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Pediatric Nephrology
Erschienen in: Pediatric Nephrology 10/2021

07.01.2021 | Review

Acute kidney injury and aging

verfasst von: Monica Chang-Panesso

Erschienen in: Pediatric Nephrology | Ausgabe 10/2021

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Abstract

Our aging population is growing and developing treatments for age-related diseases such as Alzheimer’s and Parkinson’s disease has taken on an increasing urgency and is accompanied by high public awareness. The already high and rising incidence of acute kidney injury (AKI) in the elderly, however, has received relatively little attention despite the potentially fatal outcomes associated with an episode of AKI in this age group. When discussing AKI and aging, one should consider two aspects: first, elderly patients have an increased susceptibility to an AKI episode, and second, they have decreased kidney repair after AKI given the high incidence of progression to chronic kidney disease (CKD). It is unclear if the same factors that drive the increased susceptibility to AKI could be playing a role in the decreased repair capacity or if they are totally different and unrelated. This review will examine current knowledge on the risk factors for the increased susceptibility to AKI in the elderly and will also explore potential aspects that might contribute to a decreased kidney repair response in this age group.
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Metadaten
Titel
Acute kidney injury and aging
verfasst von
Monica Chang-Panesso
Publikationsdatum
07.01.2021
Verlag
Springer Berlin Heidelberg
Erschienen in
Pediatric Nephrology / Ausgabe 10/2021
Print ISSN: 0931-041X
Elektronische ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-020-04849-0

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