Antibiotic resistance profile of Trueperella pyogenes isolated from three cases of goat kids affected by sever cardiopulmonary disease

Three 20-day-old female Cashmere (Raini) goat kids were presented in a sternal recumbency status with 3 weeks history of bilateral mucopurulent nasal discharge, anorexia, lethargy, and jugular distention hemato-biochemical profile showed leukocytosis (monocytosis, neutrophilia with bandemia) and a significant increase (p < 0.05) in the serum concentrations of total protein and fibrinogen. The goats died 1 week after treatment because of the severity of the disease. At necropsy, multiple pyogenic abscesses in the liver, myocardial abscesses, and fibrous pleural adhesions were observed. Histopathological examination revealed supportive hepatitis, formation of granulation tissue in the epicardial and myocardial layer of the heart and chronic suppurative bronchopneumonia with granulation tissue in the pleura. In bacteriological examination, Trueperella pyogenes (T. pyogenes) was isolated from the abscess and confirmed by PCR. The isolated bacteria showed the most susceptibility to the cefotaxime and the less susceptibility to oxytetracycline and gentamycin. Overall, this is the first report, which offered this bacterium as a causative agent of the wide ranges of pathological conditions in Cashmere goats. Suitable antimicrobial therapy of which the Clinician should be aware.