Background
Method
CSAW Cohort
Image Annotation
CSAW Case-Control Subset
Results
Cancer status | Women | % |
---|---|---|
Total | 499,807 | 100.0% |
Healthy (at least until Dec. 31, 2015) | 489,225 | 97.5% |
Diagnosed with cancer | 10,582 | 2.1% |
Prior cancer or age outside screening range | 2119 | 0.4% |
Incident cancer (2008 to 2015) | 8463 | 1.7% |
Invitation to screening | Completed examination | |||
---|---|---|---|---|
n | % | n | % | |
Karolinska University Hospital | 278,996 | 17% | 198,820 | 17% |
Sankt G8ran Hospital | 668,366 | 40% | 454,341 | 38% |
Southern General Hospital | 482,883 | 29% | 340,866 | 29% |
Danderyd Hospital | 257,717 | 15% | 188,527 | 16% |
Other | 254 | < 1% | 179 | < 1% |
Total | 1,688,216 | 100% | 1,182,733 | 100% |
Women with prior cancer were not included | ||
---|---|---|
Parameter | n | % |
Age at breast cancer diagnosis (years) | ||
40 to 49 | 1927 | 23% |
50 to 59 | 2379 | 28% |
60 to 69 | 3227 | 38% |
70+ | 930 | 11% |
Missing information | 0 | 0% |
Detection mode | ||
Screen-detected cancer | 4703 | 56% |
Interval cancer (2-year interval) | 1938 | 23% |
Overdue > 3 years | 393 | 5% |
Never-screened | 566 | 7% |
Indeterminate detection mode | 863 | 10% |
Missing information | 0 | 0% |
Tumor size | ||
0–5 mm | 278 | 3% |
6–10 mm | 1263 | 15% |
11–19 mm | 3014 | 36% |
20+ mm | 2476 | 29% |
Missing information | 1432 | 17% |
Invasiveness | ||
Invasive only | 3130 | 37% |
In situ only | 1080 | 13% |
Mixed invasive and in situ | 4117 | 49% |
Missing information | 136 | 2% |
Lymph node status | ||
Negative, no metastasis | 7572 | 89% |
Positive, metastasis detected | 876 | 10% |
Missing information | 15 | 0% |
Histology | ||
Ductal only | 5632 | 67% |
Lobular only | 922 | 11% |
Medullary | 43 | 1% |
Mixed or other | 623 | 7% |
Missing information or in situ cancer | 1243 | 15% |
Receptor status | ||
Estrogen receptor positive | 6599 | 78% |
Estrogen receptor negative | 911 | 11% |
Missing information | 953 | 11% |
Progesterone receptor positive | 5527 | 65% |
Progesterone receptor negative | 1855 | 22% |
Missing information | 1081 | 13% |
HER2 receptor amplified | 902 | 11% |
HER2 receptor negative | 5463 | 65% |
Missing information | 2098 | 25% |
Annotation type | Women | Images | |
---|---|---|---|
Tumor annotated, total | 898 | 1891 | |
Tumor annotated, at diagnosis | 896 | 1761 | |
Tumor annotated, at prior screening | 72 | 139 | |
Location defined, no tumor, at prior screening | 177 | 335 | |
Annotation measure | 25%-tile | Median | 75%-tile |
Area (pixels2), at diagnosis (n = 1741) | 15,780 | 32,906 | 72,383 |
Area (pixels2), at prior screening (n = 130) | 3573 | 7027 | 11,773 |
Major axis (pixels), at diagnosis (n = 1741) | 177 | 258 | 396 |
Major axis (pixels), at prior screening (n = 130) | 83 | 118 | 163 |