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Current Osteoporosis Reports
Erschienen in: Current Osteoporosis Reports 6/2016

28.10.2016 | Muscle and Bone (L Bonewald and M Hamrick, Section Editors)

A Comparison of Peripheral Imaging Technologies for Bone and Muscle Quantification: a Mixed Methods Clinical Review

verfasst von: Andy Kin On Wong

Erschienen in: Current Osteoporosis Reports | Ausgabe 6/2016

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Abstract

Purpose of Review

Bone and muscle peripheral imaging technologies are reviewed for their association with fractures and frailty. A narrative systematized review was conducted for bone and muscle parameters from each imaging technique. In addition, meta-analyses were performed across all bone quality parameters.

Recent Findings

The current body of evidence for bone quality’s association with fractures is strong for (high-resolution) peripheral quantitative computed tomography (pQCT), with trabecular separation (Tb.Sp) and integral volumetric bone mineral density (vBMD) reporting consistently large associations with various fracture types across studies. Muscle has recently been linked to fractures and frailty, but the quality of evidence remains weaker from studies of small sample sizes.

Summary

It is increasingly apparent that musculoskeletal tissues have a complex relationship with interrelated clinical endpoints such as fractures and frailty. Future studies must concurrently address these relationships in order to decipher the relative importance of one causal pathway from another.
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Metadaten
Titel
A Comparison of Peripheral Imaging Technologies for Bone and Muscle Quantification: a Mixed Methods Clinical Review
verfasst von
Andy Kin On Wong
Publikationsdatum
28.10.2016
Verlag
Springer US
Erschienen in
Current Osteoporosis Reports / Ausgabe 6/2016
Print ISSN: 1544-1873
Elektronische ISSN: 1544-2241
DOI
https://doi.org/10.1007/s11914-016-0334-z

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