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European Journal of Nutrition

Erschienen in:

01.03.2014 | Original Contribution

Acute effects of high-protein versus normal-protein isocaloric meals on satiety and ghrelin

verfasst von: Dan Yang, Zhihong Liu, Haixing Yang, Ye Jue

Erschienen in: European Journal of Nutrition | Ausgabe 2/2014

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Abstract

Purpose

The objective was to compare isocaloric high-protein (HP) test meals with normal-protein (NP) test ones on satiety and ghrelin in human being.

Methods

Systematic searches were conducted by using PubMed, Cochrane library, EMBASE, and HighWire Press to identify randomized, crossover trials that investigated the acute effects of isocalorically prescribed HP versus NP test meals on satiety and ghrelin.

Results

Pooled analyses showed that subjects with HP test meals had a significantly higher acute satiety area under the curve (AUC) than those with NP test meals (P < 0.001). Conversely, the former had a markedly lower level of acute ghrelin at 180 min as well as acute glucose AUC, although they had a notably higher glucose at 180 min (P = 0.008).

Conclusions

The meta-analysis showed that the acute consumption of HP did produce more satiety. In addition, relative to NP test meals, HP test ones may be useful in regulating postprandial glucose, whereas a significantly higher preprandial glucose combined with a lower concentration of ghrelin may contribute to the decrease in ad libitum caloric intake.

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Titel: Acute effects of high-protein versus normal-protein isocaloric meals on satiety and ghrelin
verfasst von: Dan Yang
Zhihong Liu
Haixing Yang
Ye Jue
Publikationsdatum: 01.03.2014
Verlag: Springer Berlin Heidelberg
Erschienen in: European Journal of Nutrition / Ausgabe 2/2014
Print ISSN: 1436-6207
Elektronische ISSN: 1436-6215
DOI: https://doi.org/10.1007/s00394-013-0552-4

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