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Journal of Anesthesia

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01.02.2012 | Clinical Report

Additive diuretic response of concurrent aminophylline and furosemide in children: a case series and a brief literature review

verfasst von: Paulo Sérgio Lucas da Silva, Vânia Euzébio de Aguiar, Marcelo Cunio Machado Fonseca

Erschienen in: Journal of Anesthesia | Ausgabe 1/2012

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Abstract

Aminophylline exerts a renovascular effect, acting by adenosine receptor blockade or type IV phosphodiesterase inhibition. Clinically, these drugs have been used with furosemide to induce diuresis in adults and neonates. However, reports on use of aminophylline in diuretic-dependent children are limited to a few studies. We report a case series of four critically ill children unresponsive to furosemide continuous infusion who were subsequently given aminophylline as an adjunct diuretic in the treatment of fluid overload. No side effects were evident. Administration of aminophylline at low doses (3 mg/kg) successfully promoted increased urine output over the 6-h study period in all four children.

Simmons RS, Berdine GG, Seidenfeld JJ, Prihoda TJ, Harris GD, Smith JD, Gilbert TJ, Mota E, Johanson WG Jr. Fluid balance and the adult respiratory distress syndrome. Am Rev Respir Dis. 1987;135:924–9.CrossRefPubMed

Carcillo JA, Fields AI. Clinical practice parameters for hemodynamic support of pediatric and neonatal patients in septic shock. Crit Care Med. 2002;30:1365–78.CrossRefPubMed

Hoste EA, Kellum JA. Acute renal failure in the critically ill: impact on morbidity and mortality. Contrib Nephrol. 2004;144:1–11.CrossRefPubMed

Bagshaw SM, Bellomo R, Kellum JA. Oliguria, volume overload, and loop diuretics. Crit Care Med. 2008;36:S172–8.CrossRefPubMed

Sakr Y, Vincent JL, Reinhart K, Groeneveld J, Michalopoulos A, Sprung CL, Artigas A, Ranieri VM. High tidal volume and positive fluid balance are associated with worse outcome in acute lung injury. Chest. 2005;128:3098–108.CrossRefPubMed

Kelly RE Jr, Phillips JD, Foglia RP, Bjerke HS, Barcliff LT, Petrus L, Hall TR. Pulmonary edema and fluid mobilization as determinants of the duration of ECMO support. J Pediatr Surg. 1991;26:1016–22.CrossRefPubMed

Mitchell JP, Schuller D, Calandrino FS, Schuster DP. Improved outcome based on fluid management in critically ill patients requiring pulmonary artery catheterization. Am Rev Respir Dis. 1992;145:990–8.CrossRefPubMed

National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network, Wiedemann HP, Wheeler AP, Bernard GR, Thompson BT, Hayden D, deBoisblanc B, Connors AF Jr, Hite RD, Harabin AL. Comparison of two fluid-management strategies in acute lung injury. N Engl J Med. 2006;354:2564–75.CrossRef

Ware LB, Matthay MA. Alveolar fluid clearance is impaired in the majority of patients with acute lung injury and the acute respiratory distress syndrome. Am J Respir Crit Care Med. 2001;163:1376–83.CrossRefPubMed

10.

Foland JA, Fortenberry JD, Warshaw BL, Pettignano R, Merritt RK, Heard ML, Rogers K, Reid C, Tanner AJ, Easley KA. Fluid overload before continuous hemofiltration and survival in critically ill children: a retrospective analysis. Crit Care Med. 2004;32:1771–6.CrossRefPubMed

11.

Heiss KF, Pettit B, Hirschl RB, Cilley RE, Chapman R, Bartlett RH. Renal insufficiency and volume overload in neonatal ECMO managed by continuous ultrafiltration. ASAIO Trans. 1987;33:557–60.PubMed

12.

Roy BJ, Cornish JD, Clark RH. Venovenous extracorporeal membrane oxygenation affects renal function. Pediatrics. 1995;95:573–8.PubMed

13.

Rosenberg AL. Fluid management in patients with acute respiratory distress syndrome. Respir Care Clin N Am. 2003;9:481–93.CrossRefPubMed

14.

Klinge JM, Scharf J, Hofbeck M, Gerling S, Bonakdar S, Singer H. Intermittent administration of furosemide versus continuous infusion in the postoperative management of children following open heart surgery. Intensive Care Med. 1997;23:693–7.CrossRefPubMed

15.

Ng GY, Baker EH, Farrer KF. Aminophylline as an adjunct diuretic for neonates: a case series. Pediatr Nephrol. 2005;20:220–2.CrossRefPubMed

16.

Noguchi T, Hayano Y, Iwasaka H, Setoguchi K, Oda S, Taniguchi K, Honda N, Mori Y, Hadama T. Diuretic effects of aminophylline in patients after cardiac surgery. Masui (Jpn J Anesthesiol). 1990;39:1002–6. (in Japanese with English abstract).

17.

Brater DC, Kaojarern S, Chennavasin P. Pharmacodynamics of the diuretic effects of aminophylline and acetazolamide alone and combined with furosemide in normal subjects. J Pharmacol Exp Ther. 1983;227:92–7.PubMed

18.

Harkavy KL, Scanlon JW, Jose P. The effects of theophylline on renal function in the premature newborn. Biol Neonate. 1979;35:126–30.CrossRefPubMed

19.

Jenik AG, Ceriani Cernadas JM, Gorenstein A, Ramirez JA, Vain N, Armadans M, Ferraris JR. A randomized, double-blind, placebo-controlled trial of the effects of prophylactic theophylline on renal function in term neonates with perinatal asphyxia. Pediatrics. 2000;105:E45.CrossRefPubMed

20.

Bakr AF. Prophylactic theophylline to prevent renal dysfunction in newborns exposed to perinatal asphyxia—a study in a developing country. Pediatr Nephrol. 2005;20:1249–52.CrossRefPubMed

21.

McLaughlin GE, Land MP, Rossique-Gonzalez M. Effect of aminophylline on urine flow in children with tacrolimus-induced renal insufficiency. Transpl Proc. 2000;32:817–20.CrossRef

22.

McLaughlin GE, Abitbol CL. Reversal of oliguric tacrolimus nephrotoxicity in children. Nephrol Dial Transpl. 2005;20:1471–5.CrossRef

23.

Mazkereth R, Laufer J, Jordan S, Pomerance JJ, Boichis H, Reichman B. Effects of theophylline on renal function in premature infants. Am J Perinatol. 1997;14:45–9.CrossRefPubMed

24.

Lochan SR, Adeniyi-Jones S, Assadi FK, Frey BM, Marcus S, Baumgart S. Coadministration of theophylline enhances diuretic response to furosemide in infants during extracorporeal membrane oxygenation: a randomized controlled pilot study. J Pediatr. 1998;133:86–9.CrossRefPubMed

25.

Bell M, Jackson E, Mi Z, McCombs J, Carcillo J. Low-dose theophylline increases urine output in diuretic-dependent critically ill children. Intensive Care Med. 1998;24:1099–105.CrossRefPubMed

26.

Bhat MA, Shah ZA, Makhdoomi MS, Mufti MH. Theophylline for renal function in term neonates with perinatal asphyxia: a randomized, placebo-controlled trial. J Pediatr. 2006;149:180–4.CrossRefPubMed

27.

Huet F, Semama D, Grimaldi M, Guignard JP, Gouyon JB. Effects of theophylline on renal insufficiency in neonates with respiratory distress syndrome. Intensive Care Med. 1995;21:511–4.CrossRefPubMed

28.

Pretzlaff RK, Vardis RJ, Pollack MM. Aminophylline in the treatment of fluid overload. Crit Care Med. 1999;27:2782–5.CrossRefPubMed

29.

Cattarelli D, Spandrio M, Gasparoni A, Bottino R, Offer C, Chirico G. A randomised, double blind, placebo controlled trial of the effect of theophylline in prevention of vasomotor nephropathy in very preterm neonates with respiratory distress syndrome. Arch Dis Child Fetal Neonatal Ed. 2006;91:F80–4.CrossRefPubMedPubMedCentral

30.

Givertz MM, Massie BM, Fields TK, Pearson LL, Dittrich HC. The effects of KW-3902, an adenosine A1-receptor antagonist, on diuresis and renal function in patients with acute decompensated heart failure and renal impairment or diuretic resistance. J Am Coll Cardiol. 2007;50:1551–60.CrossRefPubMed

Titel: Additive diuretic response of concurrent aminophylline and furosemide in children: a case series and a brief literature review
verfasst von: Paulo Sérgio Lucas da Silva
Vânia Euzébio de Aguiar
Marcelo Cunio Machado Fonseca
Publikationsdatum: 01.02.2012
Verlag: Springer Japan
Erschienen in: Journal of Anesthesia / Ausgabe 1/2012
Print ISSN: 0913-8668
Elektronische ISSN: 1438-8359
DOI: https://doi.org/10.1007/s00540-011-1250-0

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Additive diuretic response of concurrent aminophylline and furosemide in children: a case series and a brief literature review

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