbaren Cages zu erwarten. Unklar bleibt momentan jedoch, ob sich das erhöhte „stress shielding“ expandierbarer Cages längerfristig negativ auf die erwünschte Fusion auswirken kann.
Literatur
1.
Zurück zum Zitat Aebi M, Etter C, Kehl T, Thalgott J (1988) The internal skeletal fixation system. A new treatment of thoracolumbar fractures and other spinal disorders. Clin Orthop 227: 30–43PubMed Aebi M, Etter C, Kehl T, Thalgott J (1988) The internal skeletal fixation system. A new treatment of thoracolumbar fractures and other spinal disorders. Clin Orthop 227: 30–43PubMed
2.
Zurück zum Zitat Alici E, Alku O, Dost S (1990) Prothesis designed for vertebral body replacement. J Biomech 23: 799–809PubMed Alici E, Alku O, Dost S (1990) Prothesis designed for vertebral body replacement. J Biomech 23: 799–809PubMed
3.
Zurück zum Zitat Anderson L, Stivers B, Park WI 3rd (1974) Multiple level anterior cervical spine fusion. A report of 16 cases. J Trauma 14: 653–674,PubMed Anderson L, Stivers B, Park WI 3rd (1974) Multiple level anterior cervical spine fusion. A report of 16 cases. J Trauma 14: 653–674,PubMed
4.
Zurück zum Zitat Arrington ED, Smith W, Chambers HG, Bucknell AL, Davino NA (1996) Complications of iliac crest bone graft harvesting. Clin Orthop 329: 300–309PubMed Arrington ED, Smith W, Chambers HG, Bucknell AL, Davino NA (1996) Complications of iliac crest bone graft harvesting. Clin Orthop 329: 300–309PubMed
5.
6.
Zurück zum Zitat Bankwart JC, Asher M, Hassanein RS (1995) Iliac crest bone graft harvest donor site morbidity. A statistical evaluation. Spine 20: 1055–1060PubMed Bankwart JC, Asher M, Hassanein RS (1995) Iliac crest bone graft harvest donor site morbidity. A statistical evaluation. Spine 20: 1055–1060PubMed
7.
Zurück zum Zitat Been H (1991) Anterior decompression and stabilization of thoracolumbar burst fractures by the use of the Slot-Zielke device. Spine 16: 70–77PubMed Been H (1991) Anterior decompression and stabilization of thoracolumbar burst fractures by the use of the Slot-Zielke device. Spine 16: 70–77PubMed
8.
Zurück zum Zitat Benzel EC (1997) Biomechanics of cervical spine surgery for tumor and degenerative diseases. Neurol Med Chir (Tokyo) 37: 583–593 Benzel EC (1997) Biomechanics of cervical spine surgery for tumor and degenerative diseases. Neurol Med Chir (Tokyo) 37: 583–593
9.
Zurück zum Zitat Blauth M, Knop C, Bastian L (1997) Behandlungsstrategie und Ergebnisse bei Frakturen der BWS und LWS. Hefte Z Unfallchirurg 268: 171–179 Blauth M, Knop C, Bastian L (1997) Behandlungsstrategie und Ergebnisse bei Frakturen der BWS und LWS. Hefte Z Unfallchirurg 268: 171–179
10.
Zurück zum Zitat Blauth M, Knop C, Bastian L, Lobenhofer P (1997) Neue Entwicklungen in der Chirurgie der verletzten Wirbelsäule. Orthopäde 26: 437–449 Blauth M, Knop C, Bastian L, Lobenhofer P (1997) Neue Entwicklungen in der Chirurgie der verletzten Wirbelsäule. Orthopäde 26: 437–449
11.
Zurück zum Zitat Boden SD, Martin GJ, Horton WC, Truss TL, Sandhu HS (1998) Laproscopic anterior spinal arthrodesis with rh BMP-2 in a titanium interbody threaded cage. J Spinal Disord 11: 95–101PubMed Boden SD, Martin GJ, Horton WC, Truss TL, Sandhu HS (1998) Laproscopic anterior spinal arthrodesis with rh BMP-2 in a titanium interbody threaded cage. J Spinal Disord 11: 95–101PubMed
12.
Zurück zum Zitat Bouchard J, Koka A, Bensusan JS, Stevenson JS, Emery SE (1994) Effects of radiation on posterior spinal fusion: A rabbit model. Spine 19: 1836–41PubMed Bouchard J, Koka A, Bensusan JS, Stevenson JS, Emery SE (1994) Effects of radiation on posterior spinal fusion: A rabbit model. Spine 19: 1836–41PubMed
13.
Zurück zum Zitat Brantigan JW, McAffee AP, Cunningham BW (1994) Interbody lumbar fusion using a carbon fiber implant versus allograft bone. An investigational study in the Spanish goat. Spine 19: 1436–1444PubMed Brantigan JW, McAffee AP, Cunningham BW (1994) Interbody lumbar fusion using a carbon fiber implant versus allograft bone. An investigational study in the Spanish goat. Spine 19: 1436–1444PubMed
14.
Zurück zum Zitat Brantigan JW, Steffi A, Geiger JM (1991) A carbon fiber implant to aid interbody lumbar fusion. Mechanical testing. Spine 16: 277–282 Brantigan JW, Steffi A, Geiger JM (1991) A carbon fiber implant to aid interbody lumbar fusion. Mechanical testing. Spine 16: 277–282
15.
Zurück zum Zitat Brodke DS, Dick J, Kunz DN, McCabe R, Zdeblick TA (1997) Posterior lumbar interbody fusion. A biomechanical comparison, including a new threaded cage. Spine 22: 26–31CrossRefPubMed Brodke DS, Dick J, Kunz DN, McCabe R, Zdeblick TA (1997) Posterior lumbar interbody fusion. A biomechanical comparison, including a new threaded cage. Spine 22: 26–31CrossRefPubMed
16.
Zurück zum Zitat Brooke NS, Rorke A, King AT, Gullan RW (1997) Preliminary experience of carbon fibre cage prostheses for treatment of cervical spine disorders. Br J Neurosurg 11: 221–227CrossRefPubMed Brooke NS, Rorke A, King AT, Gullan RW (1997) Preliminary experience of carbon fibre cage prostheses for treatment of cervical spine disorders. Br J Neurosurg 11: 221–227CrossRefPubMed
17.
Zurück zum Zitat Burger EH, Klein-Nulend J, Veldhuijzen JP (1992) Mechanical stress and osteogenesis in vitro. J Bone Mineral Res 7: 327–401 Burger EH, Klein-Nulend J, Veldhuijzen JP (1992) Mechanical stress and osteogenesis in vitro. J Bone Mineral Res 7: 327–401
18.
Zurück zum Zitat Carter DR, Wong M (1988) Mechanical stresses and endochondral ossification in the chondroepiphysis. J Orthop Res 6: 148–154PubMed Carter DR, Wong M (1988) Mechanical stresses and endochondral ossification in the chondroepiphysis. J Orthop Res 6: 148–154PubMed
19.
Zurück zum Zitat Cunningham BW, Kanayama M, Parker LM (1999) Osteogenic protein versus autologous interbody arthrodesis in the sheep thoracic spine. A endoscopic study using the Bagby and Kuslich interbody fusion device. Spine 24: 509–518CrossRefPubMed Cunningham BW, Kanayama M, Parker LM (1999) Osteogenic protein versus autologous interbody arthrodesis in the sheep thoracic spine. A endoscopic study using the Bagby and Kuslich interbody fusion device. Spine 24: 509–518CrossRefPubMed
20.
Zurück zum Zitat Daniaux H, Seykora P, Genelin A, Lang T, Kathrein A (1991) Application of posterior plating and modifications in thoracolumbar spine injuries. Indication, techniques and results. Spine 16 (Suppl): 125–133 Daniaux H, Seykora P, Genelin A, Lang T, Kathrein A (1991) Application of posterior plating and modifications in thoracolumbar spine injuries. Indication, techniques and results. Spine 16 (Suppl): 125–133
21.
Zurück zum Zitat Dennis S, Watkins R, Landaker S, Dillin W, Springer D (1989) Comparison of disc space heights after anterior lumbar interbody fusion. Spine 14: 876–878PubMed Dennis S, Watkins R, Landaker S, Dillin W, Springer D (1989) Comparison of disc space heights after anterior lumbar interbody fusion. Spine 14: 876–878PubMed
22.
Zurück zum Zitat DiAngelo DJ, Foley K, Vossel KA, Rampersaud YR, Jansen TH (2000) Anterior cervical plating reverses load transfer through multilevel strut-grafts. Spine 25: 783–795CrossRefPubMed DiAngelo DJ, Foley K, Vossel KA, Rampersaud YR, Jansen TH (2000) Anterior cervical plating reverses load transfer through multilevel strut-grafts. Spine 25: 783–795CrossRefPubMed
23.
Zurück zum Zitat Do Koh Y, Lin T, Won You J, Eck J, An HS (2001) A biomechanical comparison of modern anterior and posterior plate fixation of the cervical spine. Spine: 15–21 Do Koh Y, Lin T, Won You J, Eck J, An HS (2001) A biomechanical comparison of modern anterior and posterior plate fixation of the cervical spine. Spine: 15–21
24.
Zurück zum Zitat Dorai Z, Morgan H, Coimbra C (2003) Titanium cage reconstruction after cervical corpectomy. J Neurosurg 99 (Suppl): 3–7 Dorai Z, Morgan H, Coimbra C (2003) Titanium cage reconstruction after cervical corpectomy. J Neurosurg 99 (Suppl): 3–7
25.
Zurück zum Zitat Eleraky MA, LlanosC, Sonntag VK (1999) Cervical corpectomy: report of 185 cases and review of the literature. Can J Neurosurg 90 (Suppl): 35–41 Eleraky MA, LlanosC, Sonntag VK (1999) Cervical corpectomy: report of 185 cases and review of the literature. Can J Neurosurg 90 (Suppl): 35–41
26.
Zurück zum Zitat Foley KT, DiAngelo D, Rampersaud YR, Vossel KA, Jansen TH (1999) The in vitro effects of instrumentation on multilevel cervical strut-graft mechanics. Spine 24: 2366–2376CrossRefPubMed Foley KT, DiAngelo D, Rampersaud YR, Vossel KA, Jansen TH (1999) The in vitro effects of instrumentation on multilevel cervical strut-graft mechanics. Spine 24: 2366–2376CrossRefPubMed
27.
Zurück zum Zitat Freidberg SR, Gumley G, Pfeifer BA, Hybels RL (1990) Vascularized fibular graft to replace resected cervical vertebral bodies. Case report. J Neurosurg 72: 519–20 Freidberg SR, Gumley G, Pfeifer BA, Hybels RL (1990) Vascularized fibular graft to replace resected cervical vertebral bodies. Case report. J Neurosurg 72: 519–20
28.
Zurück zum Zitat Goh JC, Wong H, Thambyah A, Yu CS (2000) Influence of PLIF cage size on lumbar spine stability. Spine 25: 35–39CrossRefPubMed Goh JC, Wong H, Thambyah A, Yu CS (2000) Influence of PLIF cage size on lumbar spine stability. Spine 25: 35–39CrossRefPubMed
29.
Zurück zum Zitat Gonzalez-Darder JM, Atienza C, Molla F (2001) Biomechanical evaluation of an anterior cervical plate-cage fixation system. Neurocirugia (Astur) 12: 152–157 Gonzalez-Darder JM, Atienza C, Molla F (2001) Biomechanical evaluation of an anterior cervical plate-cage fixation system. Neurocirugia (Astur) 12: 152–157
30.
Zurück zum Zitat Goulet JA, Senunas L, Desilva GL, Greenfield ML (1997) Autogenous iliac crest bone graft. Complications and functional assessment. Clin Orthop 339: 76–81PubMed Goulet JA, Senunas L, Desilva GL, Greenfield ML (1997) Autogenous iliac crest bone graft. Complications and functional assessment. Clin Orthop 339: 76–81PubMed
31.
Zurück zum Zitat Grubb MR, Curreer B, Shih JS, Bonin V, Grabowski JJ, Chao EY (1998) Biomechanical evaluation of anterior cervical spine stabilization. Spine 23: 886–892CrossRefPubMed Grubb MR, Curreer B, Shih JS, Bonin V, Grabowski JJ, Chao EY (1998) Biomechanical evaluation of anterior cervical spine stabilization. Spine 23: 886–892CrossRefPubMed
32.
Zurück zum Zitat Hacker RJ (2002) Threaded cages for degenerative cervical disease. Clin Orthop 394: 39–46PubMed Hacker RJ (2002) Threaded cages for degenerative cervical disease. Clin Orthop 394: 39–46PubMed
33.
Zurück zum Zitat Hecht BP, Fischgrund J, Herkowitz HN, Penman L, Toth JM, Shirkhoda A (1999) The use of recombinant human bone morphogenetic protein 2 (rhBMP-2) to promote spinal fusion in a nonhuman primate anterior interbody fusion model. Spine 24: 629–636CrossRefPubMed Hecht BP, Fischgrund J, Herkowitz HN, Penman L, Toth JM, Shirkhoda A (1999) The use of recombinant human bone morphogenetic protein 2 (rhBMP-2) to promote spinal fusion in a nonhuman primate anterior interbody fusion model. Spine 24: 629–636CrossRefPubMed
34.
Zurück zum Zitat Hollowell JP, Vollmer D, Wilson CR, Pintar FA, Yoganandan N (1996) Biomechanical analysis of thoracolumbar interbody constructs. How important is the endplate? Spine 21: 1032–1036CrossRefPubMed Hollowell JP, Vollmer D, Wilson CR, Pintar FA, Yoganandan N (1996) Biomechanical analysis of thoracolumbar interbody constructs. How important is the endplate? Spine 21: 1032–1036CrossRefPubMed
35.
Zurück zum Zitat Hussein AA, El-Karef. E, Hafez M (2001) Reconstructive surgery in spinal tumours. Eur J Surg Oncol 27: 196–199CrossRefPubMed Hussein AA, El-Karef. E, Hafez M (2001) Reconstructive surgery in spinal tumours. Eur J Surg Oncol 27: 196–199CrossRefPubMed
36.
Zurück zum Zitat Isomi T, Panjabi M, Wang JL, Vaccaro AR, Garfin SR, Patel T (1999) Stabilizing potential of anterior cervical plates in multilevel corpectomies. Spine 24: 2219–2223CrossRefPubMed Isomi T, Panjabi M, Wang JL, Vaccaro AR, Garfin SR, Patel T (1999) Stabilizing potential of anterior cervical plates in multilevel corpectomies. Spine 24: 2219–2223CrossRefPubMed
37.
Zurück zum Zitat Janssen ME, Lam C, Beckham R (2001) Outcomes of allogenic cages in anterior and posterior lumbar interbody fusion. Review. Eur Spine J 10 (Suppl): 158–168CrossRef Janssen ME, Lam C, Beckham R (2001) Outcomes of allogenic cages in anterior and posterior lumbar interbody fusion. Review. Eur Spine J 10 (Suppl): 158–168CrossRef
38.
Zurück zum Zitat Jenis LG, Dunn E, An HS (1999) Metastatic disease of the cervical spine. A review. Clin Orthop 359: 89–103PubMed Jenis LG, Dunn E, An HS (1999) Metastatic disease of the cervical spine. A review. Clin Orthop 359: 89–103PubMed
39.
Zurück zum Zitat Jost B, Cripton P, Lund T, Oxland TR, Lippuner K, Jaeger P, Nolte LP (1998) Compressive strength of interbody cages in the lumbar spine: the effect of cage shape, posterior instrumentation and bone density. Eur Spine J 7: 132–141PubMed Jost B, Cripton P, Lund T, Oxland TR, Lippuner K, Jaeger P, Nolte LP (1998) Compressive strength of interbody cages in the lumbar spine: the effect of cage shape, posterior instrumentation and bone density. Eur Spine J 7: 132–141PubMed
40.
Zurück zum Zitat Kaden B, Koch W, Varchim-Schultheiß K, Wunsch M, Fuhrmann G (1996) Biomechanical studies of transthoracic vertebral body replacement with autologous bone grafts (fibula and rib). Neurosurg Rev 19: 17–21PubMed Kaden B, Koch W, Varchim-Schultheiß K, Wunsch M, Fuhrmann G (1996) Biomechanical studies of transthoracic vertebral body replacement with autologous bone grafts (fibula and rib). Neurosurg Rev 19: 17–21PubMed
41.
Zurück zum Zitat Kanayama M, Cunningham B, Haggerty CJ, Abumi K, Kaneda K, McAfee PC (2000) In vitro biomechanical investigation of the stability and stress-shielding effect of lumbar interbody fusion devices. J Neurosurg (Spine 2) 93: 259–265 Kanayama M, Cunningham B, Haggerty CJ, Abumi K, Kaneda K, McAfee PC (2000) In vitro biomechanical investigation of the stability and stress-shielding effect of lumbar interbody fusion devices. J Neurosurg (Spine 2) 93: 259–265
42.
Zurück zum Zitat Kanayama M, Hashimoto T, Shigenobu K, Oha F, Ishida T, Yamane S (2003) Pitfalls of anterior cervical fusion using titanium mesh and local autograft. J Spinal Disord Tech 16: 513–518CrossRefPubMed Kanayama M, Hashimoto T, Shigenobu K, Oha F, Ishida T, Yamane S (2003) Pitfalls of anterior cervical fusion using titanium mesh and local autograft. J Spinal Disord Tech 16: 513–518CrossRefPubMed
43.
Zurück zum Zitat Kandziora F, Kerschbaumer F, Starker M, Mittlmeier T (2000) Biomechanical assessment of the transoral plate fixation for atlantoaxial instability. Spine 25: 1555–1561CrossRefPubMed Kandziora F, Kerschbaumer F, Starker M, Mittlmeier T (2000) Biomechanical assessment of the transoral plate fixation for atlantoaxial instability. Spine 25: 1555–1561CrossRefPubMed
44.
Zurück zum Zitat Kandziora F, Mittlmeier T, Kerschbaumer F (1999) Stage related surgery for cervical spine instability in rheumatoid arthritis. Eur Spine J 8: 371–381CrossRefPubMed Kandziora F, Mittlmeier T, Kerschbaumer F (1999) Stage related surgery for cervical spine instability in rheumatoid arthritis. Eur Spine J 8: 371–381CrossRefPubMed
45.
Zurück zum Zitat Kandziora F, Pflugmacher R, Schaefer J, Scholz M, Ludwig K, Schleicher P, Haas NP (2003) Biomechanical comparison of expandable cages for vertebral body replacement in the cervical spine. J Neurosurg 99 (Suppl): 91–97PubMed Kandziora F, Pflugmacher R, Schaefer J, Scholz M, Ludwig K, Schleicher P, Haas NP (2003) Biomechanical comparison of expandable cages for vertebral body replacement in the cervical spine. J Neurosurg 99 (Suppl): 91–97PubMed
46.
Zurück zum Zitat Kandziora F, Pflugmacher R, Schafer J, Born C, Duda G, Haas NP, Mittlmeier T (2001) Biomechanical comparison of cervical spine interbody fusion cages. Spine 26: 1850–1857CrossRefPubMed Kandziora F, Pflugmacher R, Schafer J, Born C, Duda G, Haas NP, Mittlmeier T (2001) Biomechanical comparison of cervical spine interbody fusion cages. Spine 26: 1850–1857CrossRefPubMed
47.
Zurück zum Zitat Kandziora F, Pflugmacher R, Scholz M, Schnake K, Schröder R, Mittlmeier T (2001) Comparison between sheep and human cervical spines: an anatomic, radiographic, bone mineral density, and biomechanical study. Spine 26: 1028–1037CrossRefPubMed Kandziora F, Pflugmacher R, Scholz M, Schnake K, Schröder R, Mittlmeier T (2001) Comparison between sheep and human cervical spines: an anatomic, radiographic, bone mineral density, and biomechanical study. Spine 26: 1028–1037CrossRefPubMed
48.
Zurück zum Zitat Kandziora F, Schollmeier G, Scholz M et al. (2002) Influence of cage design on interbody fusion in a sheep cervical spine model. J Neurosurg 96 (Suppl): 321–332PubMed Kandziora F, Schollmeier G, Scholz M et al. (2002) Influence of cage design on interbody fusion in a sheep cervical spine model. J Neurosurg 96 (Suppl): 321–332PubMed
49.
Zurück zum Zitat Kettler A, Wilke H, Dietl R, Krammer M, Lumenta C, Claes L (2000) Stabilising effect of posterior lumbar interbody fusion cages before and after cyclic loading. J Neurosurg (Spine 2) 92: 87–92 Kettler A, Wilke H, Dietl R, Krammer M, Lumenta C, Claes L (2000) Stabilising effect of posterior lumbar interbody fusion cages before and after cyclic loading. J Neurosurg (Spine 2) 92: 87–92
50.
Zurück zum Zitat Kinoshita A, Kataoka K, Taneda M (1999) Multilevel vertebral body replacement with a titanium mesh spacer for aneurysmal bone cyst: technical note. Minim Invasive Neurosurg 42: 156–158PubMed Kinoshita A, Kataoka K, Taneda M (1999) Multilevel vertebral body replacement with a titanium mesh spacer for aneurysmal bone cyst: technical note. Minim Invasive Neurosurg 42: 156–158PubMed
51.
Zurück zum Zitat Kirkpatrick JS, Levi J, Carillo J, Moeini SR (1999) Reconstruction after multilevel corpectomy in the cervical spine. A sagittal plane biomechanical study. Spine 24: 1186–1190CrossRefPubMed Kirkpatrick JS, Levi J, Carillo J, Moeini SR (1999) Reconstruction after multilevel corpectomy in the cervical spine. A sagittal plane biomechanical study. Spine 24: 1186–1190CrossRefPubMed
52.
Zurück zum Zitat Knop C, Bloth M, Buhren V et al. (2001) Surgical treatment of injuries of the thoracolumbar transition—3: Follow-up examination. Results of a prospective multi-center study by the „Spinal“ Study Group of the German Society of Trauma Surgery. Unfallchirurg 104: 583–600PubMed Knop C, Bloth M, Buhren V et al. (2001) Surgical treatment of injuries of the thoracolumbar transition—3: Follow-up examination. Results of a prospective multi-center study by the „Spinal“ Study Group of the German Society of Trauma Surgery. Unfallchirurg 104: 583–600PubMed
53.
Zurück zum Zitat Knop C, Lange U, Bastian L, Blauth M (2000) Three-dimensional motion analysis with Synex. Eur Spine J 9: 472–485CrossRefPubMed Knop C, Lange U, Bastian L, Blauth M (2000) Three-dimensional motion analysis with Synex. Eur Spine J 9: 472–485CrossRefPubMed
54.
Zurück zum Zitat Kumar A, Kurzak J, Doherty BJ, Dickson JH (1993) Interspace distraction and graft subsidence after anterior lumbar fusion with femoral strut allograft. Spine 18: 2393–2400PubMed Kumar A, Kurzak J, Doherty BJ, Dickson JH (1993) Interspace distraction and graft subsidence after anterior lumbar fusion with femoral strut allograft. Spine 18: 2393–2400PubMed
55.
Zurück zum Zitat Kurz M, Garfin S, Booth RE (1989) Harvesting autogenous iliac bone grafts. A review of complications and techniques. Spine 14: 1324–1331PubMed Kurz M, Garfin S, Booth RE (1989) Harvesting autogenous iliac bone grafts. A review of complications and techniques. Spine 14: 1324–1331PubMed
56.
Zurück zum Zitat Kuslich SD, Danielson G, Dowdle JD, Sherman J, Fredrickson B, Yuan H, Griffith SL (2000) Four-year follow-up results of lumbar spine arthrodesis using the Bagby and Kuslich lumbar fusion cage. Spine 25: 2656–2662CrossRefPubMed Kuslich SD, Danielson G, Dowdle JD, Sherman J, Fredrickson B, Yuan H, Griffith SL (2000) Four-year follow-up results of lumbar spine arthrodesis using the Bagby and Kuslich lumbar fusion cage. Spine 25: 2656–2662CrossRefPubMed
57.
Zurück zum Zitat Kuzhupilly RR, Lieberman I, McLain RF, Valdevit A, Kambic H, Richmond BJ (2002) In vitro stability of FRA spacers with integrated crossed screws for anterior lumbar interbody fusion. Spine 27: 923–928CrossRefPubMed Kuzhupilly RR, Lieberman I, McLain RF, Valdevit A, Kambic H, Richmond BJ (2002) In vitro stability of FRA spacers with integrated crossed screws for anterior lumbar interbody fusion. Spine 27: 923–928CrossRefPubMed
58.
Zurück zum Zitat Laing RJ, Ng I, Seeley HM, Hutchinson PJ (2001) Prospective study of clinical and radiographical outcome after anterior cervical discectomy. Br J Neurosurg 15: 319–323CrossRefPubMed Laing RJ, Ng I, Seeley HM, Hutchinson PJ (2001) Prospective study of clinical and radiographical outcome after anterior cervical discectomy. Br J Neurosurg 15: 319–323CrossRefPubMed
59.
Zurück zum Zitat Lange U, Knop C, Bastian L, Blauth M (2003) Prospective multicenter study with a new implant for thoracolumbar vertebral body replacement. Arch Orthop Trauma Surg 123: 203–208PubMed Lange U, Knop C, Bastian L, Blauth M (2003) Prospective multicenter study with a new implant for thoracolumbar vertebral body replacement. Arch Orthop Trauma Surg 123: 203–208PubMed
60.
Zurück zum Zitat Lee SW, Lin T, You JW, An HS (2000) Biomechanical effects of anterior grafting devices on the rotational stability of spinal constructs. J Spinal Disord 13: 150–155CrossRefPubMed Lee SW, Lin T, You JW, An HS (2000) Biomechanical effects of anterior grafting devices on the rotational stability of spinal constructs. J Spinal Disord 13: 150–155CrossRefPubMed
61.
Zurück zum Zitat Liljenqvist U, Lerner T, Bullmann V, Hackenberg L, Halm H, Winkelmann W (2003) Titanium cages in the surgical treatment of severe vertebral osteomyelitis. Eur Spine J 12: 606–612CrossRefPubMed Liljenqvist U, Lerner T, Bullmann V, Hackenberg L, Halm H, Winkelmann W (2003) Titanium cages in the surgical treatment of severe vertebral osteomyelitis. Eur Spine J 12: 606–612CrossRefPubMed
62.
Zurück zum Zitat Lin P (1985) Posterior lumbar interbody fusion technique: complications and pitfalls. Clin Orthop 193: 90–102PubMed Lin P (1985) Posterior lumbar interbody fusion technique: complications and pitfalls. Clin Orthop 193: 90–102PubMed
63.
Zurück zum Zitat Lowery GL, Harms J (1996) Titanium surgical mesh for vertebral defect replacement and intervertebral spacers. In: Thalgott JS, Aebi M (eds) Manual of internal fixation of the spine. Lippincott-Raven, Philadelphia, pp 127–146 Lowery GL, Harms J (1996) Titanium surgical mesh for vertebral defect replacement and intervertebral spacers. In: Thalgott JS, Aebi M (eds) Manual of internal fixation of the spine. Lippincott-Raven, Philadelphia, pp 127–146
64.
Zurück zum Zitat Lund T, Oxland T, Jost B, Cripton P, Grassmann S, Etter C, Nolte LP (1998) Interbody cage stabilisation in the lumbar spine: biomechanical evaluation of cage design, posterior instrumentation and bone density. J Bone Joint Surg Br 80: 351–359PubMed Lund T, Oxland T, Jost B, Cripton P, Grassmann S, Etter C, Nolte LP (1998) Interbody cage stabilisation in the lumbar spine: biomechanical evaluation of cage design, posterior instrumentation and bone density. J Bone Joint Surg Br 80: 351–359PubMed
65.
Zurück zum Zitat Main JA, Wells M, Spengler DM, Strauss AM, Keller TS (1989) Flexible device for vertebral body replacement. J Biomed Eng 11: 113–118PubMed Main JA, Wells M, Spengler DM, Strauss AM, Keller TS (1989) Flexible device for vertebral body replacement. J Biomed Eng 11: 113–118PubMed
66.
Zurück zum Zitat Majd ME, Vadhva M, Holt RT (1999) Anterior cervical reconstruction using titanium cages with anterior plating. Spine 24: 1604–1610CrossRefPubMed Majd ME, Vadhva M, Holt RT (1999) Anterior cervical reconstruction using titanium cages with anterior plating. Spine 24: 1604–1610CrossRefPubMed
67.
Zurück zum Zitat Martin GJ, Haid RJ, MacMillan M, Rodts GE, Berkman R (1999) Anterior cervical discectomy with freeze-dried fibula allograft. Overview of 317 cases and literature review. Spine 24: 852–858CrossRefPubMed Martin GJ, Haid RJ, MacMillan M, Rodts GE, Berkman R (1999) Anterior cervical discectomy with freeze-dried fibula allograft. Overview of 317 cases and literature review. Spine 24: 852–858CrossRefPubMed
68.
Zurück zum Zitat Matge G (1998) Anterior interbody fusion with the BAK-cage in cervical spondylosis. Acta Neurochir 140: 1–8CrossRef Matge G (1998) Anterior interbody fusion with the BAK-cage in cervical spondylosis. Acta Neurochir 140: 1–8CrossRef
69.
Zurück zum Zitat Munoz FLO, de las Heras B, Lopez VC, Siguero JJA (1998) Comparison of three techniques of anterior fusion in single-level cervical disc herniation. Eur Spine J 7: 512–516CrossRefPubMed Munoz FLO, de las Heras B, Lopez VC, Siguero JJA (1998) Comparison of three techniques of anterior fusion in single-level cervical disc herniation. Eur Spine J 7: 512–516CrossRefPubMed
70.
Zurück zum Zitat Narotam PK, Pauley S, McGinn GJ (2003) Titanium mesh cages for cervical spine stabilization after corpectomy: a clinical and radiological study. J Neurosurg 99 (Suppl): 172–180PubMed Narotam PK, Pauley S, McGinn GJ (2003) Titanium mesh cages for cervical spine stabilization after corpectomy: a clinical and radiological study. J Neurosurg 99 (Suppl): 172–180PubMed
71.
Zurück zum Zitat Nibu K, Panjabi M, Oxland T, Cholewicki J (1997) Multidirectional stabilising potential of BAK interbody spinal fusion system for anterior surgery. J Spinal Disord 10: 357–362PubMed Nibu K, Panjabi M, Oxland T, Cholewicki J (1997) Multidirectional stabilising potential of BAK interbody spinal fusion system for anterior surgery. J Spinal Disord 10: 357–362PubMed
72.
Zurück zum Zitat Okuyama K, Abe E, Chiba M, Ishikawa N, Sato K (1996) Outcome of anterior decompression and stabilization for thoracolumbar unstable burst fractures in the absence of neurologic deficits. Spine 21: 620–625CrossRefPubMed Okuyama K, Abe E, Chiba M, Ishikawa N, Sato K (1996) Outcome of anterior decompression and stabilization for thoracolumbar unstable burst fractures in the absence of neurologic deficits. Spine 21: 620–625CrossRefPubMed
73.
Zurück zum Zitat Oxland TR, Hoffer Z, Nydegger T, Rathonyi GC, Nolte LP (2000) A comparative biomechanical investigation of anterior lumbar interbody cages: central and bilateral approaches. J Bone Joint Surg Am 82: 383–393PubMed Oxland TR, Hoffer Z, Nydegger T, Rathonyi GC, Nolte LP (2000) A comparative biomechanical investigation of anterior lumbar interbody cages: central and bilateral approaches. J Bone Joint Surg Am 82: 383–393PubMed
74.
Zurück zum Zitat Parthiban JK, Singhania B, Ramani PS (2002) A radiological evaluation of allografts (ethylene oxide sterilized cadaver bone) and autografts in anterior cervical fusion. Neurol India 50: 17–22PubMed Parthiban JK, Singhania B, Ramani PS (2002) A radiological evaluation of allografts (ethylene oxide sterilized cadaver bone) and autografts in anterior cervical fusion. Neurol India 50: 17–22PubMed
75.
Zurück zum Zitat Perrin RG, McBroom R, Perrin RG (1991) Metastatic tumors of the cervical spine. Clin Neurosurg 37: 740–755PubMed Perrin RG, McBroom R, Perrin RG (1991) Metastatic tumors of the cervical spine. Clin Neurosurg 37: 740–755PubMed
76.
Zurück zum Zitat Profeta G, de Falco R, Ianniciello G, Profeta L, Cigliano A, Raja AI (2000) Preliminary experience with anterior cervical microdiscetomy and interbody titanium cage fusion (Novus CT-Ti) in patients with cervical disc disease. Surg Neurol 53: 417–426 Profeta G, de Falco R, Ianniciello G, Profeta L, Cigliano A, Raja AI (2000) Preliminary experience with anterior cervical microdiscetomy and interbody titanium cage fusion (Novus CT-Ti) in patients with cervical disc disease. Surg Neurol 53: 417–426
77.
Zurück zum Zitat Rapoff AJ, Ghanayem. A, Zdeblick TA (1997) Biomechanical comparison of posterior lumbar interbody fusion cages. Spine 22: 2375–2379CrossRefPubMed Rapoff AJ, Ghanayem. A, Zdeblick TA (1997) Biomechanical comparison of posterior lumbar interbody fusion cages. Spine 22: 2375–2379CrossRefPubMed
78.
Zurück zum Zitat Robertson PA, Rawlinson H, Hadlow AT (2004) Radiologic stability of titanium mesh cages for anterior spinal reconstruction following thoracolumbar corpectomy. J Spinal Disord Tech 17: 44–52CrossRefPubMed Robertson PA, Rawlinson H, Hadlow AT (2004) Radiologic stability of titanium mesh cages for anterior spinal reconstruction following thoracolumbar corpectomy. J Spinal Disord Tech 17: 44–52CrossRefPubMed
79.
Zurück zum Zitat Robinson RA (1964) Anterior and posterior cervical spine fusions. Clin Orthop 35: 34–36PubMed Robinson RA (1964) Anterior and posterior cervical spine fusions. Clin Orthop 35: 34–36PubMed
80.
Zurück zum Zitat Rohlmann A, Zander T, Fehrmann M, Klöckner C, Bergmann G (2002) Influence of implants for vertebral body replacement on the mechanical behavior of the lumbar spine. Orthopäde 31: 503–507 Rohlmann A, Zander T, Fehrmann M, Klöckner C, Bergmann G (2002) Influence of implants for vertebral body replacement on the mechanical behavior of the lumbar spine. Orthopäde 31: 503–507
81.
Zurück zum Zitat Sack S (1966) Anterior interbody fusion of the lumbar spine. Indications and results in 200 cases. Clin Orthop 44: 163–170PubMed Sack S (1966) Anterior interbody fusion of the lumbar spine. Indications and results in 200 cases. Clin Orthop 44: 163–170PubMed
82.
Zurück zum Zitat Sandhu HS, Turner S, Kabo M et al. (1996) Distractive properties of threaded interbody fusion device. An in vivo model. Spine 21: 1201–1210CrossRefPubMed Sandhu HS, Turner S, Kabo M et al. (1996) Distractive properties of threaded interbody fusion device. An in vivo model. Spine 21: 1201–1210CrossRefPubMed
83.
Zurück zum Zitat Schnee CL, Freese A, Weil RJ, Marcotte PJ (1997) Analysis of harvest morbidity and radiographic outcome using autograft for anterior cervical fusion. Spine 22: 2222–2227CrossRefPubMed Schnee CL, Freese A, Weil RJ, Marcotte PJ (1997) Analysis of harvest morbidity and radiographic outcome using autograft for anterior cervical fusion. Spine 22: 2222–2227CrossRefPubMed
84.
Zurück zum Zitat Schultz KD, McLaughlin M, Haid RW, Comey CH, Rodts GE, Alexander J (2000) Single-stage anterior-posterior decompression and stabilization for complex cervical spine disorders. J Neurosurg 93 (Suppl): 214–221 Schultz KD, McLaughlin M, Haid RW, Comey CH, Rodts GE, Alexander J (2000) Single-stage anterior-posterior decompression and stabilization for complex cervical spine disorders. J Neurosurg 93 (Suppl): 214–221
85.
Zurück zum Zitat Shimamoto N, Cunningham B, Dmitriev AE, Minami A, McAfee PC (2001) Biomechanical evaluation of stand-alone interbody fusion cages in the cervical spine. Spine 26: 432–436CrossRef Shimamoto N, Cunningham B, Dmitriev AE, Minami A, McAfee PC (2001) Biomechanical evaluation of stand-alone interbody fusion cages in the cervical spine. Spine 26: 432–436CrossRef
86.
Zurück zum Zitat Siqueira EB, Kranzler L (1983) Replacement of cervical vertebral body with a tibial bone graft. South Med J 76: 607–609PubMed Siqueira EB, Kranzler L (1983) Replacement of cervical vertebral body with a tibial bone graft. South Med J 76: 607–609PubMed
87.
Zurück zum Zitat Solini A, Orsini G, Broggi S (1989) Metal cementless prosthesis for vertebral body replacement of metastatic malignant disease of the cervical spine. J Spinal Disord Tech 2: 254–262 Solini A, Orsini G, Broggi S (1989) Metal cementless prosthesis for vertebral body replacement of metastatic malignant disease of the cervical spine. J Spinal Disord Tech 2: 254–262
88.
Zurück zum Zitat Spivak JM, Bharam S, Chen D, Kummer FJ (2000) Internal fixation of cervical trauma following corpectomy and reconstruction. The effects of posterior element injury. Bull Hosp Jt Dis 59: 47–51PubMed Spivak JM, Bharam S, Chen D, Kummer FJ (2000) Internal fixation of cervical trauma following corpectomy and reconstruction. The effects of posterior element injury. Bull Hosp Jt Dis 59: 47–51PubMed
89.
Zurück zum Zitat Stauffer RN, Conventry M (1972) Anterior interbody lumbar spine fusion: Analysis of Mayo Clinics series. J Bone Joint Surg Am 54: 756PubMed Stauffer RN, Conventry M (1972) Anterior interbody lumbar spine fusion: Analysis of Mayo Clinics series. J Bone Joint Surg Am 54: 756PubMed
90.
Zurück zum Zitat Stoltze D, Harm J (1999) Correction of posttraumatic deformities. Principles and methods. Orthopäde 28: 731–745 Stoltze D, Harm J (1999) Correction of posttraumatic deformities. Principles and methods. Orthopäde 28: 731–745
91.
Zurück zum Zitat Svendgaard NA, Cronqist S, Delgado T, Salford LG (1982) Treatment of severe cervical spine injuries by anterior interbody fusion with early mobilization. Acta Neurochir 60: 91–105 Svendgaard NA, Cronqist S, Delgado T, Salford LG (1982) Treatment of severe cervical spine injuries by anterior interbody fusion with early mobilization. Acta Neurochir 60: 91–105
92.
Zurück zum Zitat Tencer AF, Hampton D, Eddy S (1995) Biomechanical properties of threaded inserts for lumbar interbody spinal fusion. Spine 20: 2408–2414PubMed Tencer AF, Hampton D, Eddy S (1995) Biomechanical properties of threaded inserts for lumbar interbody spinal fusion. Spine 20: 2408–2414PubMed
93.
Zurück zum Zitat Thalgott JS, Xiongsheng C, Giuffre JM (2003) Single stage anterior cervical reconstruction with titanium mesh cages, local bone graft, and anterior plating. Spine J 3: 294–300CrossRefPubMed Thalgott JS, Xiongsheng C, Giuffre JM (2003) Single stage anterior cervical reconstruction with titanium mesh cages, local bone graft, and anterior plating. Spine J 3: 294–300CrossRefPubMed
94.
Zurück zum Zitat Togawa D, Bauer T, Brantigan JW, Lowery GL (2001) Bone graft incorporation in radiographically successful human intervertebral body fusion cages. Spine 26: 2744–2750CrossRefPubMed Togawa D, Bauer T, Brantigan JW, Lowery GL (2001) Bone graft incorporation in radiographically successful human intervertebral body fusion cages. Spine 26: 2744–2750CrossRefPubMed
95.
Zurück zum Zitat Tomita K, Kawahara N, Kobayashi T, Yoshida A, Murakami H, Akamaru I, Tomoyuki (2001) Surgical strategy for spinal metastases. Spine 26: 298–306CrossRefPubMed Tomita K, Kawahara N, Kobayashi T, Yoshida A, Murakami H, Akamaru I, Tomoyuki (2001) Surgical strategy for spinal metastases. Spine 26: 298–306CrossRefPubMed
96.
Zurück zum Zitat Vahldiek MJ, Panjabi M (1998) Stability potential of spinal instrumentations in tumor vertebral body replacement surgery. Spine 23: 543–550CrossRefPubMed Vahldiek MJ, Panjabi M (1998) Stability potential of spinal instrumentations in tumor vertebral body replacement surgery. Spine 23: 543–550CrossRefPubMed
97.
Zurück zum Zitat Vanden Berghe L, Mehdian H, Lee AJ (1993) Stability of the lumbar spine and method of instrumentation. Acta Orthop Belg 59: 175–180PubMed Vanden Berghe L, Mehdian H, Lee AJ (1993) Stability of the lumbar spine and method of instrumentation. Acta Orthop Belg 59: 175–180PubMed
98.
Zurück zum Zitat Vavruch L, Hedlund R, Javid D, Leszniewski W, Shalabi A (2002) A prospective randomised comparison between the Cloward procedure and a carbon fiber cage in the cervical spine. A clinical and radiologic study. Spine 27: 1694–1701CrossRefPubMed Vavruch L, Hedlund R, Javid D, Leszniewski W, Shalabi A (2002) A prospective randomised comparison between the Cloward procedure and a carbon fiber cage in the cervical spine. A clinical and radiologic study. Spine 27: 1694–1701CrossRefPubMed
99.
Zurück zum Zitat Vieweg U, Kaden B, Schramm J (1996) Vertebral body replacement with a rib segment block in transthoracic intervention. Zentralbl Neurochir 57: 136–142PubMed Vieweg U, Kaden B, Schramm J (1996) Vertebral body replacement with a rib segment block in transthoracic intervention. Zentralbl Neurochir 57: 136–142PubMed
100.
Zurück zum Zitat Vieweg U, Meyer B, Schramm J (2001) Tumour surgery of the upper cervical spine--a retrospective study of 13 cases. Acta Neurochir 143: 217–225CrossRef Vieweg U, Meyer B, Schramm J (2001) Tumour surgery of the upper cervical spine--a retrospective study of 13 cases. Acta Neurochir 143: 217–225CrossRef
101.
Zurück zum Zitat Weiner BK, Fraser R (1998) Spine update lumbar interbody fusion cages. Spine 23: 634–640PubMed Weiner BK, Fraser R (1998) Spine update lumbar interbody fusion cages. Spine 23: 634–640PubMed
102.
Zurück zum Zitat Wilke HJ, Kettler A, Claes L (2000) Primary stabilizing effect of interbody fusion devices for the cervical spine: an in vitro comparison between three different cage types and bone cement. Eur Spine J 9: 410–416CrossRefPubMed Wilke HJ, Kettler A, Claes L (2000) Primary stabilizing effect of interbody fusion devices for the cervical spine: an in vitro comparison between three different cage types and bone cement. Eur Spine J 9: 410–416CrossRefPubMed
103.
Zurück zum Zitat Wilke HJ, Wenger K, Claes L (1998) Testing criteria for spinal implants: recommendations for the standardization of in vitro stability testing of spinal implants. Eur Spine J 7: 148–154PubMed Wilke HJ, Wenger K, Claes L (1998) Testing criteria for spinal implants: recommendations for the standardization of in vitro stability testing of spinal implants. Eur Spine J 7: 148–154PubMed
104.
Zurück zum Zitat Wittenberg RH, Moeller J, Shea M, White AA, Hayes WC (1990) Compressive strength of autologous and allogenous bone grafts for thoracolumbar and cervical spine fusion. Spine 15: 1073–1078PubMed Wittenberg RH, Moeller J, Shea M, White AA, Hayes WC (1990) Compressive strength of autologous and allogenous bone grafts for thoracolumbar and cervical spine fusion. Spine 15: 1073–1078PubMed
105.
Zurück zum Zitat Younger EM, Chapman. M (1989) Morbidity at bone graft donor sites. J Orthop Trauma 3: 192–195PubMed Younger EM, Chapman. M (1989) Morbidity at bone graft donor sites. J Orthop Trauma 3: 192–195PubMed
Metadaten
Titel
Wirbelkörperersatz in der Wirbelsäulenchirurgie
verfasst von
Priv.-Doz. Dr. F. Kandziora
K. J. Schnake
C. K. Klostermann
N. P. Haas
Publikationsdatum
01.05.2004
Verlag
Springer-Verlag
Erschienen in
Die Unfallchirurgie / Ausgabe 5/2004
Print ISSN: 2731-7021
Elektronische ISSN: 2731-703X
DOI
https://doi.org/10.1007/s00113-004-0777-z

Weitere Artikel der Ausgabe 5/2004

Der Unfallchirurg 5/2004 Zur Ausgabe

Für Sie gelesen—Evidenzbasierte Unfallchirurgie

Klinische Studien in der Unfallchirurgie

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

26.04.2024 Hüft-TEP Nachrichten

Ob bei einer Notfalloperation nach Schenkelhalsfraktur eine Hemiarthroplastik oder eine totale Endoprothese (TEP) eingebaut wird, sollte nicht allein vom Alter der Patientinnen und Patienten abhängen. Auch über 90-Jährige können von der TEP profitieren.

Arthroskopie kann Knieprothese nicht hinauszögern

25.04.2024 Gonarthrose Nachrichten

Ein arthroskopischer Eingriff bei Kniearthrose macht im Hinblick darauf, ob und wann ein Gelenkersatz fällig wird, offenbar keinen Unterschied.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Ärztliche Empathie hilft gegen Rückenschmerzen

23.04.2024 Leitsymptom Rückenschmerzen Nachrichten

Personen mit chronischen Rückenschmerzen, die von einfühlsamen Ärzten und Ärztinnen betreut werden, berichten über weniger Beschwerden und eine bessere Lebensqualität.

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.