nach oben

Erschienen in:

01.08.2011 | Original Article

Anemia in cats infected by Trypanosoma evansi

verfasst von: Aleksandro Schafer da Silva, Patrícia Wolkmer, Márcio Marcio Costa, Sonia Terezinha dos Anjos Lopes, Silvia Gonzalez Monteiro

Erschienen in: Comparative Clinical Pathology | Ausgabe 4/2011

Einloggen, um Zugang zu erhalten

Abstract

One of the main characteristics of the trypanosomosis is the development of anemia, although its pathogenesis still remains unclear. Therefore, the objective of this study was to discuss the possible pathogenesis of anemia in the infection by Trypanosoma evansi in cats. A study using an experimental model with T. evansi-infected cats reported changes in serum iron levels, alterations in the activity of enzymes of the cholinergic system, and oxidative stress correlated to normocytic, normochromic, and regenerative anemia. During this article, the aforementioned parameters will be simultaneously analyzed and related to hematological parameters that determine anemia in cats infected with this protozoan.

Assoku RKG (1975) Immunological studies of the mechanism of anaemia in experimental Trypanosoma evansi infection in rats. Int J Parasitol 5:137–145PubMedCrossRef

Audu PA, Esievo KA, Mohamed G, Ajanusi OJ (1999) Studies of infectivity and pathogenicity of an isolate of Trypanosoma evansi in Yankasa sheep. Vet Parasitol 86:185–190. doi:10.1016/S0304-4017(99)00141-7 PubMedCrossRef

Bush BM (2004) Interpretação de resultados laboratoriais para clínicos de pequenos animais. Roca, São Paulo

Choudhury A, Misra KK (1972) Experimental infection of T. evansi in the cat. Trans R Soc Trop Med Hyg 66(4):672–673PubMedCrossRef

Da Silva AS, Zanette RA, Wolkmer P, Costa MM, Oliveira CB, Soares CDM, Santurio JM, Lopes STA, Monteiro SG (2009a) Clinical aspects of cats experimentally infected with Trypanosoma evansi. Comp Clin Pathol. doi:10.1007/s00580-009-0903-y

Da Silva AS, Zanette RA, Wolkmer P, Costa MM, Gressler LT, Faccio L, Santurio JM, Lopes STA, Monteiro SG (2009b) Trypanosoma evansi: hematologic changes in experimentally infected cats. Exp Parasitol 123:31–34. doi:10.1016/j.exppara.2009.05.008 PubMedCrossRef

Da Silva AS, Hoehne L, Tonin AA, Zanette RA, Wolkmer P, Costa MM, Moraes DP, Flores ÉMM, Santurio JM, Lopes STA, Monteiro SG (2009c) Trypanosoma evansi: levels of copper, iron and zinc in the bloodstream of infected cats. Exp Parasitol 123:35–38. doi:10.1016/j.exppara.2009.05.007 PubMedCrossRef

Da Silva AS, Spanevello R, Stefanello N, Wolkmer P, Costa MM, Zanette RA, Lopes STA, Santurio JM, Schetinger MRC, Monteiro SG (2009d) Influence of Trypanosoma evansi in blood, plasma, and brain cholinesterase of experimentally infected cats. Res Vet Sci. doi:10.1016/j.rvsc.2009.08.011

Da Silva AS, Wolkmer P, Machado CM, Paim F, Oliveira CB, Zanette RA, Santurio JM, Lopes STA, Monteiro SG (2009e) Lipid peroxidation in cats experimentally infected with Trypanosoma evansi. Parasitol Res 106:157–161. doi:10.1007/s00436-009-1642-3 PubMedCrossRef

Dakshinkar NP, Dhoot VM, Uphadhye SV, Bhojne GR, Sarode DB, Kolte SW (2002) Trypanasomiasis in a jungle cat. Indian Vet J 79(1):66–67

Jatkar PR, Purohit MS (1971) Pathogenesis of anemia in Trypanosoma evansi infection. I. Haematology. Indian Vet J 48:239–244PubMed

Jenkins GC, Facer CA (1985) Hematology of African trypanosomiasis. In: Tizard I (ed) Immunology and pathogenesis of trypanosomiasis. CRC Press, Boca Raton, pp 13–44

Jha R, Rizvi SI (2009) Age-dependent decline in erythrocyte acetylcholinesterase activity: correlation with oxidative stress. Biomed Pap Med Fac PalackyÂ Univ Olomouc Czech Repub 153:195–198

Manohar BM, Selvaraj J, Jayathangaraj MG, Khan PN (2003) Pathology of Trypanosoma evansi infection in a tiger. Indian Vet J 80:505–507

Maudlin I, Holmes P, Miles MA (2004) The trypanosomiases. CABI Publishing, WallingfordCrossRef

Paikne DL, Dhake PR (1974) Trypanosomiasis in a domestic cat (Felis catus). Indian Vet J 51:387

Repetto MG, Ferrarotti NF, Boveris A (2009) The involvement of transition metal ions on iron-dependent lipid peroxidation. Arch Toxicol. doi:10.1007/s00204-009-0487-y PubMed

Saleh MA, Al-Salahy MB, Sanousi AS (2009) Oxidative stress in blood of camels (Camelus dromedaries) naturally infected with Trypanosoma evansi. Vet Parasitol 162:192–199. doi:10.1016/j.vetpar.2009.03.035 PubMedCrossRef

Scheidle G (1982) Das infektionsverhalten von Trypanosoma evansi (Stamm Manila) in vershiedenen tierarten. Dissertation, Ludwig-Maximillians Universitat Munchen.

Serobyan N, Jagannathan S, Orlovskaya I, Schraufstatter I, Skok M, Loring J, Khaldoyanidi S (2007) The cholinergic system is involved in regulation of the development of the hematopoietic system. Life Sci 80:2352–2360. doi:10.1016/j.lfs.2007.04.017 PubMedCrossRef

Shehu SA, Ibrahim NDG, Esievo KAN, Mohammed G (2006) Neuraminidase (Sialidase) activity and its role in development of anaemia in Trypanosoma evansi infection. J Appl Sci 6:2779–2783CrossRef

Sies H (1991) Oxidative stress: from basic research to clinical application. Am J Med 91:31–38CrossRef

Silva RAMS, Seidl A, Ramirez L, Dávila AMR (2002) Trypanosoma evansi e Trypanosoma vivax: Biologia, Diagnóstico e controle. Embrapa Pantanal, Corumbá

Soreq H, Patinkin D, Lev-Lehman E, Grifman M, Ginzberg D, Ecksteint F, Zakut H (1994) Antisense oligonucleotide inhibition of acetyicholinesterase gene expression induces progenitor cell expansion and suppresses hematopoietic apoptosis ex vivo. Proc Natl Acad Sci 91:7907–7911PubMedCrossRef

Tarello W (2005) Trypanosoma evansi infection in three cats. Rev Med Vet 156:133–134

Thirunavukkarasu PS, George RRS, Nambi AP, Ramesh S, Vasu K (2000) Trypanosomiosis in a cat—a clinical report. Indian Vet J 77:428–429

Wolkmer P, Da Silva AS, Carnelutti JF, Paim FC, Traesel C, Lopes STA, Monteiro SG (2009) Lipid peroxidation associated with anemia in rats experimentally infected with Trypanosoma evansi. Vet Parasitol 165:41–46. doi:10.1016/j.vetpar.2009.06.032 PubMedCrossRef

Titel: Anemia in cats infected by Trypanosoma evansi
verfasst von: Aleksandro Schafer da Silva
Patrícia Wolkmer
Márcio Marcio Costa
Sonia Terezinha dos Anjos Lopes
Silvia Gonzalez Monteiro
Publikationsdatum: 01.08.2011
Verlag: Springer-Verlag
Erschienen in: Comparative Clinical Pathology / Ausgabe 4/2011
Print ISSN: 1618-5641
Elektronische ISSN: 1618-565X
DOI: https://doi.org/10.1007/s00580-010-1009-2

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Anemia in cats infected by Trypanosoma evansi

Abstract

Neu im Fachgebiet Pathologie

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 4/2011

Comparative study on the determination of serum thyroid hormones by two methods of immunoassay in broiler breeder poultry

Use of prolactin as an indicator of stress in Marwari sheep from arid tracts in India

Study of the hemogram and platelet function in blood donor dogs

Antioxidant and bone healing effect of vitamin E in an experimental osteotomy model in dogs

Clinicopathologic findings in goats exposed to drinking water experimentally contaminated with varied low percentages of NPK 15–15–15 fertilizer

Clinical relevance of angiopoietin-1, angiopoietin-2, and their receptor Tie-2 expression in acute myeloid leukemia

Neu im Fachgebiet Pathologie

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie