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European Journal of Nutrition

Erschienen in:

13.07.2020 | Letter to the Editor

Within-group comparisons led to unsubstantiated conclusions in “Low-phytate wholegrain bread instead of high-phytate wholegrain bread in a total diet context did not improve iron status of healthy Swedish females: a 12-week, randomized, parallel-design intervention Study”

verfasst von: Colby J. Vorland, Luis M. Mestre, Sachintha S. Mendis, Andrew W. Brown

Erschienen in: European Journal of Nutrition | Ausgabe 6/2020

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Excerpt

Hoppe et al. recently published a study examining the effect of high and low phytate intake on iron status in a free-living population over 12 weeks [1], an important question in light of existing controlled feeding studies that were much more acute. However, we have concerns about the statistical analyses and interpretation that warrant a re-evaluation of the conclusions. …

Hoppe M, Ross AB, Svelander C, Sandberg A-S, Hulthén L (2019) Low-phytate wholegrain bread instead of high-phytate wholegrain bread in a total diet context did not improve iron status of healthy Swedish females: a 12-week, randomized, parallel-design intervention study. Eur J Nutr 58(2):853–864CrossRef

Allison DB, Brown AW, George BJ, Kaiser KA (2016) Reproducibility: a tragedy of errors. Nature 530(7588):27–29CrossRef

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Bland JM, Altman DG (2015) Best (but oft forgotten) practices: testing for treatment effects in randomized trials by separate analyses of changes from baseline in each group is a misleading approach. Am J Clin Nutr 102(5):991–994CrossRef

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Titel: Within-group comparisons led to unsubstantiated conclusions in “Low-phytate wholegrain bread instead of high-phytate wholegrain bread in a total diet context did not improve iron status of healthy Swedish females: a 12-week, randomized, parallel-design intervention Study”
verfasst von: Colby J. Vorland
Luis M. Mestre
Sachintha S. Mendis
Andrew W. Brown
Publikationsdatum: 13.07.2020
Verlag: Springer Berlin Heidelberg
Erschienen in: European Journal of Nutrition / Ausgabe 6/2020
Print ISSN: 1436-6207
Elektronische ISSN: 1436-6215
DOI: https://doi.org/10.1007/s00394-020-02287-0

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Within-group comparisons led to unsubstantiated conclusions in “Low-phytate wholegrain bread instead of high-phytate wholegrain bread in a total diet context did not improve iron status of healthy Swedish females: a 12-week, randomized, parallel-design intervention Study”

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