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01.12.2012 | Case report | Ausgabe 1/2012 Open Access

World Journal of Surgical Oncology 1/2012

Xanthogranulomatous inflammation involving latissimus dorsi donor site and implant breast reconstruction: case report and literature review

World Journal of Surgical Oncology > Ausgabe 1/2012
Tasadooq Hussain, Bilal Elahi, Ervine Long, Tapan Mahapatra, Penelope L McManus, Peter J Kneeshaw
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​1477-7819-10-166) contains supplementary material, which is available to authorized users.

Competing interests

The authors report that they have no conflict of interests.

Authors’ contributions

TH did the literature search and has been a major contributor in writing the manuscript. PJK did the final draft proof reading and approval. EL provided the pathology images. All authors read and approved the final manuscript.


Xanthogranulomatous inflammation is a rare clinico-pathological condition involving many organ systems. Breast involvement with this rare condition reported from a few cases of mastitis has been limited to only microscopic involvement on histology. We would like to report an unusual presentation of this inflammatory process presenting as a solid lump mimicking malignancy in latissimus dorsi donor site scar and implant-based breast reconstruction as a result of a ruptured silicone gel implant. To our knowledge there have been no previous reports on similar presentation published in the literature. This case highlights a rare complication of a leaked silicone gel implant triggering a xanthomatous response in the absence of the usual infective or obstructing etiologies. This condition is of benign nature with complete clearance on surgical excision and excellent clinical prognosis reported from other organ involvement.
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