Skip to main content
Erschienen in: Clinical Journal of Gastroenterology 4/2021

08.06.2021 | Case Report

An advanced case of gastric histiocytic sarcoma treated with chemotherapy and gastrectomy: a case report and review of literature

verfasst von: Ryu Matsunaga, Yoshikazu Kanazawa, Kunihiko Matsuno, Daisuke Kakinuma, Taichiro Tokura, Atsushi Marumo, Shunsuke Yui, Fumihiko Ando, Yuka Masuda, Nobutoshi Hagiwara, Tsutomu Nomura, Shunji Kato, Toshiro Yoshiyuki, Yukako Domoto, Takashi Sakatani, Ryuji Ohashi, Koiti Inokuchi, Hiroshi Yoshida

Erschienen in: Clinical Journal of Gastroenterology | Ausgabe 4/2021

Einloggen, um Zugang zu erhalten

Abstract

Histiocytic sarcoma is a relatively new disease category and the gastrointestinal origin is sporadic. We report a case of a 74-year-old woman who underwent chemotherapy and proximal gastrectomy for extremely rare, advanced gastric histiocytic sarcoma. The resected specimen was subjected to numerous immunostainings to meet the diagnostic criteria of histiocytic sarcoma and was positive for the histiocyte markers’ cluster of differentiation 68 and lysozyme. The markers of Langerhans cells, follicular dendritic cells, and myelocyte were all negative. Six reports of surgical resection of histiocytic sarcoma originating in the stomach exist, including our case. We reviewed the clinical course and the histological and immunohistochemical diagnostic features of surgically resected gastric histiocytic sarcoma.
Literatur
1.
Zurück zum Zitat Weiss LM, Dura T, Grogan TM, et al. Histiocytic and dendritic cell neoplasms. In: Jaffe ES, Harris NL, Stein H, et al., editors. World Health Organization classification of tumors: pathology and genetics of tumours of haematopoietic and lymphoid tissues. France: IARC Press; 2001. p. 278–89. Weiss LM, Dura T, Grogan TM, et al. Histiocytic and dendritic cell neoplasms. In: Jaffe ES, Harris NL, Stein H, et al., editors. World Health Organization classification of tumors: pathology and genetics of tumours of haematopoietic and lymphoid tissues. France: IARC Press; 2001. p. 278–89.
2.
Zurück zum Zitat Grogan TM, Pileri SA, Chan JK, et al. Histiocytic sarcoma. In: Swerdlow SH, Campo E, Harris NL, et al., editors. World Health Organization classification of tumours of haematopoietic and lymphoid tissues. France: IARC Press; 2008. p. 356–7. Grogan TM, Pileri SA, Chan JK, et al. Histiocytic sarcoma. In: Swerdlow SH, Campo E, Harris NL, et al., editors. World Health Organization classification of tumours of haematopoietic and lymphoid tissues. France: IARC Press; 2008. p. 356–7.
3.
Zurück zum Zitat Kommalapati A, Tella SH, Durkin M, et al. Histiocytic sarcoma: a population-based analysis of incidence, demographic disparities, and long-term outcomes. Blood. 2018;131:265–8.CrossRef Kommalapati A, Tella SH, Durkin M, et al. Histiocytic sarcoma: a population-based analysis of incidence, demographic disparities, and long-term outcomes. Blood. 2018;131:265–8.CrossRef
4.
Zurück zum Zitat Congyang L, Xinggui W, Hao L, et al. Synchronous histiocytic sarcoma and diffuse large B cell lymphoma involving the stomach: a case report and review of the literature. Int J Hematol. 2011;93:247–52.CrossRef Congyang L, Xinggui W, Hao L, et al. Synchronous histiocytic sarcoma and diffuse large B cell lymphoma involving the stomach: a case report and review of the literature. Int J Hematol. 2011;93:247–52.CrossRef
5.
Zurück zum Zitat Sundersingh S, Majhi U, Seshadhri RA, et al. Multifocal histiocytic sarcoma of the gastrointestinal tract. Indian J Pathol Microbiol. 2012;55:233–5.CrossRef Sundersingh S, Majhi U, Seshadhri RA, et al. Multifocal histiocytic sarcoma of the gastrointestinal tract. Indian J Pathol Microbiol. 2012;55:233–5.CrossRef
6.
Zurück zum Zitat Shen XZ, Liu F, Ni RJ, Wang BY. Primary histiocytic sarcoma of the stomach: a case report with imaging findings. World J Gastroenterol. 2013;19:422–5.CrossRef Shen XZ, Liu F, Ni RJ, Wang BY. Primary histiocytic sarcoma of the stomach: a case report with imaging findings. World J Gastroenterol. 2013;19:422–5.CrossRef
7.
Zurück zum Zitat Hanaoka T, Jingu K, Tochigi T, et al. A case of G-CSF-producing histiocytic sarcoma of the stomach. Int Surg. 2015;100:568–73.CrossRef Hanaoka T, Jingu K, Tochigi T, et al. A case of G-CSF-producing histiocytic sarcoma of the stomach. Int Surg. 2015;100:568–73.CrossRef
8.
Zurück zum Zitat Petkova NY, Hristoskova RG, Guenova ML, et al. A rare case of primary histiocytic sarcoma of the stomach. Folia Med (Plovdiv). 2018;60:318–22.CrossRef Petkova NY, Hristoskova RG, Guenova ML, et al. A rare case of primary histiocytic sarcoma of the stomach. Folia Med (Plovdiv). 2018;60:318–22.CrossRef
9.
Zurück zum Zitat Pileri SA, Grogan TM, Harris NL, et al. Tumours of histiocytes and accessory dendritic cells: an immunohistochemical approach to classification from the International Lymphoma Study Group based on 61 cases. Histopathology. 2002;41:1–29.CrossRef Pileri SA, Grogan TM, Harris NL, et al. Tumours of histiocytes and accessory dendritic cells: an immunohistochemical approach to classification from the International Lymphoma Study Group based on 61 cases. Histopathology. 2002;41:1–29.CrossRef
10.
Zurück zum Zitat Hornick JL, Jaffe ES, Fletcher CD. Extranodal histiocytic sarcoma: clinicopathologic analysis of 14 cases of a rare epithelioid malignancy. Am J Surg Pathol. 2004;28:1133–44.CrossRef Hornick JL, Jaffe ES, Fletcher CD. Extranodal histiocytic sarcoma: clinicopathologic analysis of 14 cases of a rare epithelioid malignancy. Am J Surg Pathol. 2004;28:1133–44.CrossRef
11.
Zurück zum Zitat Copie-Bergman C, Wotherspoon AC, Norton AJ, et al. True histiocytic lymphoma: a morphologic, immunohistochemical, and molecular genetic study of 13 cases. Am J Surg Pathol. 1998;22:1386–92.CrossRef Copie-Bergman C, Wotherspoon AC, Norton AJ, et al. True histiocytic lymphoma: a morphologic, immunohistochemical, and molecular genetic study of 13 cases. Am J Surg Pathol. 1998;22:1386–92.CrossRef
12.
Zurück zum Zitat Vos JA, Abbondanzo SL, Barekman CL, et al. Histiocytic sarcoma: a study of five cases including the histiocyte marker CD163. Mod Pathol. 2005;18:693–704.CrossRef Vos JA, Abbondanzo SL, Barekman CL, et al. Histiocytic sarcoma: a study of five cases including the histiocyte marker CD163. Mod Pathol. 2005;18:693–704.CrossRef
13.
Zurück zum Zitat Almond LM, Charalampakis M, Ford SJ, et al. Myeloid sarcoma: presentation, diagnosis, and treatment. Clin Lymphoma Myeloma Leuk. 2017;17:263–7.CrossRef Almond LM, Charalampakis M, Ford SJ, et al. Myeloid sarcoma: presentation, diagnosis, and treatment. Clin Lymphoma Myeloma Leuk. 2017;17:263–7.CrossRef
14.
Zurück zum Zitat Döhner H, Estey E, Grimwade D, et al. Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel. Blood. 2017;129(4):424–47.CrossRef Döhner H, Estey E, Grimwade D, et al. Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel. Blood. 2017;129(4):424–47.CrossRef
15.
Zurück zum Zitat Shahin OA, Ravandi F. Myeloid sarcoma. Curr Opin Hematol. 2020;27:88–94.CrossRef Shahin OA, Ravandi F. Myeloid sarcoma. Curr Opin Hematol. 2020;27:88–94.CrossRef
16.
Zurück zum Zitat Takemori H, Sakata Y, Suzuki H, et al. A case of malignant histiocytosis successfully treated with combination interferon and etoposide therapy. Jpn J Clin Oncol. 1990;20:431–5.PubMed Takemori H, Sakata Y, Suzuki H, et al. A case of malignant histiocytosis successfully treated with combination interferon and etoposide therapy. Jpn J Clin Oncol. 1990;20:431–5.PubMed
17.
Zurück zum Zitat Tsujimura H, Miyaki T, Yamada S, et al. Successful treatment of histiocytic sarcoma with induction chemotherapy consisting of dose-escalated CHOP plus etoposide and upfront consolidation auto-transplantation. Int J Hematol. 2014;100:507–10.CrossRef Tsujimura H, Miyaki T, Yamada S, et al. Successful treatment of histiocytic sarcoma with induction chemotherapy consisting of dose-escalated CHOP plus etoposide and upfront consolidation auto-transplantation. Int J Hematol. 2014;100:507–10.CrossRef
18.
Zurück zum Zitat Narita K, Noro R, Seike M, et al. Successful treatment of histiocytic sarcoma and concurrent HIV infection using a combination of CHOP and antiretroviral therapy. Intern Med. 2013;52(24):2805–9.CrossRef Narita K, Noro R, Seike M, et al. Successful treatment of histiocytic sarcoma and concurrent HIV infection using a combination of CHOP and antiretroviral therapy. Intern Med. 2013;52(24):2805–9.CrossRef
19.
Zurück zum Zitat Chen X, Zhang L, Wang J, et al. Complete response after chemotherapy and radiotherapy of a tonsillar histiocytic sarcoma with regional lymph node involvement: a case report and review of the literature. Int J Clin Exp Med. 2015;8(9):16808–12.PubMedPubMedCentral Chen X, Zhang L, Wang J, et al. Complete response after chemotherapy and radiotherapy of a tonsillar histiocytic sarcoma with regional lymph node involvement: a case report and review of the literature. Int J Clin Exp Med. 2015;8(9):16808–12.PubMedPubMedCentral
20.
Zurück zum Zitat Zhao J, Niu X, Wang Z, et al. Histiocytic sarcoma combined with acute monocytic leukemia: a case report. Diagn Pathol. 2015;19(10):110.CrossRef Zhao J, Niu X, Wang Z, et al. Histiocytic sarcoma combined with acute monocytic leukemia: a case report. Diagn Pathol. 2015;19(10):110.CrossRef
21.
Zurück zum Zitat Voruz S, Cairoli A, Naveiras O, et al. Response to MEK inhibition with trametinib and tyrosine kinase inhibition with imatinib in multifocal histiocytic sarcoma. Haematologica. 2018;103:e39–41.CrossRef Voruz S, Cairoli A, Naveiras O, et al. Response to MEK inhibition with trametinib and tyrosine kinase inhibition with imatinib in multifocal histiocytic sarcoma. Haematologica. 2018;103:e39–41.CrossRef
22.
Zurück zum Zitat Takada M, Parys M, Gregory-Bryson E, et al. A novel canine histiocytic sarcoma cell line: initial characterization and utilization for drug screening studies. BMC Cancer. 2018;18:237.CrossRef Takada M, Parys M, Gregory-Bryson E, et al. A novel canine histiocytic sarcoma cell line: initial characterization and utilization for drug screening studies. BMC Cancer. 2018;18:237.CrossRef
Metadaten
Titel
An advanced case of gastric histiocytic sarcoma treated with chemotherapy and gastrectomy: a case report and review of literature
verfasst von
Ryu Matsunaga
Yoshikazu Kanazawa
Kunihiko Matsuno
Daisuke Kakinuma
Taichiro Tokura
Atsushi Marumo
Shunsuke Yui
Fumihiko Ando
Yuka Masuda
Nobutoshi Hagiwara
Tsutomu Nomura
Shunji Kato
Toshiro Yoshiyuki
Yukako Domoto
Takashi Sakatani
Ryuji Ohashi
Koiti Inokuchi
Hiroshi Yoshida
Publikationsdatum
08.06.2021
Verlag
Springer Singapore
Erschienen in
Clinical Journal of Gastroenterology / Ausgabe 4/2021
Print ISSN: 1865-7257
Elektronische ISSN: 1865-7265
DOI
https://doi.org/10.1007/s12328-021-01438-y

Weitere Artikel der Ausgabe 4/2021

Clinical Journal of Gastroenterology 4/2021 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

RAS-Blocker bei Hyperkaliämie möglichst nicht sofort absetzen

14.05.2024 Hyperkaliämie Nachrichten

Bei ausgeprägter Nierenfunktionsstörung steigen unter der Einnahme von Renin-Angiotensin-System(RAS)-Hemmstoffen nicht selten die Serumkaliumspiegel. Was in diesem Fall zu tun ist, erklärte Prof. Jürgen Floege beim diesjährigen Allgemeinmedizin-Update-Seminar.

Gestationsdiabetes: In der zweiten Schwangerschaft folgenreicher als in der ersten

13.05.2024 Gestationsdiabetes Nachrichten

Das Risiko, nach einem Gestationsdiabetes einen Typ-2-Diabetes zu entwickeln, hängt nicht nur von der Zahl, sondern auch von der Reihenfolge der betroffenen Schwangerschaften ab.

Labor, CT-Anthropometrie zeigen Risiko für Pankreaskrebs

13.05.2024 Pankreaskarzinom Nachrichten

Gerade bei aggressiven Malignomen wie dem duktalen Adenokarzinom des Pankreas könnte Früherkennung die Therapiechancen verbessern. Noch jedoch klafft hier eine Lücke. Ein Studienteam hat einen Weg gesucht, sie zu schließen.

Battle of Experts: Sport vs. Spritze bei Adipositas und Typ-2-Diabetes

11.05.2024 DDG-Jahrestagung 2024 Kongressbericht

Im Battle of Experts traten zwei Experten auf dem Diabeteskongress gegeneinander an: Die eine vertrat die Auffassung „Sport statt Spritze“ bei Adipositas und Typ-2-Diabetes, der andere forderte „Spritze statt Sport!“ Am Ende waren sie sich aber einig: Die Kombination aus beidem erzielt die besten Ergebnisse.

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.